Results 201 to 210 of about 678,448 (346)
The role of blinatumomab in adult acute B lymphoblastic leukaemia
British Journal of Haematology, EarlyView.Blinatumomab, a CD19‐directed bispecific T‐cell engager, has become a crucial part of BCP‐ALL therapy in r/r disease, MRD‐positive disease and has recently been implemented into first‐line therapy of BCP‐ALL. This review discusses important clinical trials with a focus on blinatumomab in first‐line therapy of adult BCP‐ALL.
Anne C. Wilke, Nicola Gökbuget
wiley +1 more source
The burden of hepatic encephalopathy in Latin America
Annals of Hepatology, 2011 Hepatic encephalopathy (HE) is a neuropsychiatric syndrome characterized by changes in cognitive function, behavior, and personality, as well as by transient neurological symptoms and electroencephalographic changes, which occur in the context of acute ...
Milagros Dávalos Moscol +1 more
doaj
Clinical Endocrinology, EarlyView.ABSTRACT Objective Managing gastrointestinal symptoms in patients with phaeochromocytoma and paraganglioma (PPGL) is challenging due to the risk of catecholaminergic crisis with many commonly prescribed medications, especially in functional tumours.
Monica Majumder +5 more
wiley +1 more source
Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging
Cell Proliferation, EarlyView.Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi +6 more
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European Journal of Clinical Investigation, Volume 55, Issue 6, June 2025.This systematic review and meta‐analysis evaluated the impact of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) on hepatocellular carcinoma (HCC) and liver decompensation in patients with type 2 diabetes. Analysing over 641,377 patients, GLP‐1RA use was associated with a significant 58% reduction in HCC risk, particularly in patients with ...
Andrea Pasta +4 more
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The Relationship of Plasma Zinc Concentration and Hepatic Encephalopathy in Patients with Cirrhosis
مجله دانشکده پزشکی اصفهان, 2014 Background: Zinc deficiency is prevalent in Iran. Regarding the effect of zinc element on pathogenesis of cirrhosis and hepatic encephalopathy, the present study has been designed to assess the zinc deficiency in patients with cirrhosis, with and without
Rahmatollah Rafiei +4 more
doaj
The impact of immature granulocytes on the outcome of patients with decompensated cirrhosis
European Journal of Clinical Investigation, EarlyView.Immature granulocyte (IG) count and percentage had a predictive role in patients with decompensated cirrhosis, making them an objective and easily available marker of prognosis for this group of patients. In addition, IG percentage was the only factor independently associated with transplant‐free survival.
Magdalini Adamantou +10 more
wiley +1 more source
Cortical hemodynamics of electrographic status epilepticus in the critically ill
Epilepsia, Volume 66, Issue 3, Page 802-816, March 2025.Abstract Objectives The pathophysiological mechanisms of status epilepticus (SE) underlying potential brain injury remain largely unclear. This study aims to employ functional near‐infrared spectroscopy (fNIRS) combined with video‐electroencephalography (vEEG) to monitor brain hemodynamics continuously and non‐invasively in critically ill adult ...
Ali Kassab +6 more
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Hepatology Research, Volume 55, Issue 4, Page 556-566, April 2025.A nationwide registry named REAL has been developed to collect data on the initial diagnosis, each admission for recurrent disease, and prognosis of primary liver cancer and decompensated liver cirrhosis in Japan. The current study revealed that the prognosis of patients with liver cancer was similar among different etiologies. Abstract Aim Tumor stage
Kazuya Okushin +17 more
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