Results 1 to 10 of about 190,021 (170)
Heparin, Low Molecular Weight Heparin, and Non-Anticoagulant Derivatives for the Treatment of Inflammatory Lung Disease [PDF]
Unfractionated heparin has multiple pharmacological activities beyond anticoagulation. These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low molecular weight and non-anticoagulant heparin derivatives.
Janis Kay Shute
doaj +2 more sources
Poly(dimethylsiloxane)-poly(ethyleneoxide)-heparin block copolymers. I. Synthesis and characterization [PDF]
Amphiphilic block copolymers containing poly(dimethylsiloxane), poly(ethylene oxide), and heparin (PDMS-PEO-Hep) have been prepared via a series of coupling reactions using functionalized prepolymers, diisocyanates, and derivatized heparins.
Agarwal +40 more
core +21 more sources
LOW MOLECULAR WEIGHT HEPARINS [PDF]
Low-molecular-weight heparins (LMWH) are a new group of parenteral anticoagulants. They represent a major clinical advance in anticoagulation since the identification of unfractionated heparin (UFH) in 1922 and the introduction of the synthetic coumarin derivative, warfarin, in 1948.
J N, Huang, A, Shimamura
openaire +4 more sources
Inhibition of trypsin by heparin and dalteparin, a low molecular weight heparin [PDF]
The interaction between trypsin, a prototype S1 serine protease, with heparin and its low molecular weight derivative dalteparin were investigated. Direct inhibition of the proteolytic activity of trypsin by heparin and dalteparin, used in concentrations
OLIVERA M. BOSNIĆ +3 more
doaj +3 more sources
Unfractionated heparin (UFH) is commonly used for several life-threatening conditions requiring anticoagulant therapy but failure to reach therapeutic levels in 24 h can be associated with adverse outcomes.
Kayla Torppey +7 more
doaj +1 more source
Low molecular weight heparin in COVID-19: benefits and concerns
Since its emergence, the COVID-19 pandemic had a dramatic impact on the public health worldwide and it scarred the medical, economical, and social determinants of health.
Adham Makarem +10 more
doaj +1 more source
The Effect of Low Molecular Weight Heparins on Placentation: A Rat Model Study
Low molecular weight heparins (LMWHs) have been used for the treatment for recurrent pregnancy loss (RPL) for a long time. We aimed to investigate the efficacy of the LMWHs on angiogenesis and apoptosis during placentation.
Gülizar Özer +3 more
doaj +1 more source
Low molecular weight heparins [PDF]
A new class of anticoagulant with advantages over standard heparin were introduced in 1990. Collectively termed low molecular weight heparins, their role is increasing in the treatment and prophylaxis of thromboembolism.
openaire +4 more sources
Introduction The role of low-dose aspirin combined with low-molecular-weight heparin (LMWH) in the treatment of preeclampsia (PE) remains unclear. We aimed to assess the efficacy and safety of low-dose aspirin combined with LMWH in PE treatment, to ...
Chunfeng Wu +3 more
doaj +1 more source
Low-Molecular Weight Heparin Increases Circulating sFlt-1 Levels and Enhances Urinary Elimination [PDF]
Rationale: Preeclampsia is a devastating medical complication of pregnancy which leads to maternal and fetal morbidity and mortality. While the etiology of preeclampsia is unclear, human and animal studies suggest that excessive circulating levels of ...
Hagmann, Henning +10 more
core +8 more sources

