Results 81 to 90 of about 2,019 (169)

Current progress towards prevention of Nipah and Hendra disease in humans: A scoping review of vaccine and monoclonal antibody candidates being evaluated in clinical trials

Tropical Medicine &International Health, Volume 29, Issue 5, Page 354-364, May 2024.
Abstract Objectives Nipah and Hendra are deadly zoonotic diseases with pandemic potential. To date, no human vaccine or monoclonal antibody (mAb) has been licensed to prevent disease caused by these pathogens. The aim of this scoping review was to identify and describe all Phase I, II, and III clinical trials of vaccine candidates or mAbs candidates ...
Valerie Rodrigue, Katie Gravagna, Jacqueline Yao, Vaidehi Nafade, Nicole E. Basta   +4 more
wiley   +1 more source

Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections

Frontiers in Microbiology, 2020
Hendra virus (HeV) and Cedar virus (CedV) are henipaviruses, which fall into the Paramyxoviridae family of single-stranded, negative-sense RNA viruses. HeV is classified as a Biosafety Level-4 (BSL-4) agent, as it is highly pathogenic and is often fatal ...
Mingyue Chen, Mingyue Chen, Mingyue Chen, Mary Tachedjian, Glenn A. Marsh, Jie Cui, Jie Cui, Lin-Fa Wang, Lin-Fa Wang   +8 more
doaj   +1 more source

Pathology and host-pathogen interactions in a golden Syrian hamster model of Nipah virus infection

Frontiers in Veterinary Science
Nipah virus (NiV) is recognized as one of the key pathogens with pandemic potential. We have recently established a NiV hamster model, which reproduces a highly similar disease to that observed in human cases, including respiratory and neurological signs
Inés Ruedas-Torres, Stephen Findlay-Wilson, Emma Kennedy, Stuart Dowall, Francisco Javier Salguero   +4 more
doaj   +1 more source

Experimental challenge of African green monkeys with contemporary Hendra virus isolates produces divergent clinical disease

Emerging Microbes and Infections
Hendra virus (HeV) is a medically important, zoonotic paramyxovirus that emerged over thirty years ago which causes severe, often fatal disease in humans and animals.
Declan D. Pigeaud, Karla A. Fenton, Jacquelyn Turcinovic, Viktoriya Borisevich, Krystle N. Agans, Daniel J. Deer, Mack B. Harrison, Alyssa C. Fears, Natalie S. Dobias, Ahbishek N. Prasad, Ina L. Smith, David T. Williams, Courtney B. Woolsey, Christopher C. Broder, Robert W. Cross, Thomas W. Geisbert   +15 more
doaj   +1 more source

Release pathways for henipaviruses to be released into the UK via (a) imported bats (all species), pigs, horses and companion animals; (b) “natural importation” of insectivorous bats; (c) via human travel; (d) via a tonne of imported foodstuffs.

, 2012
Release pathways for henipaviruses to be released into the UK via (a) imported bats (all species), pigs, horses and companion animals; (b) “natural importation” of insectivorous bats; (c) via human travel; (d) via a tonne of imported foodstuffs.
Anthony R. Fooks (44966), Andrew C. Breed (185310), Vick Ramnial (185307), Emma L. Snary (185304), Hume E. Field (145859), Ben Stephenson (185313)   +5 more
core   +1 more source

The C proteins of other known henipaviruses also enhance the budding of their cognate matrix proteins.

, 2016
(A) Phylogeny (based on the relatively conserved nucleocapsid protein, neighbor-joining tree from Clustal Omega, visualized in FigTree) for the henipaviruses as well as the “henipa-like” Mojiang virus (MojPV) and representative paramyxoviruses from each ...
Tatyana Yun (404063), Frederic Vigant (404060), Benhur Lee (78126), Sohui T. Won (553572), Brian E. Dawes (2796574), Wojciech Bartkowski (553573), Alexander N. Freiberg (95391), Arnold Park (237682), Olivier Pernet (2796571)   +8 more
core   +1 more source

Emerging henipaviruses and flying foxes – Conservation and management perspectives

Biological Conservation, 2006
Wildlife populations are affected by a series of emerging diseases, some of which pose a significant threat to their conservation. They can also be reservoirs of pathogens that threaten domestic animal and human health. In this paper, we review the ecology of two viruses that have caused significant disease in domestic animals and humans and are ...
Breed, Andrew C., Field, Hume E., Epstein, Jonathan H., Daszak, Peter   +3 more
openaire   +7 more sources

Antibodies to henipavirus or henipa-like viruses in domestic pigs in Ghana, West Africa.

PLoS ONE, 2011
Henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), have Pteropid bats as their known natural reservoirs. Antibodies against henipaviruses have been found in Eidolon helvum, an old world fruit bat species, and henipavirus-like nucleic acid has been ...
David T S Hayman, Lin-Fa Wang, Jennifer Barr, Kate S Baker, Richard Suu-Ire, Christopher C Broder, Andrew A Cunningham, James L N Wood   +7 more
doaj   +1 more source

Henipavirus Infections: Lessons from Animal Models

Pathogens, 2013
The Henipavirus genus contains two highly lethal viruses, the Hendra and Nipah viruses and one, recently discovered, apparently nonpathogenic member; Cedar virus.
Kévin P. Dhondt, Branka Horvat
doaj   +1 more source

Investigating the neuropathogenesis of henipaviruses in a newly established mouse model of encephalitis.

, 2015
© 2015 Dr. Johanna Nina Beatrix DupsHendra and Nipah are henipaviruses that cause severe and often fatal disease in humans. Human infection is characterised by an initial influenza like illness that can, and often does, progress to encephalitis.
Dups, Johanna Nina Beatrix
core   +1 more source