Results 21 to 30 of about 326,843 (184)

Chronic Hepatitis C [PDF]

open access: yesGut and Liver, 2011
The goal of antiviral therapy for patients with chronic hepatitis C virus (HCV) infection is to attain a sustained virologic response (SVR), which is defined as undetectable serum HCV-RNA levels at 6 months after the cessation of treatment. Major improvements in antiviral therapy for chronic hepatitis C have occurred in the past decade. The addition of
Jang, Jae Young, Chung, Raymond T.
openaire   +3 more sources

A deep learning model to predict RNA-Seq expression of tumours from whole slide images

open access: yesNature Communications, 2020
RNA-sequencing of tumour tissue can provide important diagnostic and prognostic information but this is costly and not routinely performed in all clinical settings. Here, the authors show that whole slide histology slides—part of routine care—can be used
Benoît Schmauch   +13 more
doaj   +1 more source

Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities

open access: yesNature Communications, 2016
Cyclophilins play a key role in the life cycle of many viruses and represent important drug targets for broad-spectrum antiviral therapies. Here, the authors use fragment-based drug discovery to develop non-peptidic inhibitors of human cyclophilins with ...
Abdelhakim Ahmed-Belkacem   +12 more
doaj   +1 more source

Reações cutâneas graves adversas a drogas: aspectos relevantes ao diagnóstico e ao tratamento - Parte II Severe cutaneous adverse drug reactions: relevant aspects to diagnosis and treatment - Part II

open access: yesAnais Brasileiros de Dermatologia, 2004
As reações cutâneas graves adversas à droga são as que geralmente necessitam de internação hospitalar, por vezes em unidade de terapia intensiva ou de queimados, com observação minuciosa dos sinais vitais e da função de órgãos internos.
Paulo Ricardo Criado   +4 more
doaj   +1 more source

Lipoprotein Receptors and Lipid Enzymes in Hepatitis C Virus Entry and Early Steps of Infection

open access: yesScientifica, 2012
Viruses are obligate intracellular agents that depend on host cells for successful propagation, hijacking cellular machineries to their own profit. The molecular interplay between host factors and invading viruses is a continuous coevolutionary process ...
Eve-Isabelle Pécheur
doaj   +1 more source

Quality of life in patients with chronic hepatitis C [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2011
Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared ...
Pavić Slađana   +3 more
doaj   +1 more source

ETIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE KHOREZM REGION OF UZBEKISTAN

open access: yesБайкальский медицинский журнал, 2023
A study of the etiological structure of chronic viral hepatitis is presented, taking into account the assessment of the stage of the pathological process and the genotypic affiliation of pathogens in the Khorezm region of the Republic of Uzbekistan.
Shavkat R. Yusupov   +4 more
doaj   +1 more source

Clinical and psychopathological features of the course and outcome of the first psychotic episode.

open access: yesJournal of Education, Health and Sport, 2023
Recently it has been established that cytokines are involved in the regulation of the body’s defense reactions in response to a pathogen and form an independent system  for regulating homeostasis.
Yuri Bazhora   +4 more
doaj   +1 more source

Improving Therapeutic Vaccination against Hepatitis B—Insights from Preclinical Models of Immune Therapy against Persistent Hepatitis B Virus Infection

open access: yesVaccines, 2021
Chronic hepatitis B affects more than 250 million individuals worldwide, putting them at risk of developing liver cirrhosis and liver cancer. While antiviral immune responses are key to eliminating hepatitis B virus (HBV) infections, insufficient ...
Percy A. Knolle   +4 more
doaj   +1 more source

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