Identification of acid mucopolysaccharides by paper chromatography [PDF]
A multiple solvent paper chromatography system is described which tentatively identifies most of the known mammalian acid mucopolysaccharides, when these are examined singly.
Dorstewitz, Emily L., William Castor, C.
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The identification of proteoglycans and glycosaminoglycans in archaeological human bones and teeth [PDF]
Bone tissue is mineralized dense connective tissue consisting mainly of a mineral component (hydroxyapatite) and an organic matrix comprised of collagens, non-collagenous proteins and proteoglycans (PGs).
A Hildebrand+70 more
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Sanfilippo syndrome or mucopolysaccharidosis III is an automosal recessive genetic disease, where there is an alteration in the enzymes responsible for the metabolism of long sugar chains, called glucominoglycans (mucopolysaccharides).
Rappaccioli Salinas, Renata
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Shear Stress Induces the Release of an Endothelial Elastase: Role in Integrin alpha(v)beta(3)-Mediated FGF-2 Release [PDF]
Background/Aims: Laminar shear stress is an important stimulus in the endothelium-dependent control of vascular tone and of vascular remodeling processes.
Gloe, Torsten+4 more
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The anionic sites at luminal surface of peritubular capillaries in rats [PDF]
The anionic sites at luminal surface of peritubular capillaries in rats. Anionic sites have been demonstrated in the basement membranes of peritubular capillaries.
Avasthi, Pratap S., Koshy, Valsala
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Cathepsin B-associated Activation of Amyloidogenic Pathway in Murine Mucopolysaccharidosis Type I Brain Cortex [PDF]
Mucopolysaccharidosis type I (MPS I) is caused by genetic deficiency of alpha-l-iduronidase and impairment of lysosomal catabolism of heparan sulfate and dermatan sulfate.
Baldo, G+9 more
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Glycosaminoglycan Synthesis by Human Keratinocytes: Cell Growth and Medium Calcium Effects [PDF]
The influences of cell density, differentiation, and medium calcium levels on glycosaminoglycan biosynthesis were evaluated in cultured human epidermal keratinocytes. Following metabolic labeling with [35S]-sulfate and [3H]-glucosamine under steady state
Carney, Helen+3 more
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Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application [PDF]
Heparin is a promising antimalarial drug due to its activity in inhibiting Plasmodium invasion of red blood cells and to the lack of resistance evolution by the parasite against it, but its potent anticoagulant activity is preventing the advance of ...
Aláez Versón, Carlos Raúl+4 more
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Sanfilippo syndrome: molecular basis, disease models and therapeutic approaches [PDF]
Sanfilippo syndrome or mucopolysaccharidosis III is a lysosomal storage disorder caused by mutations in genes responsible for the degradation of heparan sulfate, a glycosaminoglycan located in the extracellular membrane.
Benetó, Noelia+3 more
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Proteolysis, NaOH and ultrasound-enhanced extraction of anticoagulant and antioxidant sulfated polysaccharides from the edible seaweed, Gracilaria birdiae [PDF]
The sulfated polysaccharides (SP) from the edible red seaweed, Gracilaria birdiae, were obtained using five different extraction conditions: Gracilaria birdiae 1 (GB1)-water; GB1s-water/sonication; GB1sp-water/sonication/proteolysis; GB2s-NaOH/sonication;
Costa, Leandro Silva+6 more
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