Results 11 to 20 of about 669,583 (341)
The Saudi Journal of Gastroenterology, 2012 Chronic liver disease and cirrhosis affect hundreds of millions of patients all over the world. The majority of patients with cirrhosis will eventually develop complications related to portal hypertension.
Wissam Bleibel, Abdullah M. S. Al-Osaimi
doaj +9 more sources
Hepatic encephalopathy: A review
Annals of Hepatology, 2003 Hepatic encephalopathy (HE) is a complication that presents in as many as 28% of patients with cirrhosis, and reported up to ten years after the diagnosis of cirrhosis. Commonly, it is observed in patients with severe hepatic failure and is characterized
Javier Lizardi-Cervera, MD +3 more
doaj +4 more sources
Pathogenesis of Hepatic Encephalopathy [PDF]
Gastroenterology Research and Practice, 2012 Hepatic encephalopathy can be a serious complication of acute liver failure and chronic liver diseases, predominantly liver cirrhosis. Hyperammonemia plays the most important role in the pathogenesis of hepatic encephalopathy.
Irena Ciećko-Michalska +3 more
doaj +4 more sources
DMW - Deutsche Medizinische Wochenschrift, 2001 Hepatic encephalopathy (HE) is a reversible syndrome of impaired brain function occurring in patients with advanced liver diseases. The precise pathophysiology of HE is still under discussion; the leading hypothesis focus on the role of neurotoxins, impaired neurotransmission due to metabolic changes in liver failure, changes in brain energy metabolism,
Srinivasan Dasarathy, Kevin D. Mullen
+15 more sources
Neurology, 1993 The approach to the management of patients with HE is summarized in Table 3. Other diagnoses need to be excluded and, after a diagnosis of HE is made on clinical and possibly electroencephalographic grounds, a search made for precipitants. Sedatives and opiates should be avoided, and steps taken to avoid hypoglycaemia, fluid overload or electrolyte ...
Harold O. Conn
+7 more sources
Management of hepatic encephalopathy. [PDF]
Journal of Gastroenterology and Hepatology, 1981 Abstract Hepatic encephalopathy (HE) is seen as a clinical manifestation of low grade chronic cerebral edema, which is accompanied by alterations in glioneural communication. Different factors such as ammonia, inflammatory cytokines, benzodiazepines and electrolyte imbalances may precipitate or aggravate glia edema, thereby explaining precipitation of
Dieter Häussinger, Gerald Kircheis
openalex +5 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran +17 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2022 Objective: To determine the association of serum Ammonia levels with severity of grades of hepatic encephalopathy in patients presenting to the department. Study Design: Comparative cross-sectional study.
Muhammad Dawood +5 more
doaj +1 more source
Veterinary Clinics of North America: Small Animal Practice, 2017 This article reviews hepatic encephalopathy (HE) in companion animals. Clinical signs and categories of hepatic disease likely to cause HE are discussed. Ammonia has a key role in pathogenesis and current concepts in body ammonia metabolism are reviewed. Inflammation and manganese accumulation are also thought to be important in pathogenesis. Treatment
openaire +6 more sources