Results 21 to 30 of about 326,843 (184)
The goal of antiviral therapy for patients with chronic hepatitis C virus (HCV) infection is to attain a sustained virologic response (SVR), which is defined as undetectable serum HCV-RNA levels at 6 months after the cessation of treatment. Major improvements in antiviral therapy for chronic hepatitis C have occurred in the past decade. The addition of
Jang, Jae Young, Chung, Raymond T.
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A deep learning model to predict RNA-Seq expression of tumours from whole slide images
RNA-sequencing of tumour tissue can provide important diagnostic and prognostic information but this is costly and not routinely performed in all clinical settings. Here, the authors show that whole slide histology slides—part of routine care—can be used
Benoît Schmauch +13 more
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Cyclophilins play a key role in the life cycle of many viruses and represent important drug targets for broad-spectrum antiviral therapies. Here, the authors use fragment-based drug discovery to develop non-peptidic inhibitors of human cyclophilins with ...
Abdelhakim Ahmed-Belkacem +12 more
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As reações cutâneas graves adversas à droga são as que geralmente necessitam de internação hospitalar, por vezes em unidade de terapia intensiva ou de queimados, com observação minuciosa dos sinais vitais e da função de órgãos internos.
Paulo Ricardo Criado +4 more
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Lipoprotein Receptors and Lipid Enzymes in Hepatitis C Virus Entry and Early Steps of Infection
Viruses are obligate intracellular agents that depend on host cells for successful propagation, hijacking cellular machineries to their own profit. The molecular interplay between host factors and invading viruses is a continuous coevolutionary process ...
Eve-Isabelle Pécheur
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Quality of life in patients with chronic hepatitis C [PDF]
Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared ...
Pavić Slađana +3 more
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ETIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE KHOREZM REGION OF UZBEKISTAN
A study of the etiological structure of chronic viral hepatitis is presented, taking into account the assessment of the stage of the pathological process and the genotypic affiliation of pathogens in the Khorezm region of the Republic of Uzbekistan.
Shavkat R. Yusupov +4 more
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Clinical and psychopathological features of the course and outcome of the first psychotic episode.
Recently it has been established that cytokines are involved in the regulation of the body’s defense reactions in response to a pathogen and form an independent system for regulating homeostasis.
Yuri Bazhora +4 more
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Chronic hepatitis B affects more than 250 million individuals worldwide, putting them at risk of developing liver cirrhosis and liver cancer. While antiviral immune responses are key to eliminating hepatitis B virus (HBV) infections, insufficient ...
Percy A. Knolle +4 more
doaj +1 more source

