Results 21 to 30 of about 58,160 (267)

Outcomes of surgery for giant hepatic hemangioma

BMC Surgery, 2021
Background The surgical indications for liver hemangioma remain unclear. Methods Data from 152 patients with hepatic hemangioma who underwent hepatectomy between 2004 and 2019 were retrospectively reviewed.
Qing-song Xie, Zi-xiang Chen, Yi-jun Zhao, Heng Gu, Xiao-ping Geng, Fu-bao Liu   +5 more
doaj   +1 more source

Efficacy of Tislelizumab plus Lenvatinib in hepatocellular carcinoma after curative hepatectomy: a real-world study. [PDF]

Front Immunol
BackgroundThe efficacy of adjuvant therapy after curative resection for hepatocellular carcinoma (HCC) patients is still debated. This study aimed to evaluate the impact of adjuvant Tislelizumab combined with Lenvatinib on the prognosis of patients with ...
Chen K, Feng X, Shi Y, Xiao H, Lan X, Shi ZR.   +5 more
europepmc   +2 more sources

Appropriate indications for laparoscopic repeat hepatectomy

BMC Surgery, 2023
Background Laparoscopic repeat hepatectomy (LRH) has increased, but appropriate indications for LRH are unclear. This study aimed to clarify appropriate indications for LRH. Methods We retrospectively compared surgical outcomes between open RH (ORH) (n = 
Takashi Masuda, Yuichi Endo, Shota Amano, Masahiro Kawamura, Atsuro Fujinaga, Takahide Kawasaki, Yoko Kawano, Teijiro Hirashita, Masayuki Ohta, Masafumi Inomata   +9 more
doaj   +1 more source

Transarterial Chemoembolization Combined With Radiofrequency Ablation Versus Repeat Hepatectomy for Recurrent Hepatocellular Carcinoma After Curative Resection: A 10-Year Single-Center Comparative Study

Frontiers in Oncology, 2021
BackgroundThe purpose of this study was to compare the efficacy and safety of transarterial chemoembolization (TACE) in combination with radiofrequency ablation (RFA) (TACE-RFA) and repeat hepatectomy in the treatment of recurrent hepatocellular ...
Xin Zheng, Yanqiao Ren, Yanqiao Ren, Hanqing Hu, Kun Qian, Kun Qian   +5 more
doaj   +1 more source

Study on anxiety and depression in elderly patients with malignant liver tumor undergoing hepatectomy

European Journal of Medical Research, 2023
Background Patients with malignant tumors are more likely to have psychological problems due to their worries about their life expectancy. To understand the psychological status of elderly patients with malignant liver tumor undergoing hepatectomy better,
Lining Xu, Yingying Xu, Guiping Li, Bo Yang   +3 more
doaj   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Hepatectomies [PDF]

, 2009
Hepatectomies in the rat can be improved using microsurgical techniques. The distribution variations of the vascular and biliar lobular branches of the liver are observed under magnification with an operating microscope and, therefore their dissection, ligation and section are more accurate. The vascularization and bile drainage of the caudate process,
Maria-Angeles Aller, Laureano Lorente, Isabel Prieto, Jaime Arias   +3 more
openaire   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Risk factors of postoperative bile leakage after liver resection: A systematic review and meta‐analysis

Cancer Medicine, 2023
Objective Postoperative bile leakage (POBL) is one of the most common complications after liver resection. However, current studies on the risk factors for POBL and their impacts on surgical outcomes need to be more consistent. This study aims to conduct
Shuai Xue, Haichuan Wang, Xiangzheng Chen, Yong Zeng   +3 more
doaj   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source