Results 71 to 80 of about 17,555 (155)

Heparan sulfate proteoglycans mediate prion-like α-synuclein toxicity in Parkinson's in vivo models. [PDF]

Life Sci Alliance, 2022
Chen M, Vincent J, Ezeanii A, Wakade S, Yerigenahally S, Mor DE.   +5 more
europepmc   +1 more source

Associations of intra‐pancreatic fat deposition with triglyceride‐rich lipoproteins and lipoprotein lipase

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3233-3241, June 2025.
Abstract Aims To investigate the associations of intra‐pancreatic fat deposition (IPFD) with very‐low‐density lipoprotein (VLDL), intermediate‐density lipoprotein (IDL) and lipoprotein lipase. Materials and methods A total of 174 participants underwent magnetic resonance imaging on a 3.0 Tesla scanner for the quantification of IPFD.
Yutong Liu, Loren Skudder‐Hill, Wandia Kimita, Xiatiguli Shamaitijiang, Ivana R. Sequeira‐Bisson, Maxim S. Petrov   +5 more
wiley   +1 more source

Infection and transmission of SARS-CoV-2 depend on heparan sulfate proteoglycans. [PDF]

EMBO J, 2021
Bermejo-Jambrina M, Eder J, Kaptein TM, van Hamme JL, Helgers LC, Vlaming KE, Brouwer PJM, van Nuenen AC, Spaargaren M, de Bree GJ, Nijmeijer BM, Kootstra NA, van Gils MJ, Sanders RW, Geijtenbeek TBH.   +14 more
europepmc   +1 more source

Recent Advances in Enzymes and Chemoenzymatic Synthesis of Tetrasaccharide Linkage Region of Proteoglycans

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
The tetrasaccharide linkage region of proteoglycans is synthesized through a series of well‐controlled enzymatic reactions in nature. The expression, activity, and substrate profile of these biosynthetic enzymes and the latest development of chemoenzymatic synthesis of linkage region‐bearing glycopeptides are summarized in this review.
Po‐han Lin, Xuefei Huang
wiley   +1 more source

Pericellular heparan sulfate proteoglycans: Role in regulating the biosynthetic response of nucleus pulposus cells to osmotic loading. [PDF]

JOR Spine, 2022
Krull CM, Rife J, Klamer B, Purmessur D, Walter BA.   +4 more
europepmc   +1 more source

First Steps toward the Design of Peptides that Influence the Intracellular Palmitoylation Machinery

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
Herein, DC peptides consisting of the cell‐penetrating peptide sC18* and a Asp–His–His–Cys (DHHC) motif derived from human ZDHHC palmitoyltransferase are highlighted. DC peptides demonstrate high cellular internalization into various cellular models, exert cytotoxic effects against cancerous cells, and alter the function and localization of known ...
Katharina Stillger, Eric Platz‐Baudin, Florian Friedland, Melina Ruppel, Coco‐Louisa Sticker, Anne Bodenhausen, Erik Noetzel, Ines Neundorf   +7 more
wiley   +1 more source

Heparan Sulfate Proteoglycans as Attachment Factor for SARS-CoV-2. [PDF]

ACS Cent Sci, 2021
Liu L, Chopra P, Li X, Bouwman KM, Tompkins SM, Wolfert MA, de Vries RP, Boons GJ.   +7 more
europepmc   +1 more source

Scientific approaches to defining HPV vaccine‐induced protective immunity

International Journal of Cancer, Volume 156, Issue 10, Page 1848-1857, 15 May 2025.
Abstract Seventeen years after the licensure of prophylactic human papillomavirus (HPV) L1 virus‐like‐particle vaccines, a defined antibody level that correlates with vaccine‐induced protection against HPV infections and associated neoplasia is missing.
Matti Lehtinen, Pierre van Damme, Simon Beddows, Ligia A. Pinto, Filipe Mariz, Penelope Gray, Joakim Dillner   +6 more
wiley   +1 more source

Heparan sulfate proteoglycans serve as alternative receptors for low affinity LCMV variants. [PDF]

PLoS Pathog, 2021
Volland A, Lohmüller M, Heilmann E, Kimpel J, Herzog S, von Laer D.   +5 more
europepmc   +1 more source

The Unifying Hypothesis of Alzheimer's Disease: Heparan Sulfate Proteoglycans/Glycosaminoglycans Are Key as First Hypothesized Over 30 Years Ago. [PDF]

Front Aging Neurosci, 2021
Snow AD, Cummings JA, Lake T.
europepmc   +1 more source