Results 51 to 60 of about 367,035 (204)

The impact of hepatic steatosis on outcomes of colorectal cancer patients with liver metastases: A systematic review and meta-analysis

open access: yesFrontiers in Medicine, 2022
BackgroundIt is unclear how hepatic steatosis impacts patient prognosis in the case of colorectal cancer with liver metastases (CRLM). The purpose of this review was to assess the effect of hepatic steatosis on patient survival and disease-free survival (
Shengjie Yang, Renze Peng, Leiming Zhou
doaj   +1 more source

Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice

open access: yes, 2022
Qingjuan Zuo,1,2 Guorui Zhang,1,3 Lili He,2 Sai Ma,4 Huijuan Ma,5 Jianlong Zhai,6 Zhongli Wang,7 Tingting Zhang,2 Yan Wang,2 Yifang Guo1,2 1Department of Internal Medicine, Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Department ...
Zhang G   +9 more
core  

Noninvasive Assessment of Hepatic Steatosis [PDF]

open access: yesClinical Gastroenterology and Hepatology, 2009
Hepatic steatosis, the accumulation of lipids within hepatocytes, is a common condition. The prevalence of its most frequent manifestation, nonalcoholic fatty liver disease (NAFLD), has been estimated to be as high as 35% in some populations. Currently, liver biopsy is the gold standard for the diagnosis and assessment of severity of hepatic steatosis,
Sameer M, Mazhar   +2 more
openaire   +2 more sources

Factors affecting the diagnostic accuracy of ultrasonography in assessing the severity of hepatic steatosis

open access: yesJournal of the Formosan Medical Association, 2014
Ultrasonography has long been recognized as a useful tool for detecting hepatic steatosis in clinical practice. However, whether it can assess the severity of hepatic steatosis and which factors affect its diagnostic accuracy remain unclear.
Chia-Chi Wang   +7 more
doaj   +1 more source

Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human [PDF]

open access: yes, 2009
Studies in mice have shown that PPARalpha is an important regulator of hepatic lipid metabolism and the acute phase response. However, little information is available on the role of PPARalpha in human liver.
Rakhshandehroo, M.   +15 more
core   +1 more source

Association of insulin resistance indicators with hepatic steatosis and fibrosis in patients with metabolic syndrome

open access: yesBMC Gastroenterology
Background To investigate the association of four insulin resistance (IR) indicators with hepatic steatosis and fibrosis in patients with metabolic syndrome (MetS), as well as to compare the diagnostic value of these indicators in identifying hepatic ...
Tzu-chia Kuo   +5 more
doaj   +1 more source

Clinical and Anamnestic Features of Hepatic Steatosis in Children

open access: yesGastroenterologìa, 2015
The article is devoted to the study of clinical and anamnestic features of hepatic steatosis in children. The results of a comparative analysis of survey data of patients with evidence of hepatic steatosis and patients without steatosis were shown.
N.Yu. Zavgorodnia   +4 more
doaj   +1 more source

Non-alcoholic steatohepatitis and progression of carotid atherosclerosis in patients with type 2 diabetes: a Korean cohort study

open access: yesCardiovascular Diabetology, 2020
Background There is increasing concern regarding cardiovascular risk in individuals with non-alcoholic fatty liver disease. This study was conducted to evaluate whether hepatic steatosis with or without fibrosis is associated with the progression of ...
Hyeok-Hee Lee   +10 more
doaj   +1 more source

Genetic Ablation of Solute Carrier Family 7a3a Leads to Hepatic Steatosis in Zebrafish During Fasting

open access: yes, 2014
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder caused by abnormal lipid metabolisms, such as reduced hepatic fatty acid oxidation (FAO), but intracellular control of FAO under physio-and pathological conditions remains
Yang, Xiaojie   +7 more
core   +1 more source

Glucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease [PDF]

open access: yes, 2011
The polymorphism, KLF6-IVS1-27A, in the Krüppel-like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is associated with delayed histological progression of nonalcoholic fatty liver disease (NAFLD).
Gastaldelli, Amalia   +80 more
core   +1 more source

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