Results 91 to 100 of about 29,438 (248)

Exploring dietary adaptations in Ursus minimus: a 3D geometric morphometric analysis of the mandible

open access: yesBoreas, EarlyView.
Using 3D geometric morphometrics, the dietary adaptations of the extinct Auvergne bear (Ursus minimus) are analysed. Its mandibular morphology aligns more closely with omnivorous rather than insectivorous bears, challenging current ideas. The extinct bear Ursus minimus, which lived in Europe during the Pliocene and possibly Early Pleistocene, is ...
Anneke H. van Heteren
wiley   +1 more source

Synthesis of new cytotoxic aminoanthraquinone derivatives via nucleophilic substitution reactions [PDF]

open access: yes, 2013
Aminoanthraquinones were successfully synthesized via two reaction steps. 1,4-Dihydroxyanthraquinone (1) was first subjected to methylation, reduction and acylation to give an excellent yield of anthracene-1,4-dione (3), 1,4-dimethoxyanthracene-9,10 ...
Barnard   +12 more
core   +2 more sources

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh   +4 more
wiley   +1 more source

The analysis of the proliferative activity of cells on microparticles obtained from decellularized liver and kidney tissue

open access: yesВестник трансплантологии и искусственных органов, 2019
Aim. To develop the protocols for liver and kidney tissue decellularization, and to develop an analysis of the proliferative activity of human Hep-G2 hepatocarcinoma cells on various carriers.Materials and methods.
M. M. Bobrova   +4 more
doaj   +1 more source

Modulation of succinate transport in Hep G2 cell line by PKC

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2007
The cellular uptake of the tricarboxylic acid cycle (TCA) intermediates is very important for cellular metabolism. However, the transport pathways for these intermediates in liver cells are not well characterized. We have examined the transport of succinate and citrate in the human hepatoma cell line Hep G2 and found that it exhibited a higher rate of ...
Srisawang, Piyarat   +2 more
openaire   +2 more sources

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

open access: yesThe FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio   +12 more
wiley   +1 more source

Cytotoxic activity of Ecballium elaterium fruit extract on three cancer cell lines [PDF]

open access: yes
Introduction: Cancer is a common cause of mortality in all of the world specifically in middle age and elderly people. The prevalence of cancer is growing up because the lifetime is going up. In consequence finding on effective treatment for cancer is a
بهلولی, شهاب   +2 more
core  

In vitro evaluation of the comprehensive antimicrobial and antioxidant properties of Curtisia dentata (Burm.f) C.A. Sm: toxicological effect on the human embryonic kidney (HEK293) and human hepatocellular carcinoma (HepG2) cell lines [PDF]

open access: yes, 2015
Curtisia dentata is used in African traditional medicine to treat variety of infections. C. dentata leaves were collected from Buffelskloof Nature Reserve, South Africa.
Fadipe, VO, Mongalo, NI, Opoku, AR
core   +1 more source

Frequently Reported Blood Biomarkers in Sarcopenia Clinical Trials: A Systematic Review and Meta‐Analysis

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This systematic review and meta‐analysis identifies blood‐based biomarkers (BBMs) reported in sarcopenia trials, investigating the impact of sarcopenia interventions on BBMs concentrations. Significant heterogeneity was observed in sarcopenia outcomes. Interventions had a limited impact on BBMs, except for IGF‐1, which was significantly impacted by the
Emma Calluy   +10 more
wiley   +1 more source

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