Results 11 to 20 of about 1,343 (138)

Real‐World Experience with a Human Fibrinogen Concentrate: Clinical Data from Adult and Pediatric Patients Requiring Fibrinogen for Bleeding Control and Prevention

The Journal of Clinical Pharmacology, Volume 63, Issue 11, Page 1186-1196, November 2023., 2023
Abstract Human fibrinogen concentrate (Fibryga) received temporary approval for fibrinogen replacement therapy in France (2017), with subsequent full approval for congenital and acquired hypofibrinogenemia. We evaluated real‐world use for on‐demand treatment of bleeding and prophylaxis to enhance our knowledge on fibrinogen concentrate as an option for
Francois Stéphan, Loriane Gutermann, Stéphanie Bourget, Sarah Djabarouti, Johanna Berdugo, Yann Fardini, Pierre Clerson, Guillaume Hébert, Chafké Belmokhtar   +8 more
wiley   +1 more source

Decompressive surgery in cerebral venous sinus thrombosis due to vaccine‐induced immune thrombotic thrombocytopenia

European Journal of Neurology, Volume 30, Issue 5, Page 1335-1345, May 2023., 2023
Abstract Background and purpose Cerebral venous sinus thrombosis due to vaccine‐induced immune thrombotic thrombocytopenia (CVST‐VITT) is an adverse drug reaction occurring after severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccination.
Katarzyna Krzywicka, Diana Aguiar de Sousa, Charlotte Cordonnier, Felix J. Bode, Thalia S. Field, Dominik Michalski, Johann Pelz, Mona Skjelland, Markus Wiedmann, Julian Zimmermann, Matthias Wittstock, Bruno Zanotti, Alfonso Ciccone, Monica Bandettini di Poggio, Afshin Borhani‐Haghighi, Sophie Chatterton, Avinash Aujayeb, Annemie Devroye, Vanessa Dizonno, Thomas Geeraerts, Fabrizio Giammello, Albrecht Günther, Nasli R. Ichaporia, Timothy Kleinig, Espen S. Kristoffersen, Robin Lemmens, Emmanuel De Maistre, Zahra Mirzaasgari, Jean‐Francois Payen, Jukka Putaala, Marco Petruzzellis, Nicolas Raposo, Elyar Sadeghi‐Hokmabadi, Silvia Schoenenberger, Meenakshisundaram Umaiorubahan, Padmavathy N Sylaja, Anita van de Munckhof, Mayte Sánchez van Kammen, Erik Lindgren, Katarina Jood, Adrian Scutelnic, Mirjam R. Heldner, Sven Poli, Marieke J. H. A. Kruip, Antonio Arauz, Adriana B. Conforto, Sanjith Aaron, Saskia Middeldorp, Turgut Tatlisumak, Marcel Arnold, Jonathan M. Coutinho, José M. Ferro, Cerebral Venous Sinus Thrombosis with Thrombocytopenia Syndrome Study Group   +52 more
wiley   +1 more source

Neurological symptoms and complications in predominantly hospitalized COVID‐19 patients: Results of the European multinational Lean European Open Survey on SARS‐Infected Patients (LEOSS)

European Journal of Neurology, Volume 28, Issue 12, Page 3925-3937, December 2021., 2021
We retrospectively analyzed data from 6537 predominantly hospitalized COVID‐19 patients registered in the European multinational Lean European Open Survey on SARS‐Infected Patients (LEOSS) registry between January 2020 and February 2021. Common neurological symptoms were excessive tiredness (28.0%), headache (18.5%), nausea/emesis (16.6%), muscular ...
Nina N. Kleineberg, Samuel Knauss, Eileen Gülke, Hans O. Pinnschmidt, Carolin E. M. Jakob, Paul Lingor, Kerstin Hellwig, Achim Berthele, Günter Höglinger, Gereon R. Fink, Matthias Endres, Christian Gerloff, Christine Klein, Melanie Stecher, Annika Y. Classen, Siegbert Rieg, Stefan Borgmann, Frank Hanses, Maria M. Rüthrich, Martin Hower, Lukas Tometten, Martina Haselberger, Christiane Piepel, Uta Merle, Sebastian Dolff, Christian Degenhardt, Björn‐Erik O. Jensen, Maria J. G. T. Vehreschild, Johanna Erber, Christiana Franke, Clemens Warnke, the LEOSS Study Group   +31 more
wiley   +1 more source

Umbilical cord mesenchymal stem cells for COVID‐19 acute respiratory distress syndrome: A double‐blind, phase 1/2a, randomized controlled trial

