Results 71 to 80 of about 44,632 (248)

Acute and chronic infections with nonprimate hepacivirus in young horses [PDF]

open access: yesVeterinary Research, 2016
The recently discovered nonprimate hepacivirus (NPHV) naturally infects horses and is the closest known homolog of hepatitis C virus to date. Within a follow-up study acute field infections were monitored in four young Thoroughbred horses until the ages of 12-13 months.
Gather, Theresa   +6 more
openaire   +4 more sources

Animal hepacivirus models for hepatitis C virus immune responses and pathology [PDF]

open access: bronzeJournal of Hepatology
Matthew J. Kennedy   +2 more
openalex   +2 more sources

Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals [PDF]

open access: yes, 2018
INTRODUCTION: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually.
Petruzziello, Arnolfo   +5 more
core   +1 more source

Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection

open access: yesPLoS Pathogens, 2023
Immune correlates of hepatitis C virus (HCV) clearance and control remain poorly defined due to the lack of an informative animal model. We recently described acute and chronic rodent HCV-like virus (RHV) infections in lab mice.
Piyush Dravid   +14 more
semanticscholar   +1 more source

Flunarizine arrests hepatitis C virus membrane fusion. [PDF]

open access: yes, 2015
Written with support from a Senior Research Fellowship from the Wellcome Trust (grant no.: 101908/Z/13/Z) to Y.M. and from grant R01 GM102869 from the National Institutes of Health to Y.M.This is the author accepted manuscript.
Didigu   +9 more
core   +1 more source

Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam

open access: yesViruses, 2018
Rodents and bats are now widely recognised as important sources of zoonotic virus infections in other mammals, including humans. Numerous surveys have expanded our knowledge of diverse viruses in a range of rodent and bat species, including their origins,
Dung Van Nguyen   +10 more
doaj   +1 more source

Persistent hepatitis C virus infection in vitro: coevolution of virus and host. [PDF]

open access: yes, 2006
The virological and cellular consequences of persistent hepatitis C virus (HCV) infection have been elusive due to the absence of the requisite experimental systems.
Cheng, Guofeng   +7 more
core   +3 more sources

Identification of a Novel Hepacivirus in Domestic Cattle from Germany [PDF]

open access: yesJournal of Virology, 2015
ABSTRACT Hepatitis C virus (HCV) continues to represent one of the most significant threats to human health. In recent years, HCV-related sequences have been found in bats, rodents, horses, and dogs, indicating a widespread distribution of hepaciviruses among animals. By applying unbiased high-throughput sequencing, a novel virus
Christine, Baechlein   +11 more
openaire   +2 more sources

Evolution and Diversity of Hepatitis C Virus and Peculiarity of Modern Laboratory Diagnostic of Hepatitis C Markers

open access: yesЭпидемиология и вакцинопрофилактика, 2015
Hepatitis C virus (HCV), which was identified in 1989 - 1990. Later it was included in new genus Hepacivirus of the family Flaviviridae. Due the genetic heterogeneity of HCV, viral isolates was decided to classificate on genotypes and sybtypes in ...
L. I. Nikolaeva   +2 more
doaj   +1 more source

Refractory Hepatic Hydrothorax in Chronic Hepatitis C Controlled by Direct-acting Antivirals

open access: yesThe Korean Journal of Gastroenterology, 2020
Hepatic hydrothorax is a transudative pleural effusion that complicates advanced liver cirrhosis. Patients refractory to medical treatment plus salt restriction and diuretics are considered to have refractory hepatic hydrothorax and may require ...
Myung Hee Kim   +5 more
doaj   +1 more source

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