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Functional studies of host-specific ephrin-B ligands as Henipavirus receptors
Virology, 2008 Hendra virus (HeV) and Nipah virus (NiV) are closely related paramyxoviruses that infect and cause disease in a wide range of mammalian hosts. To determine whether host receptor molecules play a role in species-specific and/or virus-specific infection we
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Ferret Models for Henipavirus Infection
2023Henipaviruses are emerging zoonotic viruses that can cause outbreaks of severe respiratory and neurological disease in humans and animals such as horses. The mechanism by which these viruses can cause disease remain largely unknown and to date there are no therapeutics or vaccines approved for use in humans.
Rockx, Barry, Mire, Chad E.
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Henipavirus Infections - An Expanding Zoonosis from Fruit Bats
Journal of Disaster Research, 2011 The henipavirus genus has two members – the Hendra virus (HeV) and the Nipah virus (NiV). HeV and NiV, identified in the 1990s as a paramyxovirus, cause fatalities in humans and animals. They are now classified as biosafety level 4 pathogens. HeV caused fatal respiratory infection in horses and humans in Australia in 1994, in which 2 persons died.
Chieko Kai, Misako Yoneda
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Profiling Host MicroRNA Responses to Henipavirus Infection
2023Diseases caused by henipaviruses feature incubation periods of up to 16 days, during which infected animals may show no apparent signs of disease yet be capable of transmitting the virus to humans. This risk has prompted research into host-derived biomarkers for early disease detection. Here, we describe a methodology for the assaying of host microRNAs
Ryan J, Farr +5 more
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Animal models of henipavirus infection: A review
The Veterinary Journal, 2009Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level four pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy.
Hana M, Weingartl +2 more
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Overview of Experimental Vaccines and Antiviral Therapeutics for Henipavirus Infection
2023Hendra virus (HeV) and Nipah virus (NiV) are highly pathogenic paramyxoviruses, which have emerged in recent decades and cause sporadic outbreaks of respiratory and encephalitic disease in Australia and Southeast Asia, respectively. Over two billion people currently live in regions potentially at risk due to the wide range of the Pteropus fruit bat ...
Benjamin A, Satterfield +2 more
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Low leukocyte count in Langya henipavirus and severity of infection
The Egyptian Journal of Haematology, 2022Aim The aim is to determine the leukocyte count in Langya henipavirus infection. Background The ‘Langya henipavirus’ is a brand new viral pathogen that first appeared in 2022. In the Chinese cities where this new virus was discovered, a big population was found with this infection ...
Rujittika Mungmunpuntipantip +1 more
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Host Transcriptome Analysis of Ferret Tissues Following Henipavirus Infection
2023Ferrets are commonly used as experimental models of infection for a variety of viruses due to their susceptibility to human respiratory viruses and the close resemblance of pathological outcomes found in human infections. Even though ferret-specific reagents are limited, the use of ferrets as a preclinical experimental model of infection has gained ...
Tian S, Zeng +3 more
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Infection and transmission of henipavirus in animals
Comparative Immunology, Microbiology and Infectious DiseasesHenipavirus (HNV) is well known for two zoonotic viruses in the genus, Hendra virus (HeV) and Nipah virus (NiV), which pose serious threat to human and animal health. In August 2022, a third zoonotic virus in the genus Henipavirus, Langya virus (LayV), was discovered in China.
Xinyu Qiu, Feng Wang, Ailong Sha
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2023
The olfactory receptor neurons (ORNs) are a unique cell type involved in the initial perception of odors. These specialized epithelial cells are located in the neuroepithelium of the nasal cavities and directly connect the nasal cavity with the central nervous system (CNS) via axons, which traverse the cribriform plate to synapse within the olfactory ...
Ozdener, Mehmet Hakan +2 more
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The olfactory receptor neurons (ORNs) are a unique cell type involved in the initial perception of odors. These specialized epithelial cells are located in the neuroepithelium of the nasal cavities and directly connect the nasal cavity with the central nervous system (CNS) via axons, which traverse the cribriform plate to synapse within the olfactory ...
Ozdener, Mehmet Hakan +2 more
openaire +2 more sources