Results 51 to 60 of about 478,399 (303)

Monitoring response to hepatitis B and C in EU/EEA: testing policies, availability of data on care cascade and chronic viral hepatitis-related mortality – results from two surveys (2016) [PDF]

, 2018
Objectives: The World Health Organization (WHO) developed a European Regional Action Plan (EAP) to fast-track action towards the goal of eliminating viral hepatitis. Robust monitoring is essential to assess national programme performance.
De Brujin, European Centre for Disease Prevention and Control, European Centre for Disease Prevention and Control, European Centre for Disease Prevention and Control, European Centre for Disease Prevention and Control, European Centre for Disease Prevention and Control, European Centre for Disease Prevention and Control, European Centre for Disease Prevention and Control, Iyengar, World Health Organisation, World Health Organisation, World Health Organisation   +11 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Schistosomiasis japonicum diagnosed on liver biopsy in a patient with hepatitis B co-infection: a case report [PDF]

, 2014
Introduction Chronic hepatitis B virus and schistosomiasis are independently associated with significant mortality and morbidity worldwide. Despite much geographic overlap between these conditions and no reason why co-infection should not exist, we ...
Andrews, Tim, Beadsworth, Mike BJ, Michie, Kirsten, Miller, Alastair RO, Nsutebu, Emmanuel F, Parris, Victoria, Squire, Bertie   +6 more
core   +3 more sources

Chronic hepatitis B: Update 2009 # [PDF]

Hepatology, 2009
No abstract.
Lok, Anna Suk-Fong, McMahon, Brian J.
openaire   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Killer cell immunoglobulin-like receptor alleles influence susceptibility to occult hepatitis B infection in West African population

Journal of Public Health in Africa, 2023
Occult hepatitis B infection (OBI) is a public health problem in Burkina Faso. OBI represents a risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC).
Momeiyi M. Bazie, Florencia W. Djigma, Mahamoudou Sanou, Pegdwendé A. Sorgho, Abdoul K. Ouattara, Dorcas Obiri-Yeboah, Nadege Kapieko, Herman K. Sombie, Prosper Bado, Edwige T. Yelemkoure, Isabelle T. Kiendrebeogo, Marius B. Nagalo, Albert T. Yonli, Jacques Simpore   +13 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Optimized RNA interference therapeutics combined with interleukin-2 mRNA for treating hepatitis B virus infection

Signal Transduction and Targeted Therapy
This study aimed to develop a pan-genotypic and multifunctional small interfering RNA (siRNA) against hepatitis B virus (HBV) with an efficient delivery system for treating chronic hepatitis B (CHB), and explore combined RNA interference (RNAi) and ...
Wenjing Zai, Min Yang, Kuan Jiang, Juan Guan, Huijing Wang, Kongying Hu, Chao Huang, Jieliang Chen, Wei Fu, Changyou Zhan, Zhenghong Yuan   +10 more
doaj   +1 more source

Evolution of hepatitis B virus liver disease after hepatic replacement. Practical and theoretical considerations [PDF]

, 1990
The morphologic evolution of hepatitis B virus (HBV) liver disease in 45 hepatic allograft recipients who were HBV surface-antigen positive (HBs-Ag+) at the time of liver replacement and who survived for more than 60 days was studied by routine ...
Demetris, AJ, Fung, JJ, Iwaki, Y, Ming, W, Starzl, TE, Sysyn, G, Todo, S, Trager, J, Van Thiel, DH   +8 more
core   +1 more source

Future prevention and treatment of chronic hepatitis B infection [PDF]

, 2012
Vaccination for hepatitis B virus (HBV) infection and treatment for chronic hepatitis B, while effective for primary prevention and control of the disease, still have their limitations. Global coverage of HBV immunization needs improvement.
Fung, J, Lai, CL, Seto, WK, Yuen, MF
core   +1 more source