STEM CELLS Translational Medicine, Volume 10, Issue 5, Page 660-673, May 2021., 2021
Abstract Acute respiratory distress syndrome (ARDS) in COVID‐19 is associated with high mortality. Mesenchymal stem cells are known to exert immunomodulatory and anti‐inflammatory effects and could yield beneficial effects in COVID‐19 ARDS. The objective of this study was to determine safety and explore efficacy of umbilical cord mesenchymal stem cell (
Giacomo Lanzoni, Elina Linetsky, Diego Correa, Shari Messinger Cayetano, Roger A. Alvarez, Dimitrios Kouroupis, Ana Alvarez Gil, Raffaella Poggioli, Phillip Ruiz, Antonio C. Marttos, Khemraj Hirani, Crystal A. Bell, Halina Kusack, Lisa Rafkin, David Baidal, Andrew Pastewski, Kunal Gawri, Clarissa Leñero, Alejandro M. A. Mantero, Sarah W. Metalonis, Xiaojing Wang, Luis Roque, Burlett Masters, Norma S. Kenyon, Enrique Ginzburg, Xiumin Xu, Jianming Tan, Arnold I. Caplan, Marilyn K. Glassberg, Rodolfo Alejandro, Camillo Ricordi   +30 more
wiley   +1 more source

Recovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy

Journal of Immunology Research, Volume 2021, Issue 1, 2021., 2021
Liver diseases, including cirrhosis, viral hepatitis, and hepatocellular carcinoma, account for approximately two million annual deaths worldwide. They place a huge burden on the global healthcare systems, compelling researchers to find effective treatment for liver fibrosis‐cirrhosis.
Martín Muñoz-Ortega, Noé Macías-Segura, Javier Ventura-Juárez, Manuel Enrique Ávila-Blanco, Leonardo D. Ponce-Damian, Daniel González-Blas, Esperanza Sánchez-Alemán, Andrés Quintanar-Stephano, Charles Elias Assmann   +8 more
wiley   +1 more source

MODELO EXPERIMENTAL PARA O ESTUDO DA INTERAÇÃO ENTRE METABOLISMO DA GLICOSE E DOS ÁCIDOS GRAXOS LIVRES NO EXERCÍCIO EM CONDIÇÃO DE HIPERLIPEMIA

Revista Brasileira de Atividade Física e Saúde, 2012
Este estudo foi delineado para desenvolver um modelo animal de hiperlipemia crônica, independente de manipulação dietética, vi­sando análise da interação metabólica glicose/ácidos graxos livres (AGL) no exercício.
Maria Alice Rostom de Mello, Cláudio Alexandre Gobatto, Clarice Yoshico Sibuya   +2 more
doaj   +1 more source

Estabilidade do cloridrato de vancomicina empregado em soluções de selo antimicrobiano de cateteres intravenosos centrais [PDF]

Revista Latino-Americana de Enfermagem, 2022
Resumo Objetivo: verificar a estabilidade do cloridrato de vancomicina em soluções de selo antimicrobiano sem e com associação de heparina sódica segundo a temperatura e tempo de associação.
Daniele Porto Barros, Priscilla Sete de Carvalho Onofre, Fernando Luiz Affonso Fonseca, Paulo César Pires Rosa, Mavilde da Luz Gonçalves Pedreira, Maria Angélica Sorgini Peterlini   +5 more
doaj   +1 more source

Investigação da trombose venosa na gravidez Deep vein thrombosis during pregnancy work up

Jornal Vascular Brasileiro, 2008
CONTEXTO: A trombose venosa profunda (TVP) na gravidez é fator determinante no aumento da morbidade e da mortalidade maternofetal. Pode ocorrer na presença de trombofilias, por compressão da veia cava inferior, estase venosa ou alterações hormonais ...
Jorge Agle Kalil, Marco Antonio C. Jovino, Marcelo Arriaga de Lima, Renato Kalil, Maria Elisa Ruffolo Magliari, Marcelo K. Di Santo   +5 more
doaj   +1 more source

The specificity of interactions between proteins and sulfated polysaccharides

Anais da Academia Brasileira de Ciências, 2005
Sulfated polysaccharides are capable of binding with proteins at several levels of specificity. As highly acidic macromolecules, they can bind non-specifically to any basic patch on a protein surface at low ionic strength, and such interactions are not ...
Barbara Mulloy
doaj   +1 more source

Avaliação da técnica de administração subcutânea de heparina na formação de hematomas

Revista Brasileira de Enfermagem, 2002
Este estudo avaliou a presença e extensão de hematomas, dor e complicações após administração subcutânea de heparina de baixa dose, comparando aplicações com a técnica convencional e a técnica modificada, em 60 pacientes internados em um Hospital ...
Aline Aparecida Leite da Silva, Silvia Helena De Bortoli Cassiani, Simone Perufo Optiz   +2 more
doaj   +1 more source