Results 71 to 80 of about 2,019 (169)
Immune evasion and pathogenesis of henipaviruses
Current Opinion in VirologyZoonotic viruses pose an escalating threat to global health, driven by climate change, deforestation, urbanization, and increased human-wildlife interactions. Among these threats, Henipaviruses - particularly Hendra virus and Nipah virus - have emerged as priority pathogens due to their severe clinical manifestations, broad host range, and pandemic ...
Juwan Kim +3 more
openaire +2 more sources
, 2023 The henipaviruses, Nipah virus (NiV), and Hendra virus (HeV) can cause fatal diseases in humans and animals, whereas Cedar virus is a nonpathogenic henipavirus.
Regina Z. Cer +12 more
core +1 more source
The FEBS Journal, Volume 292, Issue 3, Page 556-581, February 2025.The W proteins of Nipah and Hendra viruses exhibit fibrillation abilities in vitro, which have been attributed to the intrinsically disordered N‐terminal domain (NTD). Our research shows that the C‐terminal domain (CTD) of both viruses is intrinsically disordered and non‐fibrillogenic.
Giulia Pesce +5 more
wiley +1 more source
Tetracistronic minigenomes elucidate a functional promoter for Ghana virus and unveils Cedar virus replicase promiscuity for all henipaviruses [PDF]
Batborne henipaviruses, such as Nipah and Hendra viruses, represent a major threat to global health due to their propensity for spillover, severe pathogenicity, and high mortality rate in human hosts.
Klain, William R. +9 more
core +1 more source
Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein
Nature Communications, 2023 Henipaviruses such as Nipah virus (NiV) cause severe encephalitis with high fatality rates in humans. NiV fusion (F) glycoprotein is a key target of the host immune response. Here, Byrne et al.
Patrick O. Byrne +7 more
doaj +1 more source
Health Science Reports, Volume 7, Issue 12, December 2024.ABSTRACT Background and Aims The World Health Organization (WHO) recognized the potential for a severe international epidemic and introduced the term “Disease X” to classify pathogens that not yet identified. The Nipah virus (NiV) is highly dangerous due to its zoonotic nature, high mortality rate, and ability to cause severe clinical symptoms in ...
Samiha Mehnaz +4 more
wiley +1 more source
, 2020 Bats are unique among mammals due to the ability of powered flight and exceptional longevity. They are also asymptomatic hosts for numerous viruses, including recently emerged zoonotic Henipaviruses Nipah and Hendra, which are highly pathogenic for ...
Aurine, Noémie +8 more
core +1 more source
, 2016 A) Matrix proteins from henipaviruses inhibit IKKε-mediated IFNβ induction. HEK293T cells were transfected with IFNβ luciferase reporter and a Renilla control plasmid, in the presence or absence of NiV-M, HeV-M, GhV-M or CedV-M and IKKε, followed by ...
Preeti Bharaj (30274) +9 more
core +1 more source
The Unique Immune System of Bats: An Evolutionary Analysis and Bibliometric Study
Ecology and Evolution, Volume 14, Issue 11, November 2024.Through the evolutionary and bibliometric analyses, this study identified several critical immune genes and signaling pathways related to bat immunity. Currently, research on the immune system of bats primarily focuses on the themes of “efficient antiviral responses” and “inflammation suppression.” ABSTRACT Bats exhibit a greater capacity to tolerate ...
Rui Li +4 more
wiley +1 more source
Cedar virus: a novel Henipavirus isolated from Australian bats.
PLoS Pathogens, 2012 The genus Henipavirus in the family Paramyxoviridae contains two viruses, Hendra virus (HeV) and Nipah virus (NiV) for which pteropid bats act as the main natural reservoir.
Glenn A Marsh +15 more
doaj +1 more source