Renal Tubular Damage Marker, Urinary -acetyl-β-D-Glucosaminidase, as a Predictive Marker of Hepatic Fibrosis in Type 2 Diabetes Mellitus [PDF]
Diabetes & Metabolism Journal, 2022 Background Non-alcoholic steatohepatitis is closely associated with the progression of diabetic kidney disease (DKD) in type 2 diabetes mellitus (T2DM).
Hae Kyung Kim +5 more
doaj +1 more source
Hyaluronic acid levels predict risk of hepatic encephalopathy and liver-related death in HIV/viral hepatitis coinfected patients [PDF]
, 2013 Background: Whereas it is well established that various soluble biomarkers can predict level of liver fibrosis, their ability to predict liver-related clinical outcomes is less clearly established, in particular among HIV/viral hepatitis co-infected ...
Soriano, V +38 more
core +3 more sources
Microcomputed tomography with diffraction-enhanced imaging for morphologic characterization and quantitative evaluation of microvessel of hepatic fibrosis in rats. [PDF]
PLoS ONE, 2013 BACKGROUND:[corrected] Hepatic fibrosis can lead to deformation of vessel morphology and structure. In the present feasibility study, high-resolution computed tomography (CT) using diffraction-enhanced imaging (DEI) was used to represent three ...
Jinghao Duan +4 more
doaj +1 more source
A Selective PPARγ Modulator Reduces Hepatic Fibrosis
Biology, 2020 Hepatic fibrosis is the accumulation of excess collagen as a result of chronic liver injury. If left unabated, hepatic fibrosis can lead to the disruption of the liver architecture, portal hypertension, and increased risk of progression to cirrhosis and ...
Benita L. McVicker +3 more
doaj +1 more source
Fibrosis and hepatic regeneration mechanism [PDF]
Translational Gastroenterology and Hepatology, 2022 Liver cirrhosis is the final stage of continuous hepatic inflammatory activity derived by viral, metabolic or autoimmune origin. In the last years, cirrhosis was considered a unique and static condition; recently was accepted some patients subgroups with different liver injury degrees that coexist under the same diagnosis, with implications about the ...
Esmeralda, Zuñiga-Aguilar +1 more
openaire +2 more sources
Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis [PDF]
, 2010 Background: FibroTest (FT) is the most frequently used serum fibrosis marker and consists of an algorithm of five fibrosis markers (alfa2-macroglobulin, apolipoproteinA1, haptoglobin, GGT, bilirubin). The Enhanced Liver Fibrosis (ELF) test consists of an
Julie Parkes +12 more
core +2 more sources
GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells
JCI Insight, 2021 In response to liver injury, hepatic stellate cells activate and acquire proliferative and contractile features. The regression of liver fibrosis appears to involve the clearance of activated hepatic stellate cells, either by apoptosis or by reversion ...
Noelia Arroyo +10 more
doaj +1 more source
Sympathetic Nervous System Catecholamines and Neuropeptide Y Neurotransmitters Are Upregulated in Human NAFLD and Modulate the Fibrogenic Function of Hepatic Stellate Cells [PDF]
, 2013 Background Sympathetic nervous system (SNS) signalling regulates murine hepatic fibrogenesis through effects on hepatic stellate cells (HSC), and obesity-related hypertension with SNS activation accelerates progression of non-alcoholic fatty liver ...
Vander Borght, S +35 more
core +2 more sources
BMC Surgery, 2021 Background To determine the standard remnant liver volume (SRLV) threshold to avoid postoperative hepatic insufficiency inpatients in different stages of hepatic fibrosis who undergo right hemi-hepatectomy.
Zhiming Zhang +8 more
doaj +1 more source
Medicina, 2021 Background and Objectives: Hepatic diseases are an important public health problem. All patients with chronic hepatitis C virus (HCV) infection receive treatment, regardless of hepatic fibrosis severity.
Oana Irina Gavril +9 more
doaj +1 more source