Results 21 to 30 of about 94,212 (236)

Elevation of Memory Cytotoxic T Lymphocytes, Including Human T Lymphotropic Virus Type 1 Tax-Specific and Hepatitis Virus Type C-Specific Cytotoxic T Lymphocytes, in a Patient with Adult T-Cell Leukemia/Lymphoma and Hepatocellular Carcinoma

Case Reports in Oncology, 2020
Herein, we present the case of a patient who suffered from adult T-cell leukemia/lymphoma (ATLL) and hepatocellular carcinoma (HCC) after obtaining a sustained virological response following treatment with a direct-acting antiviral (DAA) at different ...
Tatsuro Jo, Yohei Kaneko, Takayuki Oishi, Kaori Matsuzaka, Haruna Shioya, Takahiro Sakai, Hiroo Tomoinaga, Shizuka Hayashi, Masatoshi Matsuo, Jun Taguchi   +9 more
doaj   +1 more source

Hepatitis D Virus Infection of Mice Expressing Human Sodium Taurocholate Co-transporting Polypeptide.

PLoS Pathogens, 2015
Hepatitis D virus (HDV) is the smallest virus known to infect human. About 15 million people worldwide are infected by HDV among those 240 million infected by its helper hepatitis B virus (HBV).
Wenhui He, Bijie Ren, Fengfeng Mao, Zhiyi Jing, Yunfei Li, Yang Liu, Bo Peng, Huan Yan, Yonghe Qi, Yinyan Sun, Ju-Tao Guo, Jianhua Sui, Fengchao Wang, Wenhui Li   +13 more
doaj   +1 more source

Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells. [PDF]

PLoS Pathogens, 2013
Persistent infections with hepatitis C virus (HCV) may result in life-threatening liver disease, including cirrhosis and cancer, and impose an important burden on human health.
Hiromichi Dansako, Daisuke Yamane, Christoph Welsch, David R McGivern, Fengyu Hu, Nobuyuki Kato, Stanley M Lemon   +6 more
doaj   +1 more source

Recent Advances in Hepatitis C Virus Cell Entry

Viruses, 2010
More than 170 million patients worldwide are chronically infected with hepatitis C virus (HCV). Prevalence rates range from 0.5% in Northern European countries to 28% in some areas of Egypt.
Jean Dubuisson, Birke Bartosch
doaj   +1 more source

A super TLR agonist to improve efficacy of dendritic cell vaccine in induction of anti-HCV immunity. [PDF]

PLoS ONE, 2012
Persistent infections caused by pathogens such as hepatitis C virus are major human diseases with limited or suboptimal prophylactic and therapeutic options.
Bangxing Hong, Sung-Hyung Lee, Xiao-Tong Song, Lindsey Jones, Keigo Machida, Xue F Huang, Si-Yi Chen   +6 more
doaj   +1 more source

Tin oxide nanowires suppress herpes simplex virus-1 entry and cell-to-cell membrane fusion.

PLoS ONE, 2012
The advent of nanotechnology has ushered in the use of modified nanoparticles as potential antiviral agents against diseases such as herpes simplex virus 1 and 2 (HSV-1) (HSV-2), human immunodeficiency virus (HIV), monkeypox virus, and hepatitis B virus.
James Trigilio, Thessicar E Antoine, Ingo Paulowicz, Yogendra K Mishra, Rainer Adelung, Deepak Shukla   +5 more
doaj   +1 more source

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex

Cells, 2020
The hepatitis B virus (HBV) regulatory HBx protein is required for infection, and its binding to cellular damaged DNA binding protein 1 (DDB1) is critical for this function.
Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle   +7 more
doaj   +1 more source

TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients

OncoImmunology, 2021
Accumulating evidence indicates that immune checkpoint inhibitors (ICIs) can restore CD8+ cytotoxic T lymphocyte (CTL) functions in preclinical models of acute myeloid leukemia (AML).
Jana Rakova, Iva Truxova, Peter Holicek, Cyril Salek, Michal Hensler, Lenka Kasikova, Josef Pasulka, Monika Holubova, Marek Kovar, Daniel Lysak, Justin P. Kline, Zdenek Racil, Lorenzo Galluzzi, Radek Spisek, Jitka Fucikova   +14 more
doaj   +1 more source

Polymorphisms of the Hepatitis A Virus Cellular Receptor 1 in African Green Monkey Kidney Cells Result in Antigenic Variants That Do Not React with Protective Monoclonal Antibody 190/4 [PDF]

Journal of Virology, 1998
ABSTRACT Monoclonal antibody (MAb) 190/4 blocks binding of hepatitis A virus (HAV) to the HAV cellular receptor 1 (havcr-1) and protects African green monkey kidney (AGMK) clone GL37 cells (GL37 cells) against HAV infection. BS-C-1 and CV-1 cells, two widely used AGMK cell lines, did not react with MAb 190/4 but expressed havcr-1, as judged ...
D, Feigelstock, P, Thompson, P, Mattoo, G G, Kaplan   +3 more
openaire   +2 more sources

Effect of combined siRNA of HCV E2 gene and HCV receptors against HCV

Virology Journal, 2011
Background/Aim Hepatitis C virus (HCV) is a major threat as almost 3% of the world's population (350 million individual) and 10% of the Pakistani population is chronically infected with this virus. RNA interference (RNAi), a sequence-specific degradation
Ashfaq Usman Alli A, Ahmad Waqar, Khan Mahwish, Ijaz Bushra, Samreen Baila, Khaliq Saba, Jahan Shah, Hassan Sajida   +7 more
doaj   +1 more source