Results 21 to 30 of about 187,741 (262)

ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis

open access: yesMolecular Therapy: Nucleic Acids, 2020
Hepatic fibrosis is an inflammatory response that leads to liver cirrhosis in the most advanced condition. Liver cirrhosis is a leading cause of deaths associated with liver diseases; hence, understanding the underlying mechanisms of hepatic fibrosis is ...
Haina Xie   +7 more
doaj   +1 more source

Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2018
Background. The hepatitis B virus infection is a global health issue and the stage of liver fibrosis affects the prognosis in patients with chronic hepatitis B (CHB). We performed the meta-analysis describing diagnostic accuracy of transient elastography
Xiaolong Qi   +8 more
doaj   +1 more source

Conophylline inhibits non-alcoholic steatohepatitis in mice. [PDF]

open access: yesPLoS ONE, 2017
Conophylline (CnP), a vinca alkaloid extracted from the leaves of the tropical plant Ervatamia microphylla, attenuates hepatic fibrosis in mice. However, little is known about whether CnP inhibits steatosis, inflammation, and fibrosis in non-alcoholic ...
Yukiomi Nakade   +13 more
doaj   +1 more source

Microcomputed tomography with diffraction-enhanced imaging for morphologic characterization and quantitative evaluation of microvessel of hepatic fibrosis in rats. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND:[corrected] Hepatic fibrosis can lead to deformation of vessel morphology and structure. In the present feasibility study, high-resolution computed tomography (CT) using diffraction-enhanced imaging (DEI) was used to represent three ...
Jinghao Duan   +4 more
doaj   +1 more source

A Selective PPARγ Modulator Reduces Hepatic Fibrosis

open access: yesBiology, 2020
Hepatic fibrosis is the accumulation of excess collagen as a result of chronic liver injury. If left unabated, hepatic fibrosis can lead to the disruption of the liver architecture, portal hypertension, and increased risk of progression to cirrhosis and ...
Benita L. McVicker   +3 more
doaj   +1 more source

Renal Tubular Damage Marker, Urinary -acetyl-β-D-Glucosaminidase, as a Predictive Marker of Hepatic Fibrosis in Type 2 Diabetes Mellitus [PDF]

open access: yesDiabetes & Metabolism Journal, 2022
Background Non-alcoholic steatohepatitis is closely associated with the progression of diabetic kidney disease (DKD) in type 2 diabetes mellitus (T2DM).
Hae Kyung Kim   +5 more
doaj   +1 more source

GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells

open access: yesJCI Insight, 2021
In response to liver injury, hepatic stellate cells activate and acquire proliferative and contractile features. The regression of liver fibrosis appears to involve the clearance of activated hepatic stellate cells, either by apoptosis or by reversion ...
Noelia Arroyo   +10 more
doaj   +1 more source

Safe standard remnant liver volume after hepatectomy in HCC patients in different stages of hepatic fibrosis

open access: yesBMC Surgery, 2021
Background To determine the standard remnant liver volume (SRLV) threshold to avoid postoperative hepatic insufficiency inpatients in different stages of hepatic fibrosis who undergo right hemi-hepatectomy.
Zhiming Zhang   +8 more
doaj   +1 more source

Role of PNPLA3 in the Assessment and Monitoring of Hepatic Steatosis and Fibrosis in Patients with Chronic Hepatitis C Infection Who Achieved a Sustained Virologic Response

open access: yesMedicina, 2021
Background and Objectives: Hepatic diseases are an important public health problem. All patients with chronic hepatitis C virus (HCV) infection receive treatment, regardless of hepatic fibrosis severity.
Oana Irina Gavril   +9 more
doaj   +1 more source

Exploration of new therapeutic targets for viral hepatic fibrosis, alcoholic hepatic fibrosis, and non-alcoholic hepatic fibrosis

open access: yesAnnals of Translational Medicine, 2022
Hepatic fibrosis is a widespread disease worldwide. Millions of people lose their lives due to hepatic fibrosis every year. The main causes of hepatic fibrosis include viral infection, alcoholism, and obesity. Many studies have been conducted on the single factors that cause hepatic fibrosis; however, no studies have examined whether hepatic fibrosis ...
Wang, Xiaoling   +5 more
openaire   +2 more sources

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