The application of genomics to emerging zoonotic viral diseases [PDF]
Interspecies transmission of pathogens may result in the emergence of new infectious diseases in humans as well as in domestic and wild animals. Genomics tools such as high-throughput sequencing, mRNA expression profiling, and microarray-based analysis ...
Andeweg, A.C. (Arno) +2 more
core +1 more source
Discovery and Genetic Characterization of Novel Paramyxoviruses Related to the Genus Henipavirus in Crocidura Species in the Republic of Korea [PDF]
Paramyxoviruses, negative-sense single-stranded RNA viruses, pose a critical threat to human public health. Currently, 78 species, 17 genera, and 4 subfamilies of paramyxoviruses are harbored by multiple natural reservoirs, including rodents, bats ...
Budhathoki, Shailesh +16 more
core +1 more source
Characteristics and Risk Perceptions of Ghanaians Potentially Exposed to Bat-Borne Zoonoses through Bushmeat. [PDF]
Emerging zoonotic pathogens from wildlife pose increasing public health threats globally. Bats, in particular, host an array of zoonotic pathogens, yet there is little research on how bats and humans interact, how people perceive bats and their ...
Cunningham, Andrew A +5 more
core +8 more sources
Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology
Bats are recognized to have distinct immune systems from other vertebrates that may allow them to host virulent pathogens without showing disease. However, these flying mammals are also incredibly diverse, such that bats should not be expected to be immunologically homogenous.
Daniel J. Becker +11 more
wiley +1 more source
Indirect ELISA based on Hendra and Nipah virus proteins for the detection of henipavirus specific antibodies in pigs. [PDF]
Hendra virus (HeV) and Nipah virus (NiV) belong to the genus Henipavirus in the family Paramyxoviridae. Henipavirus infections were first reported in the 1990's causing severe and often fatal outbreaks in domestic animals and humans in Southeast Asia and
Kerstin Fischer +8 more
doaj +1 more source
From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis
Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley +1 more source
Land Use Change and Infectious Disease Emergence
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli +6 more
wiley +1 more source
Abstract Hendra virus (HeV) is a biosafety level 4 human pathogen belonging to the Henipavirus genus within the Paramyxoviridae family. In HeV, the phosphoprotein‐encoding gene also drives the synthesis of the V and W proteins that are two major players in the host innate immune response evasion.
Frank Gondelaud +8 more
wiley +1 more source
Genetic diversity, infection prevalence, and possible transmission routes of Bartonella spp. in vampire bats [PDF]
Bartonella spp. are globally distributed bacteria that cause endocarditis in humans and domestic animals. Recent work has suggested bats as zoonotic reservoirs of some human Bartonella infections; however, the ecological and spatiotemporal patterns of ...
Altizer, Sonia +5 more
core +3 more sources
Ebolavirus evolution and emergence are associated with land use change
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Christian E. Lange +8 more
wiley +1 more source

