Hepatocellular Carcinoma and Associated Clinical Features in Latino and Caucasian Patients from a Single Center. [PDF]
INTRODUCTION AND AIM:Hepatocellular carcinoma (HCC) is the most common type of liver cancer in adults and has seen a rapid increase in incidence in the United States. Racial and ethnic differences in HCC incidence have been observed, with Latinos showing
Kieffer, Dorothy A+3 more
core +1 more source
Hepatic encephalopathy (HE) is a devastating complication of cirrhosis. Data are limited regarding the incidence of and risk factors for HE among contemporary patients in the context of the shifting epidemiology of cirrhosis.
E. Tapper+4 more
semanticscholar +1 more source
Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure [PDF]
Background: The development of effective therapies for acute liver failure (ALF) is limited by our knowledge of the pathophysiology of this condition, and the lack of suitable large animal models of acetaminophen toxicity.
A Francavilla+37 more
core +4 more sources
Hepatic Encephalopathy in Cirrhosis: Pathology and Pathophysiology
Neuropathology of hepatic encephalopathy (HE) in cirrhosis is primarily astroglial in nature characterized by Alzheimer type 2 astrocytosis together with activation of microglia indicative of neuroinflammation. Focal loss of neurons may also occur in the
R. Butterworth
semanticscholar +1 more source
The risk of bleeding and encephalopathy in surgical patients with liver cirrhosis [PDF]
Liver cirrhosis is a disease with an increasing incidence. Surgical procedures in patients with cirrhosis are also increasing, due to a longer life expectancy in these patients and also to the improvement of therapeutic and diagnostic resources ...
Bacalbașa, Nicolae+9 more
core +1 more source
Symptom Domain Groups of the Patient-Reported Outcomes Measurement Information System Tools Independently Predict Hospitalizations and Re-hospitalizations in Cirrhosis [PDF]
Background Patient-Reported Outcomes Measurement Information System (PROMIS) tools can identify health-related quality of life (HRQOL) domains that could differentially affect disease progression.
Bajaj, Jasmohan S.+14 more
core +2 more sources
Hepatic Encephalopathy: A Review
Hepatic encephalopathy (HE) is a reversible syndrome observed in patients with liver disease. The syndrome is characterised by a spectrum of neuropsychiatric abnormalities resulting from the accumulation of neurotoxic substances in the bloodstream and ...
Savan Kabaria+6 more
doaj +1 more source
Mathematical model of immune response to hepatitis B [PDF]
A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady states is performed to identify parameter regions where the model exhibits clearance of infection, maintenance of a ...
arxiv +1 more source
Sarcopenia from mechanism to diagnosis and treatment in liver disease [PDF]
Sarcopenia or loss of skeletal muscle mass is the major component of malnutrition and is a frequent complication in cirrhosis that adversely affects clinical outcomes.
Dasarathy, Srinivasan, MERLI, Manuela
core +1 more source
Diagnosis and treatment of hepatic encephalopathy
Background. Hepatic encephalopathy (HE) is a neuropsychiatric complication of liver cirrhosis which symptoms may vary from imperceptible to severe ones. In recent years, there have been some changes of fundamental hepatic encephalopathy pathogenesis and ...
Ilona Savlan+2 more
doaj +1 more source