Results 31 to 40 of about 1,925 (167)

Idiosyncratic Mòjiāng virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses

Nature Communications, 2017
The attachment glycoprotein (HNV-G) of henipaviruses interacts with host receptors at the cell surface and is a major determinant of species tropism. Here the authors provide structural and functional evidence that the emergent henipavirus, Mòjiang virus,
Ilona Rissanen, Asim A. Ahmed, Kristopher Azarm, Shannon Beaty, Patrick Hong, Sham Nambulli, W. Paul Duprex, Benhur Lee, Thomas A. Bowden   +8 more
doaj   +2 more sources

Serological and molecular analysis of henipavirus infections in synanthropic fruit bat and rodent populations in the Centre and North regions of Cameroon (2018–2020) [PDF]

BMC Veterinary Research
Background Bats and rodents have been identified as reservoirs for several highly pathogenic and zoonotic viruses including henipaviruses, a genus within the Paramyxoviridae family.
Cyrille Mbanwi Mbu’u, Pierre Gontao, Abel Wade, Maren Penning, Balal Sadeghi, Aristid Ekollo Mbange, Matthew LeBreton, Sylvain Leroy Sado Kamdem, Franziska Stoek, Martin Hermann Groschup, Wilfred Fon Mbacham, Anne Balkema-Buschmann   +11 more
doaj   +2 more sources

Prophylactic protection from lethal henipavirus disease mediated by Nipah-derived defective interfering particles is influenced by challenge virus strain and viral speciesResearch in context [PDF]

EBioMedicine
Summary: Background: Henipaviruses, including Nipah and Hendra viruses, are zoonotic pathogens that can cause severe respiratory and neurological diseases with high mortality rates in humans.
Stephen R. Welch, Jessica R. Spengler, Jessica R. Harmon, JoAnn D. Coleman-McCray, Sarah C. Genzer, Katherine A. Davies, Teresa E. Sorvillo, Florine E.M. Scholte, Sergio E. Rodriguez, Joel M. Montgomery, Stuart T. Nichol, Christina F. Spiropoulou   +11 more
doaj   +2 more sources

Beyond the Headlines: Why Henipaviruses Warrant Our Attention

Acta Medica (Hradec Kralove, Czech Republic)
Henipaviruses, including Hendra and Nipah viruses, represent significant zoonotic threats with higher mortality rates. Due to limited therapeutic interventions, poses substantial challenges. These bat-borne pathogens were first identified in Australia (Hendra, 1994) and Malaysia (Nipah, 1998–1999), with subsequent multiple outbreaks.
Biplab Adhikari
openaire   +4 more sources

Evolution of Nipah Virus Infection: Past, Present, and Future Considerations

Tropical Medicine and Infectious Disease, 2021
Nipah virus (NiV) is a zoonotic paramyxovirus of the Henipavirus genus first identified in Malaysia in 1998. Henipaviruses have bat reservoir hosts and have been isolated from fruit bats found across Oceania, Asia, and Africa.
Naomi Hauser, Alexis C. Gushiken, Shivakumar Narayanan, Shyam Kottilil, Joel V. Chua   +4 more
doaj   +1 more source

Study on mecanisms of high pathogenicity of Henipaviruses

, 2014
Les Henipavirus sont des paramyxovirus zoonotiques émergents hautement pathogènes. Ils sont capables d’infecter un large spectre d’hôtes incluant notamment la chauve-souris frugivore (réservoir naturel), le porc et l’homme. Etant donné leur très grande dangerosité et en l’absence de traitements curatifs ou prophylactiques efficaces, ces virus doivent ...
Dhondt, Kévin
openaire   +2 more sources

The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import

Cells, 2020
Nipah and Hendra viruses are highly pathogenic, zoonotic henipaviruses that encode proteins that inhibit the host’s innate immune response. The W protein is one of four products encoded from the P gene and binds a number of host proteins to regulate ...
Sofiya Tsimbalyuk, Emily M. Cross, Mikayla Hoad, Camilla M. Donnelly, Justin A. Roby, Jade K. Forwood   +5 more
doaj   +1 more source

Reprogrammed Pteropus Bat Stem Cells as A Model to Study Host-Pathogen Interaction during Henipavirus Infection

Microorganisms, 2021
Bats are natural hosts for numerous zoonotic viruses, including henipaviruses, which are highly pathogenic for humans, livestock, and other mammals but do not induce clinical disease in bats.
Noémie Aurine, Camille Baquerre, Maria Gaudino, Christian Jean, Claire Dumont, Sylvie Rival-Gervier, Clémence Kress, Branka Horvat, Bertrand Pain   +8 more
doaj   +1 more source

Henipaviruses

, 2008
B.T. Eaton, L.-F. Wang
openaire   +2 more sources

A Survey of Henipavirus Tropism—Our Current Understanding from a Species/Organ and Cellular Level

Viruses, 2023
Henipaviruses are single-stranded RNA viruses that have been shown to be virulent in several species, including humans, pigs, horses, and rodents. Isolated nearly 30 years ago, these viruses have been shown to be of particular concern to public health ...
Sandra Diederich, Shawn Babiuk, Hani Boshra   +2 more
doaj   +1 more source