Results 71 to 80 of about 553,897 (314)
Advanced Science, EarlyView.TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang +12 more
wiley +1 more source
Prevalence of hepatitis C virus infection in patients with cardiomyopathy
Annals of Hepatology, 2009 Chronic hepatitis C can be associated with extrahepatic manifestations; thus, we explored the association of this viral infection with dilated cardiomyopathy in a group of sixty-three patients with a cardiac ejection fraction of less than 40% determined ...
Vijaya Boyella; +5 more
doaj +1 more source
International Journal of Clinical Practice, 2000 SUMMARYBoth hepatitis B and hepatitis C are spread parenterally. Chronic hepatitis C is fast becoming the leading indication for liver transplantation. Most infected patients go on to develop chronic hepatitis, with approximately 20% developing liver cirrhosis or hepatocellular carcinoma after 20 years.
G, Alexander, K, Walsh
openaire +2 more sources
Advanced Science, EarlyView.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Interferon-α for Immune Modulation in Chronic Hepatitis B Toward Functional Cure
VirusesChronic hepatitis B (CHB) remains a major global health challenge, largely due to the persistence of covalently closed circular DNA (cccDNA) and impaired host immunity.
Asha Ashuo +3 more
doaj +1 more source
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2019 慢性肾脏病（chronic kidney disease,CKD）是我国重要的公共健康问题,流行率约10.8%,据此推算,我国成人CKD患者约1.2亿[1]。根据肾小球滤过率（estimated glomerular filtration rate,eGFR）,CKD可分为1～5期[2]。CKD患者免疫功能低下,易受细菌、病毒及其他病原体感染,而血液透析患者更是丙型肝炎病毒（hepatitis C virus,HCV）感染的高危人群 ...
The committee of expert consensus for the diagnosis and treatment of chronic kidney disease with hepatitis Cinfection
doaj
Hepatite crónica: o espectro etiológico. Implicações para o tratamento.
Acta Médica Portuguesa, 1993 The prevalence of chronic hepatitis and its different aetiologies was studied in all patients above 10 years of age seen in the specialised outpatient clinic of our hospital over a 3 year period.
J Velosa +4 more
doaj +1 more source
Economic evaluation of HBV vaccination: a systematic review of recent publications (2000-2013). [PDF]
, 2016 Aim: To conduct a systematic review of the economic evaluations (EE) of HBV vaccination, taking also into account the studies published in the new millennium. Methods: An extensive scientific literature review was conducted using two electronic medical
COLAMESTA, VITTORIA +6 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source