Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions
MedComm, Volume 7, Issue 3, March 2026.Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song +10 more
wiley +1 more source
Correlation Analysis Between HLA Polymorphisms and Immune Response to Hepatitis B Vaccine in Children with Acute Lymphoblastic Leukemia. [PDF]
Vaccines (Basel)Zhang R +6 more
europepmc +1 more source
Bacteriophage Therapy: Current Strategies and Future Perspectives
MedComm, Volume 7, Issue 3, March 2026.This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou +7 more
wiley +1 more source
The Role of Vaccination in Adult Solid Organ Transplantation: Updated Reviews with Recent Guidelines. [PDF]
MicroorganismsMour G +6 more
europepmc +1 more source
MedComm, Volume 7, Issue 3, March 2026.This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source
MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential
MedComm – Future Medicine, Volume 5, Issue 1, March 2026.The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman +7 more
wiley +1 more source
The Cinderella tree, Quillaja saponaria – A soap story
PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 439-451, March 2026.Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley +1 more source
Virus Biomimetic-Delivery Systems for the Production of Vaccines. [PDF]
Biomimetics (Basel)Barbinta-Patrascu ME, Negut I, Bita B.
europepmc +1 more source
PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 530-555, March 2026.Plants, like humans, have a microbiome that helps them grow, defend themselves against pathogens, acquire nutrients, and protect themselves against environmental stresses. The microbiome of tomatoes, a staple crop grown worldwide, could be utilized not only to reduce fertilizer and pesticide applications, but also to clean up harmful pollutants ...
Sean Lindert +3 more
wiley +1 more source
Adherence to Recommended Immunisation Schedules for Patients With Inflammatory Bowel Disease (IBD) on Biologics: A Retrospective Study at Our Lady's Hospital, Navan, Ireland. [PDF]
CureusKhan A, Shahab M, Anwar MM.
europepmc +1 more source