Results 11 to 20 of about 22,412 (196)

Heparin-Induced Thrombocytopenia [PDF]

New England Journal of Medicine, 1997
Heparin-induced thrombocytopenia (HIT), typically occurring in the second week of heparin therapy, is an antibody-mediated adverse drug reaction associated with increased thrombotic risk. The most important antigens are located on platelet factor 4 (PF4)/heparin complexes.
Naomi B, Klarenbeek, Jeroen C J, Eikenboom   +1 more
openaire   +7 more sources

Heparin-induced thrombocytopenia: a rare presentation with skin necrosis

Dermatology Reports, 2023
Heparin-induced thrombocytopenia is the most clinically relevant non-haemorrhagic complication of heparin and is characterised by the presence of anti-PF4/heparin-IgG antibodies.
Filipa David, Ana Catarina Trigo, José Ribeiro, Joana Cancela   +3 more
doaj   +1 more source

Heparin-Induced Thrombocytopenia in a Patient With Pulmonary Embolism and Bilateral Deep Venous Thrombosis: A Case Report. [PDF]

Cureus
Ojinna BT, Ahmed A, Adeoshun L, Shah ZH.
europepmc   +3 more sources

Heparin-Induced Thrombocytopenia [PDF]

New England Journal of Medicine, 2006
Heparin-induced thrombocytopenia (HIT) is an immune-mediated hypercoagulable disorder caused by antibodies to platelet factor 4 (PF4) and heparin. HIT develops in temporal association with heparin therapy and manifests either as an unexplained thrombocytopenia or thrombocytopenia complicated by thrombosis.
Gowthami M, Arepally, Thomas L, Ortel
  +8 more sources

Heparin-induced thrombocytopenia [PDF]

Hematology, 2013
Abstract Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder caused by antibodies that recognize complexes of platelet factor 4 (PF4) and heparin. HIT is frequently considered in the differential diagnosis of thrombocytopenia occurring in patients on heparin therapy.
Grace M, Lee, Gowthami M, Arepally
openaire   +4 more sources

Understanding heparin-induced thrombosis: A brief review

Medicina Universitaria, 2021
Heparin has been the first line for treatment and prevention of thrombosis for a while. However, one of its non-hemorrhagic effects remains noticeable: heparin-induced thrombocytopenia, mediated by antibodies directed to complexes of platelet factor, and
Mariela Irabien-Zúñiga, Edgar A. Rojas-Guerrero, David Gómez-Almaguer   +2 more
doaj   +1 more source

Platelet factor 4 polyanion immune complexes: heparin induced thrombocytopenia and vaccine-induced immune thrombotic thrombocytopenia

Thrombosis Journal, 2021
Background This is a review article on heparin-induced thrombocytopenia, an adverse effect of heparin therapy, and vaccine-induced immune thrombotic thrombocytopenia, occurring in some patients administered certain coronavirus vaccines.
Payel Datta, Fuming Zhang, Jonathan S. Dordick, Robert J. Linhardt   +3 more
doaj   +1 more source

Rivaroxaban Treatment for Heparin-Induced Thrombocytopenia: A Case Report and a Review of the Current Experience

Case Reports in Hematology, 2020
Heparin-induced thrombocytopenia is a life-threatening complication of exposure to heparin. Heparin-induced thrombocytopenia results from an autoantibody directed against platelet factor 4 in complex with heparin.
Mohamed Aon, Omar Al-Shammari
doaj   +1 more source

Living kidney transplantation without perioperative anticoagulation therapy for a patient with heparin‐induced thrombocytopenia

IJU Case Reports, 2020
Introduction Heparin‐induced thrombocytopenia is an antibody‐mediated acquired prothrombotic state induced by heparin exposure. The risk of thromboembolic diseases in kidney transplantation with heparin‐induced thrombocytopenia without perioperative ...
Hayato Nishida, Hiroki Fukuhara, Atsushi Yamagishi, Noriyuki Hosoya, Osamu Ichiyanagi, Toshihiko Sakurai, Sei Naito, Takuya Yamanobe, Tomoyuki Kato, Norihiko Tsuchiya   +9 more
doaj   +1 more source

Heparin-induced thrombocytopenia and acute colonic pseudo-obstruction after therapeutic anticoagulation in a very elderly patient with hip fracture: a case report

BMC Musculoskeletal Disorders, 2020
Background Hip fractures have become a severe public health problem, especially in very elderly patients. Most of them are treated with low molecular weight heparin as prophylaxis or treatment of venous thromboembolism.
Yijun Liu, Hao Lu, Hailin Xu, Zhongguo Fu, Dianying Zhang, Baoguo Jiang   +5 more
doaj   +1 more source