Results 161 to 170 of about 678,448 (346)

Non-absorbable disaccharides versus placebo/no intervention and lactulose versus lactitol for the prevention and treatment of hepatic encephalopathy in people with cirrhosis [PDF]

open access: yes, 2016
Background Non-absorbable disaccharides (lactulose and lactitol) are recommended as first-line treatment for hepatic encephalopathy. The previous (second) version of this review included 10 randomised clinical trials (RCTs) evaluating non-absorbable ...
Agrawal   +137 more
core   +2 more sources

Pharmacotherapy for Cirrhosis in Japan

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
As cirrhosis progresses from the compensated to the decompensated stage, liver disease‐related events such as varices, ascites, encephalopathy, sarcopenia, jaundice, and bleeding tendency, as well as liver carcinogenesis, can occur at a high rate. With the advent of new pharmacotherapies for cirrhosis in the last decade, liver fibrosis has been shown ...
Hiroki Nishikawa, Soo Ki Kim, Akira Asai
wiley   +1 more source

Differential metabolic and cellular brain regional susceptibility in adult rats with chronic liver disease [PDF]

open access: yesarXiv
Background & Aims: Patients with type C hepatic encephalopathy (HE) present diverse symptoms indicating that various brain regions are affected. Understanding the distinct metabolic and cellular changes across these regions could help explain the clinical variability of HE.
arxiv  

Assessment of intestinal inflammation via fecal calprotectin for early prediction of adverse outcomes in advanced chronic liver disease

open access: yesUnited European Gastroenterology Journal, Volume 13, Issue 3, Page 305-316, April 2025.
Abstract Background and aims Intestinal inflammation assessed by fecal calprotectin (F‐CAL) in advanced chronic liver disease (ACLD) may represent an early sign of intestinal barrier dysfunction. We aimed to explore the usefulness of F‐CAL testing in ACLD in the prediction of adverse outcomes (AO, death, or LT) and refinement of prognostic ...
Tomas Koller   +6 more
wiley   +1 more source

Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]

open access: yes, 2010
This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique   +7 more
core   +1 more source

A Markov model for the spread of Hepatitis C [PDF]

open access: yesarXiv, 2008
We propose a Markov model for the spread of Hepatitis C virus (HCV) among drug users who use injections. We then proceed to an asymptotic analysis (large initial population) and show that the Markov process is close to the solution of a non linear autonomous differential system.
arxiv  

The utility of scoring systems in critically ill cirrhotic patients admitted to a general intensive care unit [PDF]

open access: yes, 2014
Purpose: This study aimed to establish which prognostic scoring tool provides the greatest discriminative ability when assessing critically ill cirrhotic patients in a general intensive care unit (ICU) setting.<p></p> Methods: This was a 12-
Emerson, Philip   +7 more
core   +1 more source

BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): II. 2-year Neurocognitive Outcome and NICU Outcome [PDF]

open access: yesarXiv
Hypoxic Ischemic Encephalopathy (HIE) affects approximately 1-5/1000 newborns globally and leads to adverse neurocognitive outcomes in 30% to 50% of cases by two years of age. Despite therapeutic advances with Therapeutic Hypothermia (TH), prognosis remains challenging, highlighting the need for improved biomarkers.
arxiv  

Modeling the dynamics of Hepatitis C Virus with combined antiviral drug therapy: Interferon and Ribavirin [PDF]

open access: yesarXiv, 2011
A mathematical modeling of Hepatitis C Virus (HCV) dynamics has been presented in this paper. The proposed model, which involves four coupled ordinary differential equations, describes the interaction of target cells (hepatocytes), infected cells, infectious virions and non-infectious virions.
arxiv  

Multiple Concomitant Precipitating Factors of Hepatic Encephalopathy Are Associated With a Poor Prognosis in Patients With Cirrhosis Admitted to Intensive Care Unit

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Management of hepatic encephalopathy relies on the identification and control of precipitating factors (PF). The prognostic value of a PF is unknown, which we aimed to explore. Patients and Methods Single‐center retrospective study of cirrhotic patients included in a prospective cohort admitted to an intensive care unit (ICU ...
Marika Rudler   +7 more
wiley   +1 more source

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