Results 71 to 80 of about 42,842 (184)

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Non-primate hepacivirus infection with apparent hepatitis in a horse — Short communication

, 2014
Non-primate hepacivirus (NPHV) is a recently identified hepacivirus (family Flaviviridae) in dog and horse; however, the disease associations remain unknown.
Maza, Norbert, Norbert Maza, Boros, Ákos, Gábor Reuter, Reuter, Gábor, Pankovics, Péter, Péter Pankovics, Ákos Boros   +7 more
core   +1 more source

Hepatic immunopathology during occult hepacivirus re-infection

Virology, 2017
Despite drug advances for Hepatitis C virus (HCV), re-infections remain prevalent in high-risk populations. Unfortunately, the role of preexisting viral immunity and how it modulates re-infection is unclear. GBV-B infection of common marmosets is a useful model to study tissue immune responses in hepacivirus infections, and in this study we re ...
Cordelia, Manickam, Amanda J, Martinot, Rhianna A, Jones, Valerie, Varner, R Keith, Reeves   +4 more
openaire   +2 more sources

Nonprimate Hepaciviruses in Domestic Horses, United Kingdom

Emerging Infectious Diseases, 2012
Although the origin of hepatitis C virus infections in humans remains undetermined, a close homolog of this virus, termed canine hepacivirus (CHV) and found in respiratory secretions of dogs, provides evidence for a wider distribution of hepaciviruses in
Sinéad Lyons, Amit Kapoor, Colin Sharp, Bradley S. Schneider, Nathan D. Wolfe, Geoff Culshaw, Brendan Corcoran, Bruce C. McGorum, Peter Simmonds   +8 more
doaj   +1 more source

Analysis of a Mathematical Model on the Dynamics of TB–HCV Coinfection With Medication

Journal of Applied Mathematics, Volume 2026, Issue 1, 2026.
This study employs a deterministic model that describes the combined dynamics of TB and HCV aimed at determining the impact of medication in the management of TB–HCV coinfection. The analytical and numerical analyses indicate that if the TB–HCV coinfection effective reproduction number is less than unity, the absence of both TB and HCV infections ...
Kizito Mohammed, Hasifa Nampala, Pius Ariho, Theodore Simos   +3 more
wiley   +1 more source

Association of oral lichen planus with hepatitis C virus, surface antigen of hepatitis B virus, and diabetes: A clinical and biochemical study

Journal of Indian Academy of Oral Medicine and Radiology, 2016
Background: Oral lichen planus is an inflammatory mucocutaneous disease commonly encountered in the dental clinic. The etiology of oral lichen planus is still unknown.
Pavani Donempudi, Harsha Bhayya, Venkateswarlu Meduri, Geetha Paramkusam, Avinash M L Tejasvi   +4 more
doaj   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Chronic equine hepacivirus infection in an adult gelding with severe hepatopathy [PDF]

Veterinary Medicine and Science, 2019
AbstractBackground: Equine hepacivirus (EqHV) in equids represents the closest homologue to hepatitis C virus (HCV) infecting humans. A majority ofHCVinfected patients develop a chronic course of infection leading to liver fibrosis, cirrhosis and liver failure. However, in horses mostly transient mild subclinical infections are reported for EqHVto date.
Birthe Tegtmeyer, Julia Echelmeyer, Vanessa M. Pfankuche, Christina Puff, Daniel Todt, Nicole Fischer, Andy Durham, Karsten Feige, Wolfgang Baumgärtner, Eike Steinmann, Jessika‐M. V. Cavalleri   +10 more
openaire   +4 more sources

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Identification of equine hepacivirus infections in France: Facts and Physiopathological insights

, 2016
International audienceHepatitis C virus (HCV) is one of the main causes of end stage liver diseases (cirrhosis and hepatocellular carcinoma) in humans. In vivo studies have been hampered by a lack of access to relevant animal models.
Fortier, G., Fortier, Guillaume, Saunier, B., Fortier, Christine, Foursin, M., Fortier, C., Hue, Erika, Desbrosse, F., Rey, F., Pronost, Stéphane, Pitel, Pierre-Hugues, Hue, E., Pitel, P.-H., Pronost, S.   +13 more
core   +1 more source