Results 71 to 80 of about 43,714 (247)

Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]

open access: yes, 2009
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter   +5 more
core   +2 more sources

Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy [PDF]

open access: yes, 2013
BACKGROUND: Noninvasive methods for liver fibrosis evaluation in chronic liver diseases have been recently developed, i.e. transient elastography (Fibroscan™) and blood tests (Fibrometer®, Fibrotest®, and Hepascore®).
ANRS HCEP 23 Fibrostar Group   +12 more
core   +2 more sources

Genome Characterization and Phylogenetic Analysis of Bovine Hepacivirus in Inner Mongolia, Northeastern China

open access: yesZoonoses, 2022
Bovine hepacivirus (BovHepV) is a new member of the genus Hepacivirus in the family Flaviviridae, which has been detected in cattle in more than seven countries.
Zi-Jiang Liu   +12 more
semanticscholar   +1 more source

Characterization of nonprimate hepacivirus and construction of a functional molecular clone [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance The origin of hepatitis C virus (HCV) has long remained a mystery. Unexpectedly, a plethora of HCV-related hepaciviruses was recently discovered in horses, monkeys, rodents, and bats. These discoveries are of particular interest and may aid in understanding HCV evolution, molecular biology, and natural history.
Meigang Gu   +16 more
openaire   +4 more sources

Evolution and Diversity of Hepatitis C Virus and Peculiarity of Modern Laboratory Diagnostic of Hepatitis C Markers

open access: yesЭпидемиология и вакцинопрофилактика, 2015
Hepatitis C virus (HCV), which was identified in 1989 - 1990. Later it was included in new genus Hepacivirus of the family Flaviviridae. Due the genetic heterogeneity of HCV, viral isolates was decided to classificate on genotypes and sybtypes in ...
L. I. Nikolaeva   +2 more
doaj   +1 more source

Delayed by Design: Role of Suboptimal Signal Peptidase Processing of Viral Structural Protein Precursors in Flaviviridae Virus Assembly

open access: yesViruses, 2020
The Flaviviridae virus family is classified into four different genera, including flavivirus, hepacivirus, pegivirus, and pestivirus, which cause significant morbidity and mortality in humans and other mammals, including ruminants and pigs.
Nabeel Alzahrani   +3 more
doaj   +1 more source

Flunarizine arrests hepatitis C virus membrane fusion. [PDF]

open access: yes, 2015
Written with support from a Senior Research Fellowship from the Wellcome Trust (grant no.: 101908/Z/13/Z) to Y.M. and from grant R01 GM102869 from the National Institutes of Health to Y.M.This is the author accepted manuscript.
Didigu   +9 more
core   +1 more source

Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam

open access: yesViruses, 2018
Rodents and bats are now widely recognised as important sources of zoonotic virus infections in other mammals, including humans. Numerous surveys have expanded our knowledge of diverse viruses in a range of rodent and bat species, including their origins,
Dung Van Nguyen   +10 more
doaj   +1 more source

Collaborative Referral Model to Achieve Hepatitis C Micro-Elimination in Methadone Maintenance Treatment Patients during the COVID-19 Pandemic

open access: yesViruses, 2022
Although hepatitis C virus (HCV) prevails in patients receiving methadone maintenance treatment (MMT), most do not receive anti-HCV therapy. This single-center observational study aimed to achieve HCV micro-elimination at an MMT center during the COVID ...
Chi-Ming Tai   +13 more
doaj   +1 more source

Persistent hepatitis C virus infection in vitro: coevolution of virus and host. [PDF]

open access: yes, 2006
The virological and cellular consequences of persistent hepatitis C virus (HCV) infection have been elusive due to the absence of the requisite experimental systems.
Cheng, Guofeng   +7 more
core   +3 more sources

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