Results 81 to 90 of about 1,894,434 (309)

Hepatitis risk assessment tool [PDF]

"Hepatitis" means inflammation of the liver and is usually caused by a virus. In the U.S., the most common types are Hepatitis A, Hepatitis B, and Hepatitis C.

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Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation

Advanced Science, EarlyView.
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan, Ting‐Hui Lee, Tzu‐Ning Peng, Eva Yi‐Hsuan Wu, Yu‐Ting Chiu, Chih‐Chien Chiu, Hong Vinh Nguyen, Yuan‐Shao Pao, Ming‐Hong Chao, Richard Kuan‐Lin Lee, Han‐Chung Wu, Lily Hui‐Ching Wang   +11 more
wiley   +1 more source

Pharmacothera-peutic activity Lomatogonium Carinthiacum extract at experimental hepatitis

Acta Biomedica Scientifica, 2013
Pharmacotherapeutic efficiency of the dry extract from Lomatogonium carinthiacum in toxic hepatitis was studied. Experimental hepatitis was caused by the introduction of tetracycline hydrochloride to Wistar white rats in the dose of 1,0 g/kg of the ...
A. V. Fedorov, S. M. Nikolaev, Z. G. Sambuyeva, Ya. G. Razuvaeva, A. A. Toropova, E. V. Ferubko   +5 more
doaj  

Counselling services for persons with Hepatitis C

, 2007
Consultative Council on Hepatitis C ...
Consultative Council on Hepatitis C
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Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

PHARMACOTHERAPY OF EXPERIMENTAL HEPATITIS BY LOMATOGONIUM CARINTHIACUM EXTRACT

Acta Biomedica Scientifica, 2014
Pharmacotherapeutic efficiency of the dry extract from Lomatogonium carinthiacum in toxic hepatitis was studied. Experimental hepatitis was caused by the introduction of tetracycline hydrochloride to Wistar white rats in the dose of 1.0 g/kg of the ...
A. V. Fedorov, S. M. Nikolaev, Z. G. Sambuyeva, Y. G. Razuvaeva, A. A. Toropova, E. V. Ferubko   +5 more
doaj  

Natural Hepacivirus Infection in Tree Shrews: A Call for Routine Screening in Hepatitis Virus Research

Viruses
Hepatitis viruses continue to pose major global health challenges, necessitating the development of reliable and well-characterized experimental models.
Mohammad Enamul Hoque Kayesh, Takahiro Sanada, Michinori Kohara, Kyoko Tsukiyama-Kohara   +3 more
doaj   +1 more source

Liver chimeric mice with tupaia hepatocyte transplantation as an animal model for hepatitis B virus infection and antiviral therapy

Biosafety and Health, 2019
The human liver chimeric mouse is a milestone animal model for hepatitis B virus (HBV) infection. Such mice with primary human hepatocyte (PHH) transplantation are adequate to support chronic HBV infection for several weeks and to evaluate antiviral ...
Lunzhi Yuan, Yao Chen, Xuan Liu, Yali Zhang, Ming Zhou, Kun Wu, Quan Yuan, Tong Cheng, Ningshao Xia   +8 more
doaj   +1 more source

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm, Kathrin Hueging, Michael Ott, Hueging, Kathrin, Brohm, Christiane, Ott, Michael, Bitzegeio, Julia, Dorothea Bankwitz, Herrmann, Eva, Sibylle Haid, Thomas Pietschmann, Mirjam B. Zeisel, Baumert, Thomas F, Iken, Marcus, Haid, Sibylle, Marcus Iken, Julia Bitzegeio, Thomas F. Baumert, Zeisel, Mirjam B, Thomas F Baumert, Mirjam B Zeisel, Eva Herrmann, Baumert, Thomas, Bankwitz, Dorothea, Zeisel, Mirjam B., Pietschmann, Thomas   +25 more
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Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source