Results 41 to 50 of about 912,795 (359)
Virus ResearchThe detection of hepatitis B surface antigen (HBsAg) is fundamental for the diagnosis of chronic hepatitis B (CHB). However, current diagnostic assays that rely on antibodies targeting the conformational “a” determinant of HBsAg are frequently ...
Yansong Chen +8 more
doaj +1 more source
Level of physicians’ awareness of epidemiology, outcomes, prevention and treatment of chronic hepatitis B and C [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2018 Objective. To evaluate a level of physicians’ awareness of the specific issues of epidemiology, outcomes, prevention and treatment of chronic hepatitis B and C. Materials and Methods.
Baramzina S.V.
doaj +1 more source
HBV - infection in children with perinatal infection. Clinical report of familial hepatitis B
Журнал инфектологии, 2021 Hepatitis B, despite of being a controlled infection today, is one of the most common form of hepatitis in the world. According to the experts' evaluation there are about 3 million patients with chronic hepatitis B in our country.
I. V. Shilova +3 more
doaj +1 more source
Журнал инфектологии, 2014 Purpose: to evaluate the effect of additional vaccination of adult HBV- infection years 2007–2010 on the incidence of chronic hepatitis B and its outcomes on the example of the Kirov region.Materials and Methods: the evaluation of epidemiological ...
S. V. Baramzina, A. L. Bondarenko
doaj +1 more source
EASL clinical practice guidelines: Management of chronic hepatitis B virus infection.
Journal of Hepatology, 2012 Our understanding of the natural history of hepatitis B virus (HBV) infection and the potential for therapy of the resultant disease is continuously improving.
semanticscholar +1 more source
Hepatitis B virus infection in the Republic of Yemen [PDF]
A community-based cross-sectional household seroepdemiological survey was conducted in the Republic of Yemen to estimate the prevalence of HBV infection as well as hepatitis B vaccine coverage and effectiveness amongst children vaccinated in the ...
Qirbi, Naseeb
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection [PDF]
, 2010 NK cells are enriched in the liver, constituting around a third of intrahepatic lymphocytes. We have previously demonstrated that they upregulate the death ligand TRAIL in patients with chronic hepatitis B virus infection (CHB), allowing them to kill ...
Richard J. Gilson +50 more
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source