Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies
, 2009 The use of neutralizing antibodies is one of the most successful methods to interfere with receptor–ligand interactions in vivo. In particular blockade of soluble inflammatory mediators or their corresponding cellular receptors was proven an effective ...
Christen, Urs +2 more
core +1 more source
The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]
, 2014 Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, N J +5 more
core +1 more source
Frontiers in Molecular BiosciencesBackgroundMitochondria have always been considered too be closely related to the occurrence and development of malignant tumors. However, the bioinformatic analysis of mitochondria in lung adenocarcinoma (LUAD) has not been reported yet.MethodsIn the ...
Xianqiao Wu +7 more
doaj +1 more source
Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers. [PDF]
, 2014 We have previously documented the inhibitory activity of RNA aptamers to the RNA-dependent RNA polymerase of foot-and-mouth disease virus (3D(pol)). Here we report their modification and use with a subgenomic replicon incorporating GFP (pGFP-PAC replicon)
Forrest, S +11 more
core +1 more source
Cellular tropism and cell-to-cell fusion properties of the infectious bronchitis virus spike glycoprotein [PDF]
There are numerous vaccines available for the control of infectious bronchitis virus (IBV) in poultry, however protection is short-lived and poorly cross-protective between strains.
Bickerton, Erica Jane
core
Identification and expression of a murine cytomegalovirus early gene coding for an Fc receptor [PDF]
, 1994 Several herpesviruses, including cytomegalovirus, induce receptors for the Fc domain of murine immunoglobulin G (IgG) molecules. Viral genes coding for these receptors have been characterized only for alphaherpesviruses. In this report, we describe a new
Ulrich +10 more
core
PD-1 receptor (PDCD1; PD-1; CD279); programmed cell death 1 ligand 1 (CD274 molecule; PD-L1; B7-H1); hepatitis A virus cellular receptor 2 (HAVCR2; TIM3) [PDF]
Science-Business eXchange, 2010 openaire +3 more sources
Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies
, 2013 PMCID: PMC3581439This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Ovecka, M +47 more
core +1 more source
Mechanism(s) of hepatitis C virus induced liver injury [PDF]
, 2012 Hepatitis C virus (HCV) infects hepatocytes of the liver causing progressive liver disease including; fibrosis, cirrhosis and hepatocellular carcinoma.
Wilson, Garrick Kenardo
core