Results 11 to 20 of about 1,196,134 (401)
Pathophysiology and Treatment Options for Hepatic Fibrosis: Can It Be Completely Cured?
Cells, 2021 Hepatic fibrosis is a dynamic process that occurs as a wound healing response against liver injury. During fibrosis, crosstalk between parenchymal and non-parenchymal cells, activation of different immune cells and signaling pathways, as well as a ...
A. Khanam, P. Saleeb, S. Kottilil
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Pathogenesis of Viral Hepatitis-Induced Chronic Liver Disease: Role of Extracellular Vesicles
Frontiers in Cellular and Infection Microbiology, 2020 Extracellular vesicles are encapsulated lipid nanoparticles secreted by a variety of cell types in living organisms. They are known to carry proteins, metabolites, nucleic acids, and lipids as their cargoes and are important mediators of intercellular ...
Hong Kiat Lim +6 more
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Frontiers in Cell and Developmental Biology, 2021 Hepatic fibrosis is the final pathway of several chronic liver diseases, which is characterized by the accumulation of extracellular matrix due to chronic hepatocyte damage. Activation of hepatic stellate cells and oxidative stress (OS) play an important
Wenzhang Dai +17 more
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Hepatology, 2021 Hepatic fibrosis secondary to HCV infection can lead to cirrhosis and hepatic decompensation. Sustained virologic response (SVR) is possible with direct‐acting antiviral drug regimens; however, patients with advanced fibrosis have an increased risk for ...
E. Lawitz +11 more
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Scientific Reports, 2021 Aspartate aminotransferase-to-platelet ratio index (APRI) and Fibrosis-4 Index (Fib4) have been validated against liver biopsy for detecting advanced hepatic fibrosis in HFE hemochromatosis.
Sim Yee Ong +13 more
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Pharmacological Research, 2023 Hepatic fibrosis is caused by liver damage as a consequence of wound healing response. Recent studies have shown that hepatic fibrosis could be effectively reversed, partly through regression of activated hepatic stellate cells (HSCs).
Liangyun Li +10 more
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Advances on Nanomedicines for Diagnosis and Theranostics of Hepatic Fibrosis
Advanced NanoBiomed Research, 2021 Hepatic fibrosis is induced by chronic hepatic injuries before it turns into hepatic cirrhosis/carcinoma. It is characterized by the formation of collagen and other extracellular matrices around damaged hepatic tissues; consequently, the normal ...
Xinghang Dai +5 more
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Adipocytokines and hepatic fibrosis [PDF]
Trends in Endocrinology & Metabolism, 2015 Obesity and metabolic syndrome pose significant risk for the progression of many types of chronic illness, including liver disease. Hormones released from adipocytes, adipocytokines, associated with obesity and metabolic syndrome, have been shown to control hepatic inflammation and fibrosis.
Saxena, Neeraj K., Anania, Frank A.
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Noninvasive diagnosis of pediatric nonalcoholic fatty liver disease [PDF]
Korean Journal of Pediatrics, 2013 Because nonalcoholic steatohepatitis can progress towards cirrhosis even in children, early detection of hepatic fibrosis and accurate diagnosis of nonalcoholic fatty liver disease (NAFLD) are important.
Hye Ran Yang
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Association between noninvasive fibrosis markers and cardio-vascular organ damage among adults with hepatic steatosis [PDF]
, 2014 Evidence suggests that advanced fibrosis, as determined by the noninvasive NAFLD fibrosis score (NFS), is a predictor of cardiovascular mortality in individuals with ultrasonography-diagnosed NAFLD. Whether the severity of histology (i.e., fibrosis stage)
Fiorentino, Tv +5 more
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