Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Protein Interactions during the Flavivirus and Hepacivirus Life Cycle
Protein-protein interactions govern biological functions in cells, in the extracellular milieu, and at the border between cells and extracellular space. Viruses are small intracellular parasites and thus rely on protein interactions to produce progeny inside host cells and to spread from cell to cell.
Gerold, Gisa +3 more
openaire +3 more sources
Development of diagnostic methods and study of the immunoreactivity of a mixture of recombinant core and E2 proteins fused to GST with control serum positive for hepatitis C [PDF]
The hepatitis C virus (HCV) is an enveloped virus that is about 50–70nm in diameter, has positive-strand RNA, and belongs to the genus Hepacivirus and the family Flaviridae.
Kenfe, Flávia Regina +5 more
core +1 more source
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun +10 more
wiley +1 more source
A highly divergent hepacivirus-like flavivirus in domestic ducks
Using random amplification and reverse transcription-PCR, a novel RNA virus was detected in sera of domestic ducks. The full genome of the virus was determined for three strains, identifying the first hepacivirus-like flavivirus in birds. The virus, that we tentatively named duck hepacivirus-like virus (DuHV), possesses several unique molecular ...
Lili Chu +4 more
openaire +2 more sources
Further Evidence for in Utero Transmission of Equine Hepacivirus to Foals [PDF]
(1) Background: Equine hepacivirus (EqHV), also referred to as non-primate hepacivirus (NPHV), infects horses—and dogs in some instances—and is closely related to hepatitis C virus (HCV) that has infected up to 3% of the world’s human population, causing an epidemic of liver cirrhosis and cancer.
Pronost, Stéphane +8 more
openaire +4 more sources
The occurrence of liver steatosis in patients with chronic hepatitis C - the experience of the Clinical Center of Vojvodina [PDF]
Background/Aim. Hepatic steatosis in patients with chronic hepatitis C occurs in about half of the cases. Its occurrence is influenced by factors of the host and viral factors and its importance lies in the fact that it reduces the success of antiviral ...
Preveden Tomislav +4 more
doaj +1 more source
Comparative evaluation of the total hepatitis C virus core antigen, branched-DNA, and amplicor monitor assays in determining viremia for patients with chronic hepatitis C during interferon plus ribavirin combination therapy. [PDF]
An assay prototype designed to detect and quantify total hepatitis C virus [HCV] core antigen (HCV core Ag) protein in serum and plasma in the presence or absence of anti-HCV antibodies has been recently developed by Ortho-Clinical Diagnostics.
P. Veillon +5 more
core +2 more sources
ABSTRACT No laboratory test performed to date provides an absolute guarantee for detecting infectious agents. Nucleic acid amplification techniques/tests (NAT) associated with serological tests can increase safety and provide greater diagnostic accuracy for patients. We investigated the added safety of NAT technology combined with serological tests for
Heloise Skiavine Madeira +14 more
wiley +1 more source
Modeling HCV disease in animals: virology, immunology and pathogenesis of HCV and GBV-B infections [PDF]
Hepatitis C virus (HCV) infection has become a global public health burden costing billions of dollars in health care annually. Even with rapidly advancing scientific technologies this disease still poses a significant threat due to a lack of vaccines ...
Manickam, Cordelia, Reeves, R. Keith
core +2 more sources

