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Comparative Analysis of Anticoagulation Stability in Critically Ill Patients Receiving Argatroban for Suspected or Confirmed Heparin-Induced Thrombocytopenia Compared with Unfractionated Heparin: A Retrospective Cohort Study. [PDF]
Khan I +9 more
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Utilizing Argatroban for Neuroendovascular Therapy in Heparin-Induced Thrombocytopenia: A Case Report and Technical Review. [PDF]
Eguchi H +10 more
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Destabilization of PF4-antigenic complexes in heparin-induced thrombocytopenia.
Rauova L +12 more
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Heparin-Induced Thrombocytopenia
Annual Review of Medicine, 2010SummaryHeparin-induced thrombocytopenia (HIT), typically occurring in the second week of heparin therapy, is an antibody-mediated adverse drug reaction associated with increased thrombotic risk. The most important antigens are located on platelet factor 4 (PF4)/heparin complexes.
Gowthami M Arepally
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Heparin-induced thrombocytopenia
Clinical Toxicology, 2014Abstract A summary of heparin-induced thrombocytopenia (HIT) is presented. HIT is an adverse drug reaction characterized by thrombocytopenia and a high risk for venous or arterial thrombosis. The frequency of HIT ranges from 1 to 5% of patients receiving heparin with exact frequencies ranging between specific agents. Interestingly, this immune-mediated
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Heparin-induced thrombocytopenia
Journal of Vascular Nursing, 1995Heparin is one of the most frequently prescribed medications in the United States with more than 1 trillion units being used each year. However, some patients who receive heparin may have development of a rare but severe complication called heparin-induced thrombocytopenia, which is associated with significant morbidity and mortality rates.
D A, Borkowski, R W, Force
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HEPARIN‐INDUCED THROMBOCYTOPENIA
BJU International, 2007Each year, 25% of all hospitalized patients are affected by venous thromboembolism, a disease comprising deep vein thrombosis and pulmonary embolism, that is responsible for up to 10% of all inpatient deaths (Alikhan, Peters, Wilmott, Cohen, 2004). Used in both the treatment and the prevention of venous thromboembolism, heparin is administered to more ...
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Heparin-induced thrombocytopenia
Expert Review of Cardiovascular Therapy, 2004Heparin is widely used for the prevention and treatment of thrombotic and particularly cardiovascular disorders. Unfortunately, 0.5 to 3.0% of patients given heparin develop an immune reaction, commonly termed Type II heparin-induced thrombocytopenia (HIT).
Beng H, Chong, James J H, Chong
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Heparin-Induced Thrombocytopenia
Australian and New Zealand Journal of Medicine, 1988Abstract:Thrombocytopenia is a common adverse effect of heparin therapy. Two types of heparinlinduced thrombocytopenia (HIT) are observed clinically ‐ an early onset mild thrombocytopenia (Type I) in which the patients remain asymptomatic and a delayed onset severe thrombocytopenia (Type II).
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