Results 11 to 20 of about 836,635 (294)
The roles of lncRNA in hepatic fibrosis
Cell & Bioscience, 2018 Increasing evidence indicates that long non-coding RNAs (lncRNAs) regulate gene or protein expression; however, their function in the progression of hepatic fibrosis remains unclear.
Hu Peng +5 more
doaj +2 more sources
A Selective PPARγ Modulator Reduces Hepatic Fibrosis
Biology, 2020 Hepatic fibrosis is the accumulation of excess collagen as a result of chronic liver injury. If left unabated, hepatic fibrosis can lead to the disruption of the liver architecture, portal hypertension, and increased risk of progression to cirrhosis and ...
Benita L. McVicker +3 more
doaj +2 more sources
Reversibility of hepatic fibrosis
, 2014 • Although chronic hepatitis has a diverse aetiology, development of hepatic fibrosis is the universal outcome. • Cirrhosis is considered to be the universal end-stage of chronic liver disease.
Sonneveld, Milan J. +3 more
core +10 more sources
Current Opinion in Gastroenterology, 2009 This review will summarize the most significant work that contributed to the understanding of liver fibrosis progression and resolution, which in turn has yielded new areas of therapeutic targeting.Liver fibrosis is the result of an imbalance between production and dissolution of extracellular matrix.
Jingjing, Jiao +2 more
openaire +3 more sources
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2010 Congenital hepatic fibrosis (CHF) is a rare disease that primarily involves hepatobiliary and renal systems. It is characterized by hepatic fibrosis, portal hypertension and renal cystic disease.
MH Antikchi, R Hoseini
doaj +1 more source
Autophagy in Hepatic Fibrosis [PDF]
BioMed Research International, 2014 Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking.
Yang Song +5 more
openaire +2 more sources
Hepatic Fibrosis in Dogs [PDF]
Journal of Veterinary Internal Medicine, 2018 Abstract Hepatic fibrosis is commonly diagnosed in dogs, often as a sequela to chronic hepatitis (CH). The development of fibrosis is a crucial event in the progression of hepatic disease that is of prognostic value. The pathophysiology of hepatic fibrosis in human patients and rodent models has been studied extensively. Although less
V.M. Eulenberg, J.A. Lidbury
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Autoimmune Hepatitis and Fibrosis
Journal of Clinical Medicine, 2023 Autoimmune hepatitis (AIH) is a chronic immune-inflammatory disease of the liver, generally considered a rare condition. The clinical manifestation is extremely varied and can range from paucisymptomatic forms to severe hepatitis. Chronic liver damage causes activation of hepatic and inflammatory cells leading to inflammation and oxidative stress ...
Rinaldo Pellicano +5 more
openaire +2 more sources
N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1. [In supplement: 11th International Symposium on the Cells of the Hepatic Sinusoid and their Relation to Other Cells] [PDF]
, 2004 Apoptosis of hepatic stellate cells (HSC) has previously been shown to occur during spontaneous resolution of experimental liver fibrosis. TIMP-1 has also been shown to have a key role because of its ability to inhibit apoptosis of HSC via matrix ...
Iredale, John P. +15 more
core +1 more source
Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease. [PDF]
, 2013 Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify new experimental biomarkers for the detection of CFLD.
Richard Schulz +35 more
core +1 more source