Results 21 to 30 of about 70,274 (304)

Reelin expression in human liver of patients with chronic hepatitis C infection

European Journal of Histochemistry, 2017
Reelin is a secreted extracellular glycoprotein that plays a critical role during brain development. Several studies have described Reelin expression in hepatic stellate cells of the human liver. In order to investigate the possible role of Reelin in the
Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini   +11 more
doaj   +1 more source

A fresh look at augmenter of liver regeneration in rats. [PDF]

, 1999
Augmenter of liver regeneration (ALR) is a hepatotrophic protein originally identified by bioassay in regenerating rat and canine livers following partial hepatectomy and in the hyperplastic livers of weanling rats, but not in resting adult livers.
Abyss, Armendariz-Borunda, Ascoli, Blomquist, Bucher, Bucher, Bucher, Dallman, Dallman, Davies, DeHemptinne, Earp, Evarts, Fausto, Fausto, Fausto, Francavilla, Francavilla, Francavilla, Francavilla, Francavilla, Francavilla, Francavilla, Francavilla, Francavilla, Gabriel, Gandhi, Gandhi, Geerts, Giorda, Grisham, Hagiya, Hagiya, Harding, Higgins, Hully, Itoh, Koch, LaBrecque, Lambotte, Leffert, Leffert, Makowka, Marchioro, Marchioro, Mars, Masumoto, Mazzaferro, McJunkin, Mead, Meyer, Michalopoulos, Michalopoulos, Naldini, Pause, Rilo, Rubin, Russell, Sakamoto, Sasaki, Schirmacher, Shaw, Siekierka, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Steer, Steiner, Steiner, Subbotin, Teir, Terblanche, Vujanovic, Wang, Wang, Webber, Webber, Yamate, Younger, Zindi   +86 more
core   +1 more source

Toll-Like Receptor Signaling and Liver Fibrosis

Gastroenterology Research and Practice, 2010
Liver fibrosis occurs as a wound-healing scar response following acute and chronic liver inflammation including alcoholic liver disease, non-alcoholic steatohepatitis, hepatitis B and C, and autoimmune hepatitis.
Tomonori Aoyama, Yong-Han Paik, Ekihiro Seki   +2 more
doaj   +1 more source

Storage of vitamin A in extrahepatic stellate cells in normal rats

Journal of Lipid Research, 1997
In mammals, vitamin A is primarily stored as retinyl esters in hepatic stellate cells under normal dietary intake of the vitamin. Previously, extrahepatic vitamin A-storing stellate cells have only been identified in animals maintained on a vitamin A ...
N E Nagy, K B Holven, N Roos, H Senoo, N Kojima, K R Norum, R Blomhoff   +6 more
doaj   +1 more source

Playing Jekyll and Hyde—The Dual Role of Lipids in Fatty Liver Disease

Cells, 2020
Lipids play Jekyll and Hyde in the liver. On the one hand, the lipid-laden status of hepatic stellate cells is a hallmark of healthy liver. On the other hand, the opposite is true for lipid-laden hepatocytes—they obstruct liver function.
Martijn R. Molenaar, Louis C. Penning, J. Bernd Helms   +2 more
doaj   +1 more source

Inhibition of vascular endothelial growth factor signaling facilitates liver repair from acute ethanol-induced injury in zebrafish

Disease Models & Mechanisms, 2016
Alcoholic liver disease (ALD) results from alcohol overconsumption and is among the leading causes of liver-related morbidity and mortality worldwide. Elevated expression of vascular endothelial growth factor (VEGF) and its receptors has been observed in
Changwen Zhang, Jillian L. Ellis, Chunyue Yin   +2 more
doaj   +1 more source

Heparanase and macrophage interplay in the onset of liver fibrosis [PDF]

, 2017
The heparan sulfate endoglycosidase heparanase (HPSE) is involved in tumor growth, chronic inflammation and fibrosis. Since a role for HPSE in chronic liver disease has not been demonstrated to date, the current study was aimed at investigating the ...
Crescenzi, Marika, Floreani, Annarosa, Masola, Valentina, Onisto, Maurizio, Russo, Francesco Paolo, Secchi, Maria Francesca   +5 more
core   +2 more sources

Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. [PDF]

, 2018
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on which cancer develops.
Amicone, Laura, Marchetti, Alessandra
core   +1 more source

Levels of hepatic Th17 cells and regulatory T cells upregulated by hepatic stellate cells in advanced HBV-related liver fibrosis

Journal of Translational Medicine, 2017
Background Liver fibrosis which mainly occurs upon chronic hepatitis virus infection potentially leads to portal hypertension, hepatic failure and hepatocellular carcinoma.
Xiaoyan Li, Yujie Su, Xuefeng Hua, Chan Xie, Jing Liu, Yuehua Huang, Liang Zhou, Min Zhang, Xu Li, Zhiliang Gao   +9 more
doaj   +1 more source

NOX as a Therapeutic Target in Liver Disease

Antioxidants, 2022
The nicotinamide adenine dinucleotide phosphate hydrogen oxidase (NADPH oxidase or NOX) plays a critical role in the inflammatory response and fibrosis in several organs such as the lungs, pancreas, kidney, liver, and heart. In the liver, NOXs contribute,
Deyamira Matuz-Mares, Héctor Vázquez-Meza, María Magdalena Vilchis-Landeros   +2 more
doaj   +1 more source