Results 231 to 240 of about 157,614 (311)

Factors Associated With Liver Fibrosis in Patients With Type 2 Diabetes and the Predictive Value of CHI3L1

Portal Hypertension &Cirrhosis, EarlyView.
In a retrospective cohort of 236 patients with type 2 diabetes (T2DM), metabolic dysfunction‐associated steatotic liver disease (MASLD) was common and significant fibrosis (liver stiffness measurement [LSM] ≥8 kPa) was frequently observed. Serum chitinase‐3‐like protein 1 (CHI3L1) correlated with LSM (r = 0.48) and remained an independent predictor of ...
Lixia Sun, Shuangshuang Du, Aili Fan, Jiawen Feng, Fei Wang, Jia Lian, Jie Zhang, Baoxin Qian, Qing Ye   +8 more
wiley   +1 more source

Testosterone deficiency synergistically exacerbates fructose-induced hepatic steatosis through gut microbiota and pyruvate in mice. [PDF]

Am J Physiol Endocrinol Metab
Takahashi H, Harada N, Hayamizu Y, Dungubat E, Nakazawa M, Kitakaze T, Sugimoto K, Inui H, Yoshihara E, Takahashi Y, Yamaji R.   +10 more
europepmc   +1 more source

Primary Liver Cancer Trends Worldwide and in China: Analysis of GLOBOCAN 2022 Data and Disease Management Implications

Portal Hypertension &Cirrhosis, EarlyView.
Primary liver cancer remains a major global health burden, with China accounting for over 40% of cases. The predominant etiology is shifting from viral hepatitis to metabolic dysfunction‐associated steatotic liver disease (MASLD), while aflatoxin exposure and unhealthy lifestyles remain important contributors. Comprehensive control strategies—including
Jiayan Yan, Jiayi Wang, Jian Fan, Xinyi Cui, Yuxi Zhang, Xinrong Yang, Qiang Gao, Zhenbin Ding, Zhaoyou Tang, Jia Fan, Dan G. Duda, Ao Huang, Jian Zhou   +12 more
wiley   +1 more source

Hepatic steatosis and fibrosis are associated with metabolic factors rather than endocrine therapy in breast cancer patients. [PDF]

Transl Gastroenterol Hepatol
Nardelli MJ, Monteiro MJSD, Cançado GGL, Cal TCMF, Lima AQR, Pontine VP, Batista MCM, Gelape FA, Vasconcelos JC, Mota LM, Theodoro R, Passos RIFA, Miranda AMC, Rezende AML, Diniz PHC, Gomes JAS, Faria LC, Couto CA.   +17 more
europepmc   +1 more source

Liver Fibrosis Tests and Outcomes of Bariatric Surgery in Morbidly Obese Patients With MASLD

Portal Hypertension &Cirrhosis, EarlyView.
This study validates commonly used non‐invasive tests for liver fibrosis in morbidly obese patients with biopsy‐proven MASLD and evaluates outcomes after bariatric surgery. These non‐invasive tests show low diagnostic accuracy for baseline liver fibrosis, while bariatric surgery significantly improves liver stiffness, metabolic profiles, and ...
Parinda Prathyajuta, Thaninee Prasoppokakorn, Kessarin Thanapirom, Pattharasai Kachornvitaya, Kanokwan Sonsiri, Chonlada Phathong, Arth Khemtong, Suthep Udomsawaengsup, Sombat Treeprasertsuk   +8 more
wiley   +1 more source

Serum osteocalcin is associated with the presence of hepatic steatosis in Chinese patients with chronic hepatitis B. [PDF]

Sci Rep
He Y, Tong L, Zhou Y, Xie F, Tian N, Xie W.   +5 more
europepmc   +1 more source

Fast Quantitative Evaluation of the Amelioration Effect in MASLD During Semaglutide Treatment Using Ultrasound‐Derived Fat Fraction and Fat‐to‐Muscle Ratio

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a chronic liver disease. Research into a feasible, rapid, and effective assessment method is crucial for evaluating the therapeutic effects of semaglutide in MASLD. This prospective study utilized ultrasound‐derived fat fraction measurement and fat‐to‐muscle ratio to evaluate hepatic ...
Yunlin Huang, Ruping Yang, Ying Wang, Xiu‐Yun Lu, Li Wei, Rui Cheng, Juan Cheng, Yijie Qiu, Shiwen Wang, Bo Li, Yi Dong   +10 more
wiley   +1 more source

Assessment of the Diagnostic Performance and Clinical Impact of AI in Hepatic Steatosis: Systematic Review and Meta-Analysis.

J Med Internet Res
Song J, Liu D, Li J, Cong H, Deng R, Lu Y, Sun J, Zhang J.   +7 more
europepmc   +1 more source

Adipocyte-specific deletion of gp130 prevents ketogenic diet-induced hepatic steatosis. [PDF]

Hepatol Commun
Senkalfa B, Gloor M, Podlaszewski R, Dewal RS, Horvath C, Efthymiou V, Ghosh A, Wueest S, Konrad D, Wolfrum C, Challa TD.   +10 more
europepmc   +1 more source