Results 81 to 90 of about 28,532 (228)
Pain Practice, Volume 26, Issue 5, June 2026.ABSTRACT Objectives Low back pain is a common pathology in the general population. In people over 60 years of age, it is associated with degenerative changes that cause narrowing of the vertebral canal. Its treatment includes conservative measures and even surgery with decompression and fusion.
Juan Carlos Acevedo‐Gonzalez +3 more
wiley +1 more source
Epigenetics, 2020 Estrogen (E2) regulates hundreds of genes involved in cell metabolism and disrupts iron homoeostasis in various cell types. Herein, we addressed whether E2-induced epigenetic modifications are involved in modulating the expression of iron-regulatory ...
Jibran Sualeh Muhammad +3 more
doaj +1 more source
Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells. [PDF]
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology, 1994 Cytokines, important biochemical mediators of inflammation, cause a rapid fall in the plasma concentration of cholesterol in vivo. One mechanism by which cytokines may cause acquired hypocholesterolemia is by decreasing the hepatic synthesis and secretion of apolipoproteins.
W H, Ettinger +6 more
openaire +2 more sources
Advanced Science, Volume 13, Issue 25, 4 May 2026.The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo +8 more
wiley +1 more source
Cytotoxic activity of Ecballium elaterium fruit extract on three cancer cell lines [PDF]
Introduction: Cancer is a common cause of mortality in all of the world specifically in middle age and elderly people. The prevalence of cancer is growing up because the lifetime is going up. In consequence finding on effective treatment for cancer is a
بهلولی, شهاب +2 more
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Graphene oxide nanoribbons induce autophagic vacuoles in neuroblastoma cell lines [PDF]
, 2016 Since graphene nanoparticles are attracting increasing interest in relation to medical applications, it is important to understand their potential effects on humans. In the present study, we prepared graphene oxide (GO) nanoribbons by oxidative unzipping
Fico, Flavia +7 more
core +2 more sources
Advanced Science, Volume 13, Issue 25, 4 May 2026.A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu +6 more
wiley +1 more source
Cell micropatterning inside a microchannel and assays under a stable concentration gradient [PDF]
, 2010 We describe the use of a microfluidic device to micropattern cells in a microchannel and investigated the behavior of these cells under a concentration gradient.
Fukuda Junji +6 more
core +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song +4 more
wiley +1 more source
NUOVI DERIVATI 2-ACETAMMIDOBENZAMMIDICI: ATTIVITÀ ANTIPROLIFERATIVA E POSSIBILE MECCANISMO DI AZIONE [PDF]
, 2014 Le cinnammido benzammidi rappresentano una classe di sostanze biologicamente attive di grande interesse farmaceutico. Nonostante siano state descritte per svariate attività biologiche, nessun dato è stato riportato sulla loro attivita antitumorale ...
Bai, R +7 more
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