Results 11 to 20 of about 553,897 (314)

Chronic hepatitis [PDF]

Postgraduate Medicine, 1974
Chronic hepatitis may be viral or "lupoid" or may be related to drug use, alcoholism, or Wilson's disease. This article outlines the routine and special laboratory investigations that are indicated when the presence of chronic hepatitis is suspected from symptoms referable to the liver or from biochemical or physical abnormalities in an asymptomatic ...
openaire   +5 more sources

Different profiles of neurocognitive impairment in patients with hepatitis B and C virus infections

Scientific Reports, 2022
The direct impact of chronic hepatitis B and hepatitis C on neurocognition remains elusive due to the frequent comorbidities, and the domains of the neurocognitive functions affected have rarely been investigated comprehensively.
Chun-Hsiang Tan, Meng-Chia Chang, Wei-Fang Tsai, Wan-Long Chuang, Jee-Fu Huang, Zu-Yau Lin, Chia-Yen Dai, Ming-Lun Yeh, Chi-Ting Li, Rwei-Ling Yu   +9 more
doaj   +1 more source

The evaluation of liver fibrosis regression in chronic hepatitis C patients after the treatment with direct-acting antiviral agents – A review of the literature [PDF]

, 2019
The second-generation of direct-acting antiviral agents are the current treatment for chronic viral hepatitis C infection. To evaluate the regression of liver fibrosis in patients receiving this therapy, liver biopsy remains the most accurate method, but
Alexescu, Teodora G, Cibu, Bianca A, Ciulei, George, Coste, Sorina C, Cozma, Angela, Mureșan, Flaviu, Negrean, Vasile, Orasan, Olga H, Ovidiu, Fabian, Pfingstgraf, Iulia O, Popovici, Ionela E, Tarmure, Simina F, Taut, Adela V. S   +12 more
core   +3 more sources

Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-Naïve chronic HBV patients [PDF]

, 2013
Background: Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness.
Abedi, F., Alavian, S.M., Ataei, B., Azad, T.M., Daram, M., Fazeli, Z., Ghamari, S., Goodarzi, Z., Jazayeri, S.M., Judaki, M.A., Kalantari, E., Karimzadeh, H., Keyvani, H., Khedive, A., Mahabadi, M., Mahmoodi, M., Malekzadeh, R., Mansour-Ghanaei, F., Montazeri, G., Moradi, A., Nejatizadeh, A., Norouzi, M., Pourhosseingholi, M.A., Rafatpanah, H., Ramezani, F., Saberfar, E., Saberfiroozi, M., Samimirad, K., Sanei-Moghaddam, I., Sarizadeh, G., Sayad, B., Somi, M.H., Yaran, M., Ziee, M.   +33 more
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Quality of life in patients with chronic hepatitis C [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2011
Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared ...
Pavić Slađana, Delić Dragan, Simonović Jasmina, Švirtlih Neda   +3 more
doaj   +1 more source

ETIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE KHOREZM REGION OF UZBEKISTAN

Байкальский медицинский журнал, 2023
A study of the etiological structure of chronic viral hepatitis is presented, taking into account the assessment of the stage of the pathological process and the genotypic affiliation of pathogens in the Khorezm region of the Republic of Uzbekistan.
Shavkat R. Yusupov, Kurban A. Aitov, Evgeny D. Savilov, Dilfuza K. Abdullayeva, Safar E. Umirov   +4 more
doaj   +1 more source

A deep learning model to predict RNA-Seq expression of tumours from whole slide images

Nature Communications, 2020
RNA-sequencing of tumour tissue can provide important diagnostic and prognostic information but this is costly and not routinely performed in all clinical settings. Here, the authors show that whole slide histology slides—part of routine care—can be used
Benoît Schmauch, Alberto Romagnoni, Elodie Pronier, Charlie Saillard, Pascale Maillé, Julien Calderaro, Aurélie Kamoun, Meriem Sefta, Sylvain Toldo, Mikhail Zaslavskiy, Thomas Clozel, Matahi Moarii, Pierre Courtiol, Gilles Wainrib   +13 more
doaj   +1 more source

Chronic hepatitis B [PDF]

Current Treatment Options in Gastroenterology, 2001
All patients who test positive for hepatitis B virus (HBV) surface antigen (HBsAg) should be evaluated to determine the activity and severity of the infection. Assessment includes tests of disease activity (aspartate transaminase, alanine aminotransferase), tests of liver function (bilirubin, albumin, prothrombin time), and tests of replication status (
Lok, Anna Suk-Fong, McMahon, Brian J.
openaire   +7 more sources

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

Nature Communications, 2016
Cyclophilins play a key role in the life cycle of many viruses and represent important drug targets for broad-spectrum antiviral therapies. Here, the authors use fragment-based drug discovery to develop non-peptidic inhibitors of human cyclophilins with ...
Abdelhakim Ahmed-Belkacem, Lionel Colliandre, Nazim Ahnou, Quentin Nevers, Muriel Gelin, Yannick Bessin, Rozenn Brillet, Olivier Cala, Dominique Douguet, William Bourguet, Isabelle Krimm, Jean-Michel Pawlotsky, Jean- François Guichou   +12 more
doaj   +1 more source

Risk factors and outcome among a large patient cohort with community-acquired acute hepatitis C in Italy [PDF]

, 2006
BACKGROUND: The epidemiology of acute hepatitis C has changed during the past decade in Western countries. Acute HCV infection has a high rate of chronicity, but it is unclear when patients with acute infection should be treated.
Ancarani, Fausto, Antonucci, Giorgio, Babudieri, Sergio, Cariti, Giuseppe, Di Marco, Vito, Fabris, Paolo, Ferrari, Carlo, Francavilla, Ruggero, Massari, Marco, Medda, Emanuela, Pastore, Giuseppe, Santantonio, Teresa, Scotto, Gaetano, Stroffolini, Tommaso, Toti, Mario   +14 more
core   +2 more sources