Induction of propranolol metabolism in the Hep G2 human hepatoma cell line
Journal of Pharmacy and Pharmacology, 1992 Abstract Metabolism of propranolol by the human hepatoma cell line Hep G2 was studied. Although metabolism qualitatively was similar to that in-vivo, the P450-mediated N-desisopropylation clearly predominated. Pretreatment of cells with 3-methylcholanth-rene increased the activity of this pathway 14-fold, whereas phenobarbitone had no ...
A, Steiner, U K, Walle, T, Walle
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Requirement of Activation for Hepatitis B Virus Infection [PDF]
, 2007 Although _in vitro_ models of human hepatitis B virus replication are established, so far none could approximate infection efficiency as expected from _in vivo_ observations.
Claudia Maenz, Michael Bruns
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New palladium and platinum complexes with bioactive 3,5-diacetyl-1,2,4- triazol bis(4-cyclohexyl thiosemicarbazone) ligand: Chemistry, antiproliferative activity and preliminary toxicity studies [PDF]
, 2012 Dalton Transactions 41.40 (2012): 12538-12547. Reproduced by permission of The Royal Society of ChemistryThe preparation and characterization of the new 3,5-diacetyl-1,2,4-triazol bis(4-cyclohexyl thiosemicarbazone) ligand, H5L1, is described.
Matesanz, Ana I. +2 more
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Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation.
Journal of Lipid Research, 1988 Apolipoprotein B is the principal protein associated with cholesterol transport in the blood and has been proposed to play a central role in human atherogenesis.
J M Hoeg +5 more
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Influence of hyperhomocysteinemia on the cellular redox state - Impact on homocysteine-induced endothelial dysfunction [PDF]
, 2003 Hyperhomocysteinemia is an independent risk factor for the development of atherosclerosis. An increasing body of evidence has implicated oxidative stress as being contributory to homocysteines deleterious effects on the vasculature.
Adachi T +29 more
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Cytotoxicity of methylsulfonylmethane (MSM) on esophageal cancer cell line (KYSE30 [PDF]
Introduction: Esophageal cancer is a relatively rare form of cance Esophageal cancer have been considered as a chemosensitive tumors for many years. Methylsulfonylmethane MSM) is an organic formof sulfur that can be dietary supplement to support proper
بهلولی, شهاب +1 more
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Targeted Stimuli-Responsive Dextran Conjugates for Doxorubicin Delivery to Hepatocytes [PDF]
, 2006 A targeted, stimuli-responsive, polymeric drug delivery vehicle has been developed to help alleviate the severe side-effects caused by narrow therapeutic window drugs. Doxorubicin, a commonly used chemotherapeutic agent has been conjugated to dextran by
Joshi, Shilpa M. +3 more
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Glypican-3 Targeting of Liver Cancer Cells Using Multifunctional Nanoparticles
Molecular Imaging, 2011 Imaging is essential in accurately detecting, staging, and treating primary liver cancer (hepatocellular carcinoma [HCC]), one of the most prevalent and lethal malignancies.
James O. Park +8 more
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Anti-Hypercholesterolemia Effects of Edible Seaweed Extracts and Metabolomic Changes in Hep-G2 and Caco-2 Cell Lines. [PDF]
Life (Basel), 2023 Coelho M, Pacheco R.
europepmc +1 more source
Ekstrak Etanolik Herba Ciplukan (Physalis Angulata L.) Berefek Sitotoksik dan Menginduksi Apoptosis pada Sel Kanker Payudara Mcf-7 [PDF]
, 2011 Potensi sitotoksik Ciplukan (Physalis angulata L.) dan kemampuannya memacu apoptosis pada beberapa sel kanker perlu diteliti. Untuk itu, ekstrak etanol herba ciplukan (EC) diaplikasikan pada sel kanker payudara MCF-7 untuk mengetahui pengaruhnya terhadap
Armandari, I. (I) +4 more
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