Results 91 to 100 of about 119,227,947 (264)

Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein [PDF]

, 2010
The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 ...
Dubuisson, J., J. Dubuisson, A. H. Patel, G. Vieyres, Patel, A.H., Vieyres, G.   +5 more
core   +1 more source

Epidemiología de las hepatitis virales en México Epidemiology of viral hepatitis in Mexico

Salud Pública de México, 2011
Las hepatitis virales son una de las causas principales de daño hepático en México. En este estudio se analiza el estado actual de las hepatitis virales en México. La Secretaría de Salud informa un total de 192 588 casos de hepatitis virales entre 2000 y
Arturo Panduro, Griselda Escobedo Melendez, Nora A Fierro, Bertha Ruiz Madrigal, Eloy Alfonso Zepeda-Carrillo, Sonia Román   +5 more
doaj  

Early predictive efficacy of core antigen on antiviral outcomes in genotype 1 hepatitis C virus infected patients

Brazilian Journal of Infectious Diseases, 2015
Response-guided therapy is of limited use in developing countries because hepatitis C virus RNA detection by sensitive molecular methods is time- and labor-consuming and expensive.
Bo Feng, Rui-Feng Yang, Hai-Ying Zhang, Bi-Fen Luo, Fan-Yun Kong, Hui-Ying Rao, Qian Jin, Xu Cong, Lai Wei   +8 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Stimulation requirement and pathogenetic significance of T cells during chronic viral hepatitis. [PDF]

, 2007
Hepatitis B virus (HBV) and Hepatitis C virus (HCV) are important causes of liver inflammation and fibrosis. More than 500 million people are persistently infected worldwide and consequently are at increased risk of developing chronic liver disease ...
Kennedy, P.
core  

Erratum to 'The management of chronic hepatitis B in the immunocompromised patient: recommendations from a single topic meeting' [J. Clin. Virol. 41 (4) 2008 243-254] [PDF]

, 2008
Patients with chronic hepatitis B virus (HBV) infection have a substantial risk of reactivation and jaundice following the use of immunosuppressant therapy.
Pol, Stanislas, Hayes, Peter C, Mills, Peter R, Carman, William, Mutimer, David, Barclay, Stephen, Benhamou, Yves, Cameron, Sheila, Pol, S, Barclay, S, Hayes, Patrick, Benhamou, Y, Carman, W, Cameron, S, Mills, P   +14 more
core   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Hepatitis C Treatment: A Community-Based, Multidisciplinary Approach to Increase Access and Improve Health Perceptions [PDF]

, 2012
Hepatitis C is a major international health care dilemma, occurring frequently in populations who suffer from other health care disparities. Hepatitis C is the most common blood-borne infection and the leading cause of liver disease in the United States (
Leigh, Elaine A.
core  

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

Advanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti, Yoshiki Yasukochi, Gianluca Angiola, Takaharu Ueno, Saki Ikegami, Rintaro Okawa, Tetsuya Adachi, Wenliang Zhu, Osam Mazda, Alfio Grillo, Koichiro Higasa, Kazu Okuma   +11 more
wiley   +1 more source