Results 161 to 170 of about 694,423 (327)
Our study demonstrates that total BCAA levels increase following liver transplantation. In patients with cirrhosis, higher total BCAA levels are associated with a reduced risk of all‐cause mortality. However, while this association is not observed in liver transplant recipients, elevated total BCAA levels are strongly linked to an increased risk of new‐
Yakun Li+9 more
wiley +1 more source
Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats [PDF]
Birgit A. P. M. Vogels+4 more
openalex +1 more source
Cortical hemodynamics of electrographic status epilepticus in the critically ill
Abstract Objectives The pathophysiological mechanisms of status epilepticus (SE) underlying potential brain injury remain largely unclear. This study aims to employ functional near‐infrared spectroscopy (fNIRS) combined with video‐electroencephalography (vEEG) to monitor brain hemodynamics continuously and non‐invasively in critically ill adult ...
Ali Kassab+6 more
wiley +1 more source
Somatosensory evoked potentials in hepatic encephalopathy
Vittorio Crespi, Luigi Roffi
openalex +1 more source
Hepatic plasma flow estimated according to fick’s principle in patients with hepatic encephalopathy: Evaluation of indocyanine green and d-sorbitol as test substances [PDF]
Jens Otto Clemmesen+2 more
openalex +1 more source
Abstract Objective Current weight‐based dosing fails to account for pharmacokinetic variability in refractory and superrefractory status epilepticus (RSE, SRSE). However, understanding pharmacokinetics in critically ill patients with varying degrees of organ dysfunction can improve both safety and efficacy.
Maximilian Stoschus+9 more
wiley +1 more source
Topiramate for the treatment of neonatal seizures and beyond
Abstract Acute symptomatic neonatal seizures are one of the most common neurological disorders in newborns admitted to neonatal intensive care units and require prompt treatment. Up to 50% of neonatal seizures are refractory to first‐line medications such as phenobarbital (PB), and another 30% fail second‐line therapy.
Wolfgang Löscher, Janet S. Soul
wiley +1 more source
Novel neuropathological observations in an adult with Dravet syndrome
Abstract Dravet syndrome (DS) is a developmental and epileptic encephalopathy associated with pathogenic variants in the SCN1A gene. The neuropathological features of adult DS remain poorly understood. We report the postmortem findings of a 55‐year‐old woman with DS due to a confirmed SCN1A pathogenic variant leading to Nav1.1 loss of function ...
Danielle M. Andrade+7 more
wiley +1 more source