Results 101 to 110 of about 1,925 (167)

Discovery and Optimization of First-in-Class Furopyrimidine-based Inhibitors of Henipaviruses

Journal of Medicinal Chemistry
Henipaviruses such as Nipah (NiV) and Hendra (HeV) are zoonotic pathogens that cause severe and often fatal respiratory illness and encephalitis in both animals and humans. These viruses exhibit high transmissibility and pandemic potential, a situation made worse by the absence of appropriate pharmaceutical countermeasures.
Irina N. Gaisina, Malaika D. Argade, Ryan Bott, Sean P. Bradley, Łukasz Tomorowicz, Mario Alvarez, Jazmin M. Galván Achi, Robert W. Cross, Viktoriya Borisevich, Rachel O’Toole, Moushimi Amaya, Christian A. Zielinski, Arsen M. Gaisin, Dejan Nikolic, Paul R. Carlier, Manu Anantpadma, Terry W. Moore, Christopher C. Broder, Thomas W. Geisbert, Norton P. Peet, Lijun Rong   +20 more
openaire   +2 more sources

Qualitative Release Assessment to Estimate the Likelihood of Henipavirus Entering the United Kingdom. PLoS One 2012

, 2020
The genus Henipavirus includes Hendra virus (HeV) and Nipah virus (NiV), for which fruit bats (particularly those of the genus Pteropus) are considered to be the wildlife reservoir. The recognition of henipaviruses occurring across a wider geographic and
Emma L Snary, Anthony R Fooks, Vick Ramnial, Andrew C Breed, Ben Stephenson, Hume E Field   +5 more
core  

Not Available

, 2018
Not AvailableHendra virus (HeV) and Nipah virus (NiV) are among a group of emerging bat-borne paramyxoviruses that have crossed their species-barrier several times by infecting several hosts with a high fatality rate in human beings.
Peteriya, A. K., Sood, R., Kumar, N., Kaushik, R., Bhatia, S., Lee, B., Bhat, S., Kulkarni, D. D., Singh, V. P.   +8 more
core  

Henipaviruses at the threshold: preparedness in the era of recurrent spillover. [PDF]

Emerg Microbes Infect
Wang X, Zhang W.
europepmc   +1 more source

Comprehensive mapping of human CD4⁺ T cell epitopes for Nipah and measles as prototype Paramyxoviruses. [PDF]

Cell Rep Med
Tarke A, Macias M, Morales CF, Michaelis T, Siddiqui L, Yu ED, Trevizani R, Zuniga A, Zmasek C, Phillips E, Mallal S, Lin B, Estevez JO, Erlich JR, Johnson NV, McLellan JS, Frazier A, da Silva Antunes R, Tan GS, Grifoni A, Sette A.   +20 more
europepmc   +1 more source

Integrating Prevention and Response at the Crossroads of Henipavirus Preparedness, Hendra@30 Conference, 2024. [PDF]

Emerg Infect Dis
Halpin K, Román RG, de Wit E, Peel AJ, Epstein JH, Barr J, Edwards SJ, Tripp MN, Blanch-Lázaro B, Linnegar B, Habarugira G, Marsh GA, Anderson D, Chang LY, Markotter W.   +14 more
europepmc   +1 more source

Novel Henipavirus, Salt Gully Virus, Isolated from Pteropid Bats, Australia. [PDF]

Emerg Infect Dis
Barr J, Caruso S, Edwards SJ, Todd S, Smith I, Tachedjian M, Crameri G, Wang LF, Marsh GA.   +8 more
europepmc   +1 more source

Analysis of Recombinant Cedar Virus Infection and Cross-Protection Against Related Henipaviruses in African Green Monkeys. [PDF]

Viruses
Pigeaud DD, Amaya M, Borisevich V, Fenton KA, Agans KN, Woolsey C, Dimitrov AS, Prasad AN, Dobias NS, Deer DJ, Geisbert JB, Cross RW, Broder CC, Geisbert TW.   +13 more
europepmc   +1 more source

Three decades of discovery: An overview of Hendra virus, the original Henipavirus. [PDF]

PLoS Negl Trop Dis
Halpin K, Gómez Román R.
europepmc   +1 more source

Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access. [PDF]

Sci Adv
Jayachandran RB, Quignon E, Renner M.
europepmc   +1 more source