Results 101 to 110 of about 2,301 (124)

Structural studies of heparitin sulfates

Biochimica et Biophysica Acta (BBA) - General Subjects, 1975
Heparitin sulfate fractions with a large range in sulfate content were subjected to degradation by Flavobacterium heparinase and by nitrous acid. The products obtained were fractionated by chromatography, characterized, and used to arrive at tentative structures for these complex polysaccharides.
Peter Hovingh, Alfred Linker
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Effects of preparations of heparin and heparitin sulfate on fibrinolysis

Archives of Biochemistry and Biophysics, 1966
Abstract Some preparations of heparin and heparitin sulfate were found to be contaminated with protease inhibitors. By column chromatography two different inhibitors, both of an acid type, could be demonstrated. Inhibitor-free heparin preparations exerted an enhancing effect on fibrinolysis caused by plasminogen activators.
Tage Astrup, Uwe Nissen, Jørgen Rasmussen   +2 more
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Chemistry of heparitin sulfate and heparin from normal tissues and from patients with hunter syndrome

Biochimica et Biophysica Acta (BBA) - General Subjects, 1979
Some structural features of heparitin sulfate excreted by patients with Hunter syndrome are described. It is shown, with the aid of heparitinases and heparinase from Flavobacterium heparinum, that the Hunter heparitin sulfate is a very complex structure composed of nine different disaccharide units containing regions akin to normal heparitin sulfate ...
Nader, H. B., Cohen, D. M., Dietrich, C. P.   +2 more
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Inhibition of atherosclerosis in cholesterol-fed rabbits by a heparitin sulfate

Atherosclerosis, 1971
Abstract An apparently non-toxic naturally occurring acid mucopolysaccharide from a mammalian source has been isolated and purified, which has good lipoprotein lipase activating effects, with little anticoagulant activity and is absorbed through the alkaline portion of the bowel.
B.J. Grossman, A.K. Ozoa, J.A. Cifonelli
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Fractionation and properties of four heparitin sulfates from beef lung tissueIsolation and partial characterization of a homogeneous species of heparitin sulfate

Biochimica et Biophysica Acta (BBA) - General Subjects, 1974
Abstract Several commerical batches of heparitin sulfate extracted from beef lung tissue were fractionated into at least four distinct mucopolysaccharides by a combination of polyacrylamide and agarose gel electrophoresis. The four heparitin sulfates (A, B, C and D) were distinguished from each other and from heparin by several physical and chemical ...
Carl P. Dietrich, Helena B. Nader
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On the structure of heparitin sulfates Analyses of the products formed from heparitin sulfates by two heparitinases and a heparinase from Flavobacterium heparinum

Biochimica et Biophysica Acta (BBA) - General Subjects, 1976
The analyses of the products formed from heparitin sulfates by the action of two heparitinases and a heparinase from Flavorbacterium heparinum is reported. Heparitin sulfates A and B are degraded by heparitinase I yielding two disaccharides, one of them composed of N-acetylucosamine and an unsaturated uronic, joined by alpha(1 lead to 4) linkage, and ...
Carl P. Dietrich, Maria E. Silva, Helena B. Nader   +2 more
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Isolation and partial characterization of three induced enzymes from flavobacterium heparinum involved in the degradation of heparin and heparitin sulfates

Biochemical and Biophysical Research Communications, 1974
Summary The isolation and partial characterization of two heparitinases and a heparinase from induced extracts from F. heparinum are reported. The heparinase acts upon heparin, heparitin sulfates C and D producing as the main degradation product a trisulfated disaccharide. The heparitinase I degrades only heparitin sulfate A and B producing as main
Carl P. Dietrich, Maria Elena Silva
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The isolation and properties of heparitin sulfate from human umbilical cord tissues

Biochimica et Biophysica Acta (BBA) - General Subjects, 1970
Heparitin sulfate has been isolated from human umbilical cords in a yield of approx. 0.07% of the dry weight of tissue. Heparin was not detected, and if present, it is believed to be in considerably lower concentrations than heparitin sulfate. The isolated heparitin sulfate showed similarity to the material obtained from human aortic tissue in having ...
Judith King, J.A. Cifonelli
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Triolein emboli clearance from the mouse lung: Effect of heparin and heparitin sulfate

Experimental and Molecular Pathology, 1976
Abstract We have designed a model system in mice in which one can study the localization, accumulation, and clearance of experimentally induced pulmonary fat emboli. When 125 I-labeled triolein emulsions are injected via the caudal vein, the lipid is trapped predominantly in the lung vasculature.
Sheldon B. Gertner, Stanley Sherr
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Interactions between mucopolysaccharides and cationic polypeptides in aqueous solution: Hyaluronic acid, heparitin sulfate, and keratan sulfate

Biopolymers, 1974
AbstractCircular dichroism spectroscopy has been used to study the interactions of hyaluronic acid, heparitin sulfate, and keratan sulfate with cationic polypeptides. The results indicate that the presence of these mucopolysaccharides has an effect in the conformation of poly(L‐lysine) and poly(L‐arginine), such that the former adopts the “random” form
R. A. Gelman, John Blackwell
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