Results 91 to 100 of about 28,532 (228)

Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action [PDF]

open access: yes, 2019
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable.
Arizza V.   +4 more
core   +1 more source

Modulation of succinate transport in Hep G2 cell line by PKC

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2007
The cellular uptake of the tricarboxylic acid cycle (TCA) intermediates is very important for cellular metabolism. However, the transport pathways for these intermediates in liver cells are not well characterized. We have examined the transport of succinate and citrate in the human hepatoma cell line Hep G2 and found that it exhibited a higher rate of ...
Srisawang, Piyarat   +2 more
openaire   +2 more sources

Cryptocaryone Exhibits ROS/MAPK‐Dependent Antiproliferative and Apoptosis‐Inducing Effects on Triple‐Negative Breast Cancer Cells and Proof‐of‐Concept Breast Cancer Mouse Model

open access: yesDrug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Omics’ technologies have enabled clinicians to gain previously unprecedented insights into the molecular complexity and clinical heterogeneity of triple‐negative breast cancer (TNBC). Increasingly it is being realized that TNBC does not respond well to current targeted therapies.
Ya‐Ting Chuang   +6 more
wiley   +1 more source

Extended-release niacin increases anti-apolipoprotein A-I antibodies that block the antioxidant effect of high-density lipoprotein-cholesterol: the EXPLORE clinical trial. [PDF]

open access: yes, 2017
Extended-release niacin (ERN) is the most effective agent for increasing high-density lipoprotein-cholesterol (HDL-C). Having previously identified anti-HDL antibodies, we investigated whether ERN affected the antioxidant capacity of HDL and whether ERN ...
Alves, JD   +6 more
core   +1 more source

Temperature Dependence of Paramagnetic Species in the Human Brain Tissue: An X‐Band EPR Study

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 5, Page 3031-3043, May 2026.
ABSTRACT Purpose Paramagnetic ions are distributed throughout the human brain. The increased accumulation of these metals, such as iron and copper, can induce cellular death and the development of neurological diseases. Electron Paramagnetic Resonance (EPR) is a spectroscopic technique capable of detecting these ions in a given biological sample ...
André Avanzine   +6 more
wiley   +1 more source

The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects [PDF]

open access: yes, 2017
Este es el manuscrito que fue aceptado y que finalmente se publicó en Cancer Letters con el DOI: 10.1016/j.canlet.2016.10.037The natural bioactive compound damnacanthal inhibits several tyrosine kinases.
García-Vilas, Javier A.   +4 more
core  

Characterization of the carboxypeptidase N secreted by Hep G2 cells.

open access: yesJournal of Biological Chemistry, 1988
Human hepatoma (Hep G2) cells secrete nanogram quantities of carboxypeptidase enzymes which are capable of hydrolyzing COOH-terminal lysine and arginine residues. A carboxypeptidase with a neutral pH optimum (greater than pH 7.0) was partially purified from the conditioned medium and compared with pure plasma carboxypeptidase N. The two enzymes behaved
B G, Grimwood   +2 more
openaire   +2 more sources

Time‐resolved XPCS analysis across broad time‐scales using multi‐tau two‐time correlations

open access: yesJournal of Synchrotron Radiation, Volume 33, Issue 3, Page 698-707, May 2026.
A scalable multi‐tau two‐time correlation framework enables efficient, time‐resolved XPCS analysis of long duration high‐frame‐rate modern synchrotron data while preserving sensitivity to non‐stationary dynamics.We present a multi‐tau two‐time correlation (MT‐2TC) analysis for X‐ray photon correlation spectroscopy that enables efficient analysis of ...
Fabio Brugnara   +13 more
wiley   +1 more source

Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and application in food [PDF]

open access: yes, 2018
Ochratoxin A (OTA) is one of the main mycotoxins that can be found in food. The use of gamma radiation is a technique for preserving food that may exert some effects on mycotoxins.
Abrunhosa, Luís   +4 more
core   +1 more source

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