Results 181 to 190 of about 157,614 (311)

Correction: MiR-451a attenuates hepatic steatosis and hepatitis C virus replication by targeting glycerol kinase. [PDF]

J Transl Med
Majumdar S, Chowdhury DR, Chakraborty BC, Chowdhury A, Datta S, Banerjee S.   +5 more
europepmc   +1 more source

Non‐Nutritive Artificial Sweeteners Aspartame and Acesulfame‐K Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease in Male Ldlr−/− Mice

iNew Medicine, EarlyView.
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu, Xiaohua Jiang, Jianping Weng, Suowen Xu   +3 more
wiley   +1 more source

Sucrose but not arsenic induce hepatic steatosis which correlates with calpain-1 inhibition. [PDF]

PLoS One
Velasco M, Ortiz-Huidobro RI, Salazar AM, Hiriart M, Ostrosky-Wegman P, Pánico P.   +5 more
europepmc   +1 more source

Pathogenesis of Hepatic Steatosis

Gastroenterology, 1963
openaire   +2 more sources

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

iNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen, Junda Liu, Xixi Chen, Shi Chen, Yuanyuan Tian, Baoming Wu, Fengxia Yan   +6 more
wiley   +1 more source

Multifocal hepatic steatosis

, 2020
Daniel Bell, Michael Hartung, Mohamed Saber   +2 more
openaire   +2 more sources

Hepatic steatosis in humans is associated with preserved glucagon action on amino acid metabolism. [PDF]

J Clin Invest
Christie HE, Mohan S, Egan AM, Boscolo F, Dalla Man C, Thompson SM, Jundt M, Fleming CJ, Andrews JC, Bailey KR, Jensen MD, Nair KS, Vella A.   +12 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

The nonlinear relationship between the hepatic steatosis index and hypertension: NHANES 2017-2020. [PDF]

Medicine (Baltimore)
Zhao Z, Zhao Z, Ma Y, Huangfu W.
europepmc   +1 more source

Zinc Finger E‐Box Binding Homeobox 1 Mediates Alcohol‐Induced Liver Disease

iNew Medicine, EarlyView.
Alcohol intake leads to the upregulation of ZEB1, which activates the YAP‐IL‐1β/MCP‐1 pathway, resulting in the activation of liver inflammation and the induction of hepatocyte apoptosis. ABSTRACT Hepatitis resulting from alcoholic liver disease (ALD) is an important risk factor for liver cancer. It is essential to understand the role of ALD to prevent
Boyu Zhang, Chunyang Zhang, Xiao Cui, Tao Xu, Xiangpeng Hu, Jiong Gu   +5 more
wiley   +1 more source