Results 1 to 10 of about 190,021 (170)

Heparin, Low Molecular Weight Heparin, and Non-Anticoagulant Derivatives for the Treatment of Inflammatory Lung Disease [PDF]

open access: yesPharmaceuticals, 2023
Unfractionated heparin has multiple pharmacological activities beyond anticoagulation. These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low molecular weight and non-anticoagulant heparin derivatives.
Janis Kay Shute
doaj   +2 more sources

Poly(dimethylsiloxane)-poly(ethyleneoxide)-heparin block copolymers. I. Synthesis and characterization [PDF]

open access: yes, 1988
Amphiphilic block copolymers containing poly(dimethylsiloxane), poly(ethylene oxide), and heparin (PDMS-PEO-Hep) have been prepared via a series of coupling reactions using functionalized prepolymers, diisocyanates, and derivatized heparins.
Agarwal   +40 more
core   +21 more sources

LOW MOLECULAR WEIGHT HEPARINS [PDF]

open access: yesMedical Journal Armed Forces India, 1998
Low-molecular-weight heparins (LMWH) are a new group of parenteral anticoagulants. They represent a major clinical advance in anticoagulation since the identification of unfractionated heparin (UFH) in 1922 and the introduction of the synthetic coumarin derivative, warfarin, in 1948.
J N, Huang, A, Shimamura
openaire   +4 more sources

Inhibition of trypsin by heparin and dalteparin, a low molecular weight heparin [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
The interaction between trypsin, a prototype S1 serine protease, with heparin and its low molecular weight derivative dalteparin were investigated. Direct inhibition of the proteolytic activity of trypsin by heparin and dalteparin, used in concentrations
OLIVERA M. BOSNIĆ   +3 more
doaj   +3 more sources

Therapeutic inefficacy of protocol driven intravenous unfractionated heparin infusion in the current era

open access: yesAmerican Heart Journal Plus, 2023
Unfractionated heparin (UFH) is commonly used for several life-threatening conditions requiring anticoagulant therapy but failure to reach therapeutic levels in 24 h can be associated with adverse outcomes.
Kayla Torppey   +7 more
doaj   +1 more source

Low molecular weight heparin in COVID-19: benefits and concerns

open access: yesFrontiers in Pharmacology, 2023
Since its emergence, the COVID-19 pandemic had a dramatic impact on the public health worldwide and it scarred the medical, economical, and social determinants of health.
Adham Makarem   +10 more
doaj   +1 more source

The Effect of Low Molecular Weight Heparins on Placentation: A Rat Model Study

open access: yesCumhuriyet Science Journal, 2022
Low molecular weight heparins (LMWHs) have been used for the treatment for recurrent pregnancy loss (RPL) for a long time. We aimed to investigate the efficacy of the LMWHs on angiogenesis and apoptosis during placentation.
Gülizar Özer   +3 more
doaj   +1 more source

Low molecular weight heparins [PDF]

open access: yesIntensive and Critical Care Nursing, 1996
A new class of anticoagulant with advantages over standard heparin were introduced in 1990. Collectively termed low molecular weight heparins, their role is increasing in the treatment and prophylaxis of thromboembolism.
openaire   +4 more sources

Efficacy and safety of low-dose aspirin combined with low-molecular-weight heparin in treatment of preeclampsia: a meta-analysis and systematic review

open access: yesArchives of Medical Science, 2021
Introduction The role of low-dose aspirin combined with low-molecular-weight heparin (LMWH) in the treatment of preeclampsia (PE) remains unclear. We aimed to assess the efficacy and safety of low-dose aspirin combined with LMWH in PE treatment, to ...
Chunfeng Wu   +3 more
doaj   +1 more source

Low-Molecular Weight Heparin Increases Circulating sFlt-1 Levels and Enhances Urinary Elimination [PDF]

open access: yes, 2014
Rationale: Preeclampsia is a devastating medical complication of pregnancy which leads to maternal and fetal morbidity and mortality. While the etiology of preeclampsia is unclear, human and animal studies suggest that excessive circulating levels of ...
Hagmann, Henning   +10 more
core   +8 more sources

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