Results 11 to 20 of about 92,598 (348)
The Saudi Journal of Gastroenterology, 2012 Chronic liver disease and cirrhosis affect hundreds of millions of patients all over the world. The majority of patients with cirrhosis will eventually develop complications related to portal hypertension.
Wissam Bleibel, Abdullah M. S. Al-Osaimi
doaj +7 more sources
Pathogenesis of Hepatic Encephalopathy [PDF]
Gastroenterology Research and Practice, 2012 Hepatic encephalopathy can be a serious complication of acute liver failure and chronic liver diseases, predominantly liver cirrhosis. Hyperammonemia plays the most important role in the pathogenesis of hepatic encephalopathy.
Irena Ciećko-Michalska +3 more
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DMW - Deutsche Medizinische Wochenschrift, 2001 Hepatic encephalopathy (HE) is a reversible syndrome of impaired brain function occurring in patients with advanced liver diseases. The precise pathophysiology of HE is still under discussion; the leading hypothesis focus on the role of neurotoxins, impaired neurotransmission due to metabolic changes in liver failure, changes in brain energy metabolism,
J P, Ong, K D, Mullen
+13 more sources
Neurology, 1993 The approach to the management of patients with HE is summarized in Table 3. Other diagnoses need to be excluded and, after a diagnosis of HE is made on clinical and possibly electroencephalographic grounds, a search made for precipitants. Sedatives and opiates should be avoided, and steps taken to avoid hypoglycaemia, fluid overload or electrolyte ...
Harold O. Conn
+5 more sources
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2017 This article reviews hepatic encephalopathy (HE) in companion animals. Clinical signs and categories of hepatic disease likely to cause HE are discussed. Ammonia has a key role in pathogenesis and current concepts in body ammonia metabolism are reviewed. Inflammation and manganese accumulation are also thought to be important in pathogenesis. Treatment
openaire +6 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Case Reports in Hepatology, 2023 Hepatic encephalopathy (HE) is a frequent and serious complication of chronic liver disease. The mechanism of hepatic encephalopathy is not entirely clear. Hepatic encephalopathy is defined as brain dysfunction caused by liver insufficiency and/or portal-
Fady Salama +3 more
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Ammonia toxicity: from head to toe? [PDF]
, 2016 Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan +6 more
core +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran +17 more
wiley +1 more source
Трансплантология (Москва), 2021 The aim was to study the results of using various treatment regimens for hepatic encephalopathy for patients with liver cirrhosis before and after liver transplantation and the effect on the incidence and severity of hepatic encephalopathy in the ...
S. E. Voskanyan +12 more
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