Results 1 to 10 of about 381,135 (230)

Heparin, Low Molecular Weight Heparin, and Non-Anticoagulant Derivatives for the Treatment of Inflammatory Lung Disease [PDF]

open access: yesPharmaceuticals, 2023
Unfractionated heparin has multiple pharmacological activities beyond anticoagulation. These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low molecular weight and non-anticoagulant heparin derivatives.
Janis Kay Shute
doaj   +3 more sources

Low molecular-weight heparin is better than warfarin for prevention of recurrent venous thromboembolism in cancer patients [PDF]

open access: yesNew England Journal of Medicine, 2017
A critical appraisal and clinical application of Lee AYY, Levin MN, Bake RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med. 2003;349:146-153.
Choi, Sarah
core   +3 more sources

LOW MOLECULAR WEIGHT HEPARINS [PDF]

open access: yesMedical Journal Armed Forces India, 1998
Low-molecular-weight heparins (LMWH) are a new group of parenteral anticoagulants. They represent a major clinical advance in anticoagulation since the identification of unfractionated heparin (UFH) in 1922 and the introduction of the synthetic coumarin derivative, warfarin, in 1948.
J N, Huang, A, Shimamura
openaire   +4 more sources

Poly(dimethylsiloxane)-poly(ethyleneoxide)-heparin block copolymers. I. Synthesis and characterization [PDF]

open access: yes, 1988
Amphiphilic block copolymers containing poly(dimethylsiloxane), poly(ethylene oxide), and heparin (PDMS-PEO-Hep) have been prepared via a series of coupling reactions using functionalized prepolymers, diisocyanates, and derivatized heparins.
Agarwal   +40 more
core   +21 more sources

Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture.

open access: yesNew England Journal of Medicine, 2023
BACKGROUND Clinical guidelines recommend low-molecular-weight heparin for thromboprophylaxis in patients with fractures, but trials of its effectiveness as compared with aspirin are lacking.
R. O’Toole   +16 more
semanticscholar   +1 more source

Inhibition of trypsin by heparin and dalteparin, a low molecular weight heparin [PDF]

open access: yesJournal of the Serbian Chemical Society, 2009
The interaction between trypsin, a prototype S1 serine protease, with heparin and its low molecular weight derivative dalteparin were investigated. Direct inhibition of the proteolytic activity of trypsin by heparin and dalteparin, used in concentrations
OLIVERA M. BOSNIĆ   +3 more
doaj   +3 more sources

Low-Molecular Weight Heparin Increases Circulating sFlt-1 Levels and Enhances Urinary Elimination [PDF]

open access: yes, 2014
Rationale: Preeclampsia is a devastating medical complication of pregnancy which leads to maternal and fetal morbidity and mortality. While the etiology of preeclampsia is unclear, human and animal studies suggest that excessive circulating levels of ...
Hagmann, Henning   +10 more
core   +12 more sources

Therapeutic inefficacy of protocol driven intravenous unfractionated heparin infusion in the current era

open access: yesAmerican Heart Journal Plus, 2023
Unfractionated heparin (UFH) is commonly used for several life-threatening conditions requiring anticoagulant therapy but failure to reach therapeutic levels in 24 h can be associated with adverse outcomes.
Kayla Torppey   +7 more
doaj   +1 more source

Low-molecular-weight heparin for prevention of preeclampsia and other placenta-mediated complications: a systematic review and meta-analysis.

open access: yesAmerican Journal of Obstetrics and Gynecology, 2021
BACKGROUND Evidence on the impact of low-molecular-weight heparin, alone or in combination with low-dose aspirin, for the prevention for preeclampsia in high-risk patients is conflicting.
M. Cruz-Lemini   +3 more
semanticscholar   +1 more source

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