Results 301 to 310 of about 79,018 (355)

The Non-Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF-β-E2F1 Axis. [PDF]

open access: yesAdv Sci (Weinh)
Zhang J   +10 more
europepmc   +1 more source

The adiponectin-PPARγ axis in hepatic stellate cells regulates liver fibrosis. [PDF]

open access: yesCell Rep
Zhao S   +16 more
europepmc   +1 more source

Pro-inflammatory effects of endogenous and recombinant MDA-7/IL-24 with RGD peptide on human hepatic stellate cells. [PDF]

open access: yesSci Rep
Daneshparvar A   +6 more
europepmc   +1 more source

Intercellular communication between hepatic stellate cells and myofibroblasts mediated by osteopontin and FGF18 promotes liver fibrosis. [PDF]

open access: yesiScience
Seki T   +8 more
europepmc   +1 more source

Mechanisms of hepatic stellate cell activation

Nature Reviews Gastroenterology & Hepatology, 2017
Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic liver disease and NASH. Activation of hepatic stellate cells (HSCs) - transdifferentiation of quiescent, vitamin-A-storing cells into proliferative, fibrogenic ...
Takuma, Tsuchida, Scott L, Friedman
openaire   +4 more sources

Transcriptional regulation of hepatic stellate cells

Advanced Drug Delivery Reviews, 2009
Hepatic stellate cell (HSC) activation is a process of cellular transdifferentiation in which, upon liver injury, the quiescent vitamin A storing perisinusoidal HSC is converted into a wound-healing myofibroblast and acquires potent pro-inflammatory and pro-fibrogenic activities.
Mann J, Mann DA
openaire   +5 more sources

Studying Hepatic Stellate Cell Senescence

2023
Hepatic stellate cells (HSCs) are the key effector cells in liver fibrosis. They are the main producers of excessive amounts of extracellular matrix components during fibrogenesis and therefore a potential target for the treatment of liver fibrosis.
Sandra A, Serna-Salas   +4 more
openaire   +3 more sources

Cryopreservation of hepatic stellate cells

Journal of Hepatology, 2006
Isolated rat hepatic stellate cells (HSC) are taken as a valuable in vitro model to study hepatic fibrogenesis, biotransformation of pharmaceutics, gene expression, transcription factors controlling HSC behaviour, and for the establishment of long-term cultures. Consequently, methods for the isolation and maintenance of HSC cultures are well documented.
Svenja, Neyzen   +6 more
openaire   +2 more sources

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