Results 211 to 220 of about 104,518 (264)

The Human Liver-uPA-SCID Mouse. A Small Animal Model for the study of viral hepatitis.

, 2006
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Worldwide diversity of hepatitis A and E viruses in urban wastewater

de Graaf M, Worp N, Fajar P, Nieuwenhuijse D, Schapendonk C, Prasad D, Brinch C, Jensen EEB, Munk P, Otani S, Lara RWI, Hulland E, Geilvoet S, Hendriksen R, Remondini D, Csabai I, Aarestrup F, Munnink BO, Koopmans M.   +18 more
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Viral hepatitis, type B, in experimental animals

The American Journal of the Medical Sciences, 1975
Evidence of natural infection with hepatitis B virus (HBV) in chimpanzees was followed by demonstration that this species provides a highly sensitive animal model system for experimental type B hepatitis. With rare exceptions, inoculation of sero-negative chimps with materials containing infectious HBV produces serologic evidence of infection including
L F, Barker, J E, Maynard, R H, Purcell, J H, Hoofnagle, K R, Berquist, W T, London   +5 more
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Cell Culture and Animal Models of Viral Hepatitis. Part I: Hepatitis B

Lab Animal, 2004
Despite the existence of a preventative vaccine, HBV represents a substantial threat to public health, suggesting the need for research to develop new treatments to combat the disease. The authors review the available in vitro and in vivo models, including recently developed transgenic and chimeric mouse models.
Chandan, Guha, Sankar, Mohan, Namita, Roy-Chowdhury, Jayanta, Roy-Chowdhury   +3 more
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Cell Culture Models and Animal Models of Viral Hepatitis. Part II: Hepatitis C

Lab Animal, 2005
The lack of a preventive vaccine, coupled with common unresponsiveness to treatment and coinfection with HIV, has made HCV a major threat to public health. The authors review in vitro and in vivo models that are being used to study HCV and to develop new treatments and preventive measures.
Chandan, Guha, Sung-W, Lee, Namita Roy, Chowdhury, Jayanta Roy, Chowdhury   +3 more
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High seroprevalence of viral hepatitis among animal handlers in Abeokuta, Ogun State, Nigeria

Journal of Immunoassay and Immunochemistry, 2020
Viral hepatitis is a deadly disease which can manifest as acute, chronic, hepatocellular carcinoma, and liver failure. Information about hepatitis is scarce among animal handlers. Due to Federal Government of Nigeria diversification programmes, many people are now involved in animal farming which can make them susceptible to viral hepatitis. This study
A S, Oluremi, T A, Ajadi, O O, Opaleye, O A T, Alli, D O, Ogbolu, S S, Enitan, O O, Alaka, A A, Adelakun, I O, Adediji, A O, Ogunleke, I E, Suleiman, E A, Olowoyeye, O O, Adewumi, A T, Ojo, O O, Adeyeye-Adetunji, S S, Hammed   +15 more
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Serologic and animal inoculation studies of a communal outbreak of viral hepatitis, type A

The American Journal Of The Medical Sciences, 1977
Sera from individuals in an outbreak of viral hepatitis in a multifamily household, probably spread by contaminated food, were studied for antibodies to hepatitis A virus (anti-HAV), and selected acute phase sera were inoculated into marmosets. Significant rises in anti-HAV titers between acute and convalescent sera occurred in all of 15 individuals in
L F, Barker, J L, Dienstag, D E, Lorenz, R H, Purcell, D C, Wong, S M, Feinstone, M R, Peterson, M W, Rosen   +7 more
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Cell culture and animal models for human viral hepatitis

Hepatology Research, 2004
Abstract Human hepatitis viruses are currently the subjects of intense investigation because of the tremendous clinical impact of these agents on human health. For other viral infections, cell culture and animal models have played crucial roles in the development of vaccines and drug therapies as well as characterization of viral life cycles. However,
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Pathogenic molecular mechanisms in an animal model of fulminant hepatic failure: Rabbit hemorrhagic viral disease

Journal of Laboratory and Clinical Medicine, 2004
In this study we sought to determine whether molecular mechanisms involved in the pathogenesis of fulminant hepatic failure are present in rabbits experimentally infected with rabbit hemorrhagic disease virus (RHDV). The activities of aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase, as well as bilirubin concentration ...
Sonia, Sánchez-Campos, Marcelino, Alvarez, Jesus M, Culebras, Javier, Gonzalez-Gallego, Maria J, Tuñón   +4 more
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Hepatitis B treatment: rational combination chemotherapy based on viral kinetic and animal model studies

Antiviral Research, 2002
Hepatitis B virus (HBV) causes a generally non-cytopathic infection in the liver. Even though HBV is a DNA virus, it replicates via reverse transcription which is coordinated within the viral nucleocapsid by the virus-specific polymerase. The major transcriptional template is the viral mimichromosome from which the viral DNA exists as a covalently ...
Lewin, S, Walters, T, Locarnini, S
openaire   +5 more sources