Results 21 to 30 of about 2,606 (185)

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

Advanced Science
Hendra and Nipah viruses (HNVs), zoonotic paramyxoviruses with >50% case fatality rates, cause fatal encephalitis and respiratory disease, yet lack approved therapies.
Yi Ren, Pengfei Fan, Xinghai Zhang, Ting Fang, Zhengshan Chen, Yanfeng Yao, Xiangyang Chi, Guanying Zhang, Xiaofan Zhao, Bingjie Sun, Fangxu Li, Zixuan Liu, Zhenwei Song, Baoyue Zhang, Cheng Peng, Entao Li, Yilong Yang, Jianmin Li, Sandra Chiu, Changming Yu   +19 more
doaj   +2 more sources

Structural Studies of Henipavirus Glycoproteins [PDF]

Viruses
Henipaviruses are a genus of emerging pathogens that includes the highly virulent Nipah and Hendra viruses that cause reoccurring outbreaks of disease.
Aaron J. May, Priyamvada Acharya
doaj   +2 more sources

Infectome analysis of bat kidneys from Yunnan province, China, reveals novel henipaviruses related to Hendra and Nipah viruses and prevalent bacterial and eukaryotic microbes. [PDF]

PLoS Pathogens
Bats are natural reservoirs for a wide range of microorganisms, including many notable zoonotic pathogens. However, the composition of the infectome (i.e., the collection of viral, bacterial and eukaryotic microorganisms) within bat kidneys remains ...
Guopeng Kuang, Tian Yang, Weihong Yang, Jing Wang, Hong Pan, Yuanfei Pan, Qin-Yu Gou, Wei-Chen Wu, Juan Wang, Lifeng Yang, Xi Han, Yao-Qing Chen, John-Sebastian Eden, Edward C Holmes, Mang Shi, Yun Feng   +15 more
doaj   +2 more sources

Henipavirus in Northern Short-Tailed Shrew, Alabama, USA [PDF]

Emerging Infectious Diseases
RNA metagenomic analysis of tissues from 4 wild-caught northern short-tailed shrews in Alabama, USA, revealed a novel henipavirus (family Paramyxoviridae).
Rhys H. Parry, KayLene Y.H. Yamada, Wendy R. Hood, Yang Zhao, Jinlong Y. Lu, Andrei Seluanov, Vera Gorbunova, Naphak Modhiran, Daniel Watterson, Ariel Isaacs   +9 more
doaj   +2 more sources

Serological and molecular analysis of henipavirus infections in synanthropic fruit bat and rodent populations in the Centre and North regions of Cameroon (2018–2020) [PDF]

BMC Veterinary Research
Background Bats and rodents have been identified as reservoirs for several highly pathogenic and zoonotic viruses including henipaviruses, a genus within the Paramyxoviridae family.
Cyrille Mbanwi Mbu’u, Pierre Gontao, Abel Wade, Maren Penning, Balal Sadeghi, Aristid Ekollo Mbange, Matthew LeBreton, Sylvain Leroy Sado Kamdem, Franziska Stoek, Martin Hermann Groschup, Wilfred Fon Mbacham, Anne Balkema-Buschmann   +11 more
doaj   +2 more sources

Prophylactic protection from lethal henipavirus disease mediated by Nipah-derived defective interfering particles is influenced by challenge virus strain and viral speciesResearch in context [PDF]

EBioMedicine
Summary: Background: Henipaviruses, including Nipah and Hendra viruses, are zoonotic pathogens that can cause severe respiratory and neurological diseases with high mortality rates in humans.
Stephen R. Welch, Jessica R. Spengler, Jessica R. Harmon, JoAnn D. Coleman-McCray, Sarah C. Genzer, Katherine A. Davies, Teresa E. Sorvillo, Florine E.M. Scholte, Sergio E. Rodriguez, Joel M. Montgomery, Stuart T. Nichol, Christina F. Spiropoulou   +11 more
doaj   +2 more sources

Paramyxoviruses in Old World fruit bats (Pteropodidae): An open database and synthesis of sampling effort, viral positivity, and coevolution. [PDF]

PLoS Negl Trop Dis
Over the past 30 years, research interest in the links between Old World fruit bats (family Pteropodidae) and paramyxoviruses has driven a rapid proliferation of surveillance studies in this system.
Juman MM, Restif O, Becker DJ.
europepmc   +3 more sources

Humans are urged to be vigilant against spillback infection of new henipaviruses

Frontiers in Immunology, 2022
Jin Zhang
exaly   +3 more sources

Idiosyncratic Mòjiāng virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses

Nature Communications, 2017
The attachment glycoprotein (HNV-G) of henipaviruses interacts with host receptors at the cell surface and is a major determinant of species tropism. Here the authors provide structural and functional evidence that the emergent henipavirus, Mòjiang virus,
Ilona A Rissanen, Patrick Hong, Sham Nambulli   +2 more
exaly   +2 more sources

Bat trait, genetic and pathogen data from large-scale investigations of African fruit bats, Eidolon helvum. [PDF]

, 2016
Bats, including African straw-coloured fruit bats (Eidolon helvum), have been highlighted as reservoirs of many recently emerged zoonotic viruses. This common, widespread and ecologically important species was the focus of longitudinal and continent-wide
Baker, Kate S, Breed, Andrew C, Cunningham, Andrew A, Fernández-Loras, Andrés, Fooks, Anthony R, Gembu, Guy-Crispin, Hayman, David TS, Lembo, Tiziana, Peel, Alison J, Sargan, David R, Suu-Ire, Richard, Wood, James LN   +11 more
core   +14 more sources