Results 151 to 160 of about 56,941 (257)

Comparative Diagnostic Sensitivity of Endoscopic Ultrasound‐guided Tissue Acquisition for Hepatocellular Carcinoma Versus Intrahepatic Cholangiocarcinoma

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aims Accurate histological differentiation between hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is essential for selecting appropriate treatment. Endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) is increasingly used for focal liver lesions; however, comparative data on its diagnostic ...
Yuichi Takano   +11 more
wiley   +1 more source

Translational Gap in Biomarker Discovery: Tumor Surface Markers Rarely Mirror Circulating Levels

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1594-1601, September 2026.
ABSTRACT Background Tumor‐associated cell surface proteins are frequently proposed as circulating biomarkers for colorectal cancer (CRC) based on their high tumor expression. However, many candidates identified through tissue‐based analyses fail to translate into clinically useful biomarkers.
Junko Mukohyama   +9 more
wiley   +1 more source

Prognostic Impact of Arterial Phase Hyperenhancement After Proton Beam Therapy for Untreated Solitary Hepatocellular Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Purpose To evaluate the significance of persistent arterial‐phase hyperenhancement (APHE) on contrast‐enhanced CT/MRI at 6 and 12 months after proton beam therapy (PBT) for hepatocellular carcinoma (HCC). Methods We retrospectively analyzed 108 patients with solitary HCC without vascular invasion who underwent definitive PBT as initial ...
Hikaru Niitsu   +16 more
wiley   +1 more source

Synchronous Vaginal and Liver Metastases in Rectosigmoid Cancer: Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Vaginal metastasis from colorectal cancer is extremely rare. We report the case of a 58‐year‐old postmenopausal woman with rectosigmoid adenocarcinoma and synchronous liver and vaginal metastases who initially presented with gastrointestinal symptoms followed by vaginal bleeding.
Tamader Alyaarabi   +7 more
wiley   +1 more source

Liver Transplantation Despite Active Intracranial Hemorrhage in Acetaminophen‐Induced Acute Liver Failure: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Acute liver failure with intracranial hemorrhage poses difficult transplant decisions. We report acetaminophen‐induced acute liver failure with cerebral edema and active multifocal hemorrhage successfully managed with emergent liver transplantation and staged neurosurgical intervention.
Daryna Shnitser   +3 more
wiley   +1 more source

Beyond the Black Box: Is Artificial Intelligence Ready to Reshape Neurosurgical Decision‐Making? A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Artificial intelligence (AI) is increasingly being integrated into neurosurgical practice, offering capabilities in diagnostic imaging, surgical planning, and outcome prediction. However, the “black box” nature of many AI systems generating recommendations without a transparent rationale poses fundamental challenges to ...
Dip Bahadur Singh   +2 more
wiley   +1 more source

Guanosine Attenuates Astrocyte-Associated Glutamatergic Dysregulation and Improves Survival in Acute Liver Failure-Induced Hepatic Encephalopathy. [PDF]

open access: yesMetabolites
Guazzelli PA   +8 more
europepmc   +1 more source

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