Results 101 to 110 of about 392,626 (135)
Abstract Several commerical batches of heparitin sulfate extracted from beef lung tissue were fractionated into at least four distinct mucopolysaccharides by a combination of polyacrylamide and agarose gel electrophoresis. The four heparitin sulfates (A, B, C and D) were distinguished from each other and from heparin by several physical and chemical ...
Carl P. Dietrich, Helena B. Nader
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The Uronidic Linkages in Heparitin Sulfate
Beta-glucuronidase preparations obtained from various sources were shown to liberate free D-glucuronic acid from heparitin sulfate oligosaccharides. Some free L-iduronic acid could also be detected in the hydrolyzates indicating the presence of an iduronidase in the preparations. The data presented indicate that heparitin sulfate contains a substantial
Alfred Linker
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Effects of preparations of heparin and heparitin sulfate on fibrinolysis
Abstract Some preparations of heparin and heparitin sulfate were found to be contaminated with protease inhibitors. By column chromatography two different inhibitors, both of an acid type, could be demonstrated. Inhibitor-free heparin preparations exerted an enhancing effect on fibrinolysis caused by plasminogen activators.
Tage Astrup+2 more
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Inhibition of atherosclerosis in cholesterol-fed rabbits by a heparitin sulfate
Abstract An apparently non-toxic naturally occurring acid mucopolysaccharide from a mammalian source has been isolated and purified, which has good lipoprotein lipase activating effects, with little anticoagulant activity and is absorbed through the alkaline portion of the bowel.
B.J. Grossman, A.K. Ozoa, J.A. Cifonelli
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Some structural features of heparitin sulfate excreted by patients with Hunter syndrome are described. It is shown, with the aid of heparitinases and heparinase from Flavobacterium heparinum, that the Hunter heparitin sulfate is a very complex structure composed of nine different disaccharide units containing regions akin to normal heparitin sulfate ...
Nader, H. B.+2 more
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AbstractCircular dichroism spectroscopy has been used to study the interactions of hyaluronic acid, heparitin sulfate, and keratan sulfate with cationic polypeptides. The results indicate that the presence of these mucopolysaccharides has an effect in the conformation of poly(L‐lysine) and poly(L‐arginine), such that the former adopts the “random” form
R. A. Gelman, John Blackwell
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The isolation and properties of heparitin sulfate from human umbilical cord tissues
Heparitin sulfate has been isolated from human umbilical cords in a yield of approx. 0.07% of the dry weight of tissue. Heparin was not detected, and if present, it is believed to be in considerably lower concentrations than heparitin sulfate. The isolated heparitin sulfate showed similarity to the material obtained from human aortic tissue in having ...
Judith King, J.A. Cifonelli
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Triolein emboli clearance from the mouse lung: Effect of heparin and heparitin sulfate
Abstract We have designed a model system in mice in which one can study the localization, accumulation, and clearance of experimentally induced pulmonary fat emboli. When 125 I-labeled triolein emulsions are injected via the caudal vein, the lipid is trapped predominantly in the lung vasculature.
Sheldon B. Gertner, Stanley Sherr
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The enzymic degradation of heparitin sulfate
Alfred Linker, Phyllis Sampson
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Structural studies on heparin and heparitin sulfate
J.A. Cifonelli, Albert Dorfman
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