Results 101 to 110 of about 697,556 (384)

hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding. [PDF]

, 2013
This work builds upon our findings that proteins secreted by hESCs exhibit pro-regenerative activity, and determines that hESC-conditioned medium robustly enhances the proliferation of both muscle and neural progenitor cells.
CONBOY, Irina M, Conboy, Michael, Li, Ju, Schaffer, David, Schlesinger, Christina, Vazin, Tandis, Yousef, Hanadie, Zeiderman, Matthew   +7 more
core   +2 more sources

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Heparin-induced thrombocytopenia

Journal of Emergencies, Trauma and Shock, 2011
In the last 7 decades heparin has remained the most commonly used anticoagulant. Its use is increasing, mainly due to the increase in the number of vascular interventions and aging population.
Shaikh Nissar
doaj  

Scatter factor : molecular characteristics and effect on the invasiveness of epithelial cells [PDF]

, 1990
The generation of invasiveness in transformed cells represents an essential step of tumor progression. We have previously shown that MDCK epithelial cells, which are deprived of intracellular adhesion by the addition of anti-Arc-1/uvomorulin antibodies ...
Behrens, Jürgen, Birchmeier, Walter, Vandekerckhove, Joël, Weidner, K Michael   +3 more
core   +2 more sources

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

The 73 S ribosome of Neurospora crassa is the native mitochondrial ribosome [PDF]

, 1977
The effect of the inclusion of EDTA and of heparin, in media used in the isolation of mitochondria, on the mitochindrial previous termribosomenext term has been investigated. 1. 1.
Adelmann, Alberghina, Avadhani, Datema, Grivell, Hallermayer, Kellems, Kroon, Küntzel, Leaver, Leaver, Lizardi, Loening, Monro, Neupert, Neupert, O'Brien, Palmiter, Pene, Schmitt, Taylor, van den Bogert, Vogel, von Rücker, Weiss   +24 more
core   +1 more source

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John, Caitlyn Dang, Nidhi Reddy, Calvin Chao, Karen J. Ho, Bin Jiang   +5 more
wiley   +1 more source

Off-pump coronary artery bypass grafting using continuous heparin infusion

Indian Heart Journal, 2016
Objectives: Levels of anticoagulation during off-pump coronary artery bypass grafting (OPCAB) remain controversial. Prolonged activated clotting time (ACT) during OPCAB increases blood loss during surgery and can also cause paradoxical increase in ...
Kamales Kumar Saha, Dinesh Kumar Sangwan, Pravin K. Shroff, Mandar Manohar Deval, Kakalee K. Saha, Rinu V. Jacob, Ratnaprobha Adsul, Lukash Jagdale   +7 more
doaj   +1 more source

Mast cell clones: a model for the analysis of cellular maturation. [PDF]

, 1982
Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H, Der Simonian, H, Dvorak, AM, Dvorak, HF, Galli, SJ, Goldin, JM, Ishizaka, T, Marcum, JA, Nabel, G, Pyne, K, Rosenberg, RD   +10 more
core   +2 more sources

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source