Results 251 to 260 of about 1,894,434 (309)
Review of animal experimentation in infectious hepatitis and in serum hepatitis.
The Yale journal of biology and medicine, 2007 openaire +1 more source
Animal Models for Hepatitis E Virus
, 2016 Animal models are one of the most important tools in the study of human hepatitis E virus (HEV) infection. They are particularly important in light of the major limitations of the cell culture system for HEV. Besides nonhuman primates, which are extremely valuable because of their susceptibility to HEV genotypes 1-4, animals like swine, rabbit, and ...
Lin, Wang, Ling, Wang
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Animal models for autoimmune hepatitis
Autoimmunity Reviews, 2007The liver is the target of adverse immune reactions in three putative autoimmune diseases: autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). These three diseases can be distinguished by clinical, histological, and immunological features.
Urs, Christen +2 more
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Animal Models for Hepatitis E Virus
2023Animal models are one of the most important tools in the study of human hepatitis E virus (HEV) infection. They are particularly important in light of the major limitations of the cell culture system for HEV. Besides nonhuman primates, which are extremely valuable because of their susceptibility to HEV genotypes 1-4, animals like swine, rabbit, and ...
Tianxu, Liu, Lin, Wang, Ling, Wang
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2013
Hepatitis C remains a global epidemic. Approximately 3 % of the world's population suffers from chronic hepatitis C, which is caused by hepatitis C virus (HCV)-a positive sense, single-stranded RNA virus of the Flaviviridae family. HCV has a high propensity for establishing a chronic infection. If untreated chronic HCV carriers can develop severe liver
Eva, Billerbeck +4 more
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Hepatitis C remains a global epidemic. Approximately 3 % of the world's population suffers from chronic hepatitis C, which is caused by hepatitis C virus (HCV)-a positive sense, single-stranded RNA virus of the Flaviviridae family. HCV has a high propensity for establishing a chronic infection. If untreated chronic HCV carriers can develop severe liver
Eva, Billerbeck +4 more
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New Animal Models for Autoimmune Hepatitis
Seminars in Liver Disease, 2009Autoimmune hepatitis (AIH) is often diagnosed late in the disease course and usually requires lifelong immunosuppressive therapy. Unfortunately, the etiology of the disease and the mechanisms leading to the autoimmune destruction of the liver parenchyma are only poorly understood.
Urs, Christen +2 more
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Animal models of fulminant hepatic failure
Digestive Diseases and Sciences, 1991The six requirements for a satisfactory animal model of fulminant hepatic failure are reversibility, reproducibility, death from liver failure, a therapeutic window, a large animal model, and minimal hazard to personnel. Different models may be required to evaluate the various types of liver failure seen in man.
J, Terblanche, R, Hickman
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Animal models of autoimmune hepatitis
Expert Review of Gastroenterology & Hepatology, 2010Animal models of autoimmune hepatitis have been important in defining pathogenic mechanisms, and they promise to aid in the evaluation of new molecular and cellular treatments. They have evolved from models based on crude liver homogenates that produced a transient hepatitis to models that express antibodies to human antigens, manifest liver ...
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Hepatitis E viruses in humans and animals
Animal Health Research Reviews, 2004AbstractHepatitis E virus (HEV) is an emerging pathogen belonging to a newly recognized family of RNA viruses (Hepeviridae). HEV is an important enterically transmitted human pathogen with a worldwide distribution. It can cause sporadic cases as well as large epidemics of acute hepatitis. Epidemics are primarily waterborne in areas where water supplies
S Denise, Goens, Michael L, Perdue
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Animal Models of Autoimmune Hepatitis
Seminars in Liver Disease, 2002Autoimmune hepatitis (AIH) is difficult to study in humans because of the late diagnosis, the heterogenic genetic background and the lack of tissue specimens. Therefore, animal models have been used for more than 90 years to study liver-specific immune regulation.
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