Results 91 to 100 of about 20,741 (247)

Primary hepatocytes as targets for hepatitis C virus replication [PDF]

, 2008
Much of our current understanding of hepatitis C virus (HCV) replication has hailed from the use of a small number of cloned viral genomes and transformed hepatoma cell lines.
Agnello, Andre, Andreo, Bartenschlager, Bartosch, Bartosch, Bartosch, Basu, Bertaux, Castet, Catanese, Chang, Cocquerel, Codran, Decaens, Diaz, Dreux, Evans, Flint, Fournier, Furuse, Gastaminza, Grove, Harder, Harris, Hsu, Huang, Kanda, Kapadia, Krieger, Lazaro, Levy, Lindenbach, Lindenbach, Maillard, Martin, McCaughan, Mee, Meertens, Mercer, Meuleman, Meunier, Moghe, Molina, Molina, Morikawa, Nielsen, Nielsen, Olenina, Pileri, Prince, Reynolds, Scarselli, Silver, Thomssen, Timpe, Vinken, Voisset, Wakita, Wang, Wunschmann, Yang, Zeisel, Zhang, Zheng, Zhong   +65 more
core   +2 more sources

From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis

Microbial Biotechnology, Volume 18, Issue 7, July 2025.
Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley   +1 more source

NF90 Binds the Dengue Virus RNA 3′ Terminus and is a Positive Regulator of Dengue Virus Replication [PDF]

, 2010
Background Viral RNA translation and replication are regulated by sequence and structural elements in the 5′ and 3′ untranslated regions (UTR) and by host cell and/or viral proteins that bind them.
A Agarwal, A Kaminski, AA Khromykh, AM Parrott, B Tassaneetrithep, BJ Calnan, CJ Chen, CR Lambeth, CW Davis, D Guan, DE Alvarez, DE Alvarez, DJ Gubler, DN Perkins, F Houser-Scott, F Vumbaca, Glover W. Martin, HJ Liao, I Pfeifer, J Heukelbach, J Shim, JA Dibbens, JC Larcher, JL Blackwell, JL Blackwell, JM Ruijter, JW Balliet, KL Holden, KL Holden, Kylene Kehn-Hall, L Shi, L Yu, L Zeng, Lee Gehrke, LR Saunders, M Bray, M De Nova-Ocampo, M Tilgner, MA Brinton, MK Merrill, MW Pfaffl, O Isken, O Isken, P Lawrence, PJ Bredenbeek, PR Baker, PR Copeland, R Deng, R Men, Raúl C. Gomila, S Elghonemy, S Sakamoto, S You, SA Jobling, SM Paranjape, SS Whitehead, T Grange, T Ito, TP Monath, WG Davis   +59 more
core   +6 more sources

Evaluation of ribavirin efficacy and tolerance in subjects with chronic hepatitis C virus infection [PDF]

Vojnosanitetski Pregled, 2002
Background. Reports by hepatologists indicated that anti-HCV antibodies might be detected in 71% to 84% of cases of post-transfusion hepatitis and in up to 50% of cases of sporadic non-A non-B hepatitis.
Stanimirović Violeta, Nikolić Dejan, Stanimirović Branko, Nikolić Aleksandra, Čučak Spomenka   +4 more
doaj   +1 more source

Pathogenesis, MicroRNA‐122 Gene‐Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection

Hepatology, 2021
Equine hepacivirus (EqHV) is phylogenetically the closest relative of HCV and shares genome organization, hepatotropism, transient or persistent infection outcome, and the ability to cause hepatitis.
J. Tomlinson, Raphael Wolfisberg, U. Fahnøe, Roosheel S. Patel, Sheetal Trivedi, Arvind Kumar, Himanshu Sharma, Louise Nielsen, S. McDonough, J. Bukh, B. Tennant, A. Kapoor, Brad R. Rosenberg, C. Rice, T. Divers, G. R. Van de Walle, T. Scheel   +16 more
semanticscholar   +1 more source

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi, Asiyeh Jebelli, Parisa Shiri Aghbash, Behzad Baradaran, Mohammad Amini, Fatemeh Oroojalian, Nasser Pouladi, Hossein Bannazadeh Baghi, Miguel de la Guardia, Amir Ali Mokhtarzadeh   +9 more
wiley   +1 more source

Protein Interactions during the Flavivirus and Hepacivirus Life Cycle

Molecular & Cellular Proteomics, 2017
Protein-protein interactions govern biological functions in cells, in the extracellular milieu, and at the border between cells and extracellular space. Viruses are small intracellular parasites and thus rely on protein interactions to produce progeny inside host cells and to spread from cell to cell.
Gerold, Gisa, Bruening, Janina, Weigel, Bettina, Pietschmann, Thomas   +3 more
openaire   +4 more sources

Association of oral lichen planus with hepatitis C virus, surface antigen of hepatitis B virus, and diabetes: A clinical and biochemical study

Journal of Indian Academy of Oral Medicine and Radiology, 2016
Background: Oral lichen planus is an inflammatory mucocutaneous disease commonly encountered in the dental clinic. The etiology of oral lichen planus is still unknown.
Pavani Donempudi, Harsha Bhayya, Venkateswarlu Meduri, Geetha Paramkusam, Avinash M L Tejasvi   +4 more
doaj   +1 more source

Natural co‐infection of divergent hepatitis B and C virus homologues in carnivores [PDF]

, 2021
In humans, co-infection of hepatitis B and C viruses (HBV, HCV) is common and aggravates disease outcome. Infection-mediated disease aggravation is poorly understood, partly due to lack of suitable animal models. Carnivores are understudied for hepatitis
Aguilar‐Setién, Álvaro, Alfonso‐Toledo, Jorge A., Almazan‐Marin, Cenia, Brünink, Sebastian, Carvalho‐Urbieta, Victor, Drexler, Jan Felix, Galvez‐Romero, Guillermo, García‐Baltazar, Anahí, Glebe, Dieter, Jo, Wendy K., Kühne, Arne, Obregón‐Morales, Cirani, Rasche, Andrea, Rendón‐Franco, Emilio, Salas‐Rojas, Monica   +14 more
core   +1 more source

[The analysis of immunoreactivity of individual B-cell epitopes of hepatitis C virus (Flaviviridae: Hepacivirus: Hepatitis С virus) NS4a antigen].

Voprosy virusologii, 2022
INTRODUCTION Chronic viral hepatitis C (CHC) is a ubiquitous infectious disease, a significant limitation of which WHO attributes to the use of a new highly effective antiviral therapy.
L. I. Nikolaeva, A. N. Belyavtsev, N. Shevchenko, M. D. Stuchinskaya, E. Samokhvalov, A. Dedova, G. V. Sapronov, N. Shastina, V. V. Kuprianov   +8 more
semanticscholar   +1 more source