Structural Studies on Heparitin Sulfate of Normal and Hurler Tissues
Abstract Heparitin sulfate isolated from human aorta is a polysaccharide of molecular weight 24,000 to 29,000, which is bound to protein by way of serine. The presence of serine, xylose, and galactose in a molar ratio of 1:1:2 suggests that the linkage region of this mucopolysaccharide is similar to that in chondroitin 4-sulfate and in heparin ...
Judith Knecht +2 more
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Effect of Heparitin Sulfate Fractions on Coagulation and Hemostasis [PDF]
SummaryThe antihemostatic and anticoagulant activities of heparin and heparitin sulfate fractions were compared. Heparitin sulfate D has the same antihemostatic activity as heparin but negligible anticoagulant activity, demonstrating differences in the molecular mechanisms of these two biological processes.
Helena B. Nader, Carl P. Dietrich
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The Enzymatic Degradation of Heparin and Heparitin Sulfate
Peter Hovingh, Alfred Linker
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Heparitin Sulfate Mucopolysaccharidosis (Sanfilippo Disease): A Case Study with Ultrastructural, Biochemical, and Radiological Findings [PDF]
Extract: A case study of a 14-year-old female child who developed normally for 18 months but subsequently deteriorated rapidly in mental status and social behavior is reported. Histochemical studies of tissues removed at biopsy from liver, skin, and bone marrow showed changes similar to those found in the Hurler syndrome. Ultrastructural changes of the
M. Daria Haust +4 more
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Proteolysis, NaOH and ultrasound-enhanced extraction of anticoagulant and antioxidant sulfated polysaccharides from the edible seaweed, Gracilaria birdiae [PDF]
The sulfated polysaccharides (SP) from the edible red seaweed, Gracilaria birdiae, were obtained using five different extraction conditions: Gracilaria birdiae 1 (GB1)-water; GB1s-water/sonication; GB1sp-water/sonication/proteolysis; GB2s-NaOH/sonication;
Costa, Leandro Silva +6 more
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Chondroitin Sulfate Proteoglycans Are Associated with the Lesions of Alzheimer\u27s Disease [PDF]
Chondroitin sulfate proteoglycans (CSPG) are extracellular matrix proteins inhibitory to neurite outgrowth in vitro and correlated with decreased neurite outgrowth after CNS injury.
Canning, David R. +3 more
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Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin [PDF]
Cell surface heparan sulfate (HS) proteoglycans are carbohydrate-rich regulators of cell migratory, mitogenic, secretory, and inflammatory activity that bind and present soluble heparin-binding growth factors (e.g., fibroblast growth factor, Wnt, Hh ...
Beck, Shannon L. +8 more
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Role of heparan sulfate as a tissue-specific regulator of FGF-4 and FGF receptor recognition [PDF]
FGF signaling uses receptor tyrosine kinases that form high-affinity complexes with FGFs and heparan sulfate (HS) proteoglycans at the cell surface.
Allen, Benjamin L. +2 more
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Chondroitin sulphate mediated fusion of brain: neural folds in rat embryons [PDF]
Producción CientíficaPrevious studies have demonstrated that during neural fold fusion in different species, an apical extracellular material rich in glycoconjugates is involved.
Alonso Revuelta, María Isabel +8 more
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小児における尿中酸性ムコ多糖類の排泄パターンに関する研究 第1編 正常小児の尿中酸性ムコ多糖類の排泄パターン [PDF]
Qualitative and quantitative determination of urinary acid mucopolysaccharide (AMPS) have been studied by several methods including ECTEOLA cellulose column chromatography, Dowex I-X 2 column chromatography, electrophoresis, and enzymatic digestion with
南 良二
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