Results 61 to 70 of about 19,040 (169)

EHA Guidelines on the management of children and adults with hemoglobin SC disease

open access: yesHemaSphere, Volume 10, Issue 10, October 2026.
Abstract HbSC disease is the second most common type of sickle cell disease (SCD) in populations of African origin. Although it is often grouped together with other types of SCD, particularly sickle cell anemia (HbSS), it has unique pathophysiology and a different spectrum of laboratory and clinical features.
David C. Rees   +15 more
wiley   +1 more source

Inhaled Heparin to Shorten Antibiotic Duration in Ventilator‐Associated Pneumonia: A Randomized Double‐Blind Controlled Trial

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Prolonged antibiotic therapy in ventilator‐associated pneumonia (VAP) contributes to antimicrobial resistance. Inhaled heparin has pleiotropic anti‐inflammatory and mucolytic properties. This trial evaluated whether adjunctive nebulized heparin reduces antibiotic duration in VAP using a procalcitonin (PCT)‐guided ...
Anoush Dehnadi Moghadam   +2 more
wiley   +1 more source

Heparin-induced thrombocytopenia

open access: yesBlood Reviews, 1999
Heparin-induced thrombocytopenia with or without thrombosis has been recognized increasingly as a serious complication of heparin use. This article reviews type II heparin-induced thrombocytopenia, which is mediated by an antibody that in most cases has specificity for a complex between heparin and platelet factor 4, a secreted platelet alpha-granule ...
K L, Kaplan, C W, Francis
openaire   +2 more sources

Complete Penile Necrosis in a Patient With Heparin-induced Thrombocytopenia: A Case Report

open access: yesUrology Case Reports, 2014
Penile necrosis is a rare condition that has been mostly described in association with diabetes mellitus and end-stage renal disease. We report an unusual case of acute penile necrosis because of heparin-induced thrombocytopenia.
Anne-Sophie Blais   +2 more
doaj   +1 more source

Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi   +9 more
wiley   +1 more source

Resolution of thrombocytopenia through sodium bicarbonate intervention as an alternative diluent for heparin in an extracorporeal membrane oxygenation patient: a case report

open access: yesJournal of Medical Case Reports
Background Thrombocytopenia is a common and multifaceted complication in patients receiving heparin therapy during extracorporeal membrane oxygenation (ECMO). Its development may result from several mechanisms, such as platelet consumption, hemodilution,
Mashael AlFaifi   +6 more
doaj   +1 more source

Acute Cor Pulmonale Caused by Pulmonary Tumor Thrombotic Microangiopathy as the Initial Presentation of Multiple Myeloma: A Case Report

open access: yesPulmonary Circulation, Volume 16, Issue 4, October 2026.
ABSTRACT Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare cause of acute cor pulmonale, typically associated with advanced solid tumors; its occurrence as the initial presentation of multiple myeloma (MM) has not been described. A 45‐year‐old woman developed acute right heart failure on postoperative day 1 after uterine myomectomy ...
Jianwei Cui, Bingzhen Zhao, Xin Ding
wiley   +1 more source

Post‐Market Analysis of the Xenios Console With the Xlung Tubing Kit 230 for Extracorporeal Membrane Oxygenation After Cardiac Surgery

open access: yesArtificial Organs, Volume 50, Issue 10, Page 1464-1475, October 2026.
This study is a comprehensive post‐market analysis of the Xenios console and XLung kit 230 preconfigured ECMO tubing set in post‐cardiotomy applications. The performance of this device was evaluated and demonstrated in all key clinical areas, with an adequate safety profile.
Luca Conci   +9 more
wiley   +1 more source

Heparin-platelet factor 4 antibodies as a predictor of hypercoagulability in pediatric patients on chronic hemodialysis

open access: yesThe Egyptian Journal of Internal Medicine
Background Heparin, a widely utilized anticoagulant in hemodialysis (HD), is known to sometimes trigger the release of heparin-platelet factor 4 (HPF4) antibodies.
Omar Abdelaziz Mohamed   +3 more
doaj   +1 more source

Acute Intracerebral Hemorrhage Associated with Extensive Venous Thrombosis Due to Spontaneous Heparin-Induced Thrombocytopenia After Total Knee Replacement: A Case Report

open access: yesHematology Reports
Introduction: Heparin-induced thrombocytopenia (HIT) is an autoimmune life-threatening prothrombotic syndrome associated with low platelet count after heparin exposure. Spontaneous heparin-induced thrombocytopenia (S-HIT) is an even less frequent variant
Mehdi Kashani   +2 more
doaj   +1 more source

